Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Heloise Brice"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 6, Iss 1, p 22 (2010)
The silyl enol ether derivatives of ketones or esters tethered by a hydrocarbon or ether linkage to the 3-position of a pyridine ring undergo dearomatising nucleophilic attack on the ring once it is activated (as an acylpyridinium species) by the add
Externí odkaz:
https://doaj.org/article/385fef0e7809495e9cc015e11ea7f238
Publikováno v:
Organic Letters. 10:3089-3092
Treatment of N-arylisonicotinamides with trifluoromethanesulfonic anhydride triggers intramolecular nucleophilic attack of the aryl ring on the 4-position of the pyridinium intermediate. The products are spirocyclic dihydropyridines which can be conv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b20be73c05a83dcde29013ef00dfa0
https://doi.org/10.1021/ol801092s
https://doi.org/10.1021/ol801092s
Publikováno v:
ChemInform. 44
N-alkenyl pyridinecarboxamides undergo dearomatizing spirocyclization initiated by pyridine acylation and followed by intramolecular trapping of the resulting pyridinium cation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fbb73ecebb6d94527f2d8f554e4f502
https://doi.org/10.1002/chin.201335091
https://doi.org/10.1002/chin.201335091
Publikováno v:
Organic letters. 15(8)
On treatment with acylating or sulfonylating agents, N-alkenyl pyridine carboxamides (N-pyridinecarbonyl enamines) undergo a dearomatizing cyclization initiated by pyridine acylation and followed by intramolecular trapping of the resulting pyridinium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e4b93980793676067b0ee3e2ae25ca
https://pubmed.ncbi.nlm.nih.gov/23547947
https://pubmed.ncbi.nlm.nih.gov/23547947
Autor:
Per H. Svensson, Laura Goldie, William J. Kerr, Philip S. Keegan, Duncan M. Gill, Heloise Brice
Publikováno v:
ChemInform. 43
A range of C-substituted oxabispidines are synthesized from commercially available chiral epoxypropylphthalimide (I) using a novel stereoselective intramolecular Mannich reaction [(XI)] as key transformation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8db70f5b26eb5e4e870aaa33be695b2e
https://doi.org/10.1002/chin.201237173
https://doi.org/10.1002/chin.201237173
Autor:
Per H. Svensson, Laura Goldie, Heloise Brice, William J. Kerr, Philip S. Keegan, Duncan M. Gill
A range of chiral, optically-enriched bicyclic oxabispidines were prepared from (S)-(-)-2,3-epoxypropylphthalimide using an efficient sequence featuring a stereocontrolled intramolecular Mannich reaction as the key transformation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a659d25d3e18a125b21cb4cbbca7456
https://eprints.hud.ac.uk/id/eprint/13599/1/Oxabispidine_CC_2012_published.pdf
https://eprints.hud.ac.uk/id/eprint/13599/1/Oxabispidine_CC_2012_published.pdf
Autor:
Jonathan Clayden, Heloise Brice
Publikováno v:
ChemInform. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d1521cfd534c1931487f9d9fce86cd7
https://doi.org/10.1002/chin.200935142
https://doi.org/10.1002/chin.200935142
Publikováno v:
ChemInform. 39
Treatment of N-arylisonicotinamides with trifluoromethanesulfonic anhydride triggers intramolecular nucleophilic attack of the aryl ring on the 4-position of the pyridinium intermediate. The products are spirocyclic dihydropyridines which can be conv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85021f1e0cc8357863271db189bc5b77
https://doi.org/10.1002/chin.200848138
https://doi.org/10.1002/chin.200848138
Autor:
Heloise Brice, Jonathan Clayden
Publikováno v:
Chemical Communications. :1964
Isonicotinamides carrying N-furanylmethyl, N-pyrrolylalkyl or N-thiophenylmethyl substituents at nitrogen undergo cyclisation induced by an electrophile, giving spirocyclic compounds or doubly spirocyclic compounds in which both the nucleophilic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff332adb25bf20bd97866b97ef8df46
https://doi.org/10.1039/b901558b
https://doi.org/10.1039/b901558b