Proteomic analysis of gastrocnemius muscle in rats with streptozotocin-induced diabetes and chronically exposed to fluoride.

Autor: Aline Lima Leite, Janete Gualiume Vaz Madureira Lobo, Heloísa Aparecida Barbosa da Silva Pereira, Mileni Silva Fernandes, Tatiani Martini, Fernanda Zucki, Dóris Hissako Sumida, Alfredo Rigalli, Marília Afonso Rabelo Buzalaf

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e106646 (2014)

Administration of high doses of fluoride (F) can alter glucose homeostasis and lead to insulin resistance (IR). This study determined the profile of protein expression in the gastrocnemius muscle of rats with streptozotocin-induced diabetes that were

Externí odkaz: https://doaj.org/article/e63c003e0f774fa493f58fe3142658d3

Proteomic analysis of liver in rats chronically exposed to fluoride.

Autor: Heloísa Aparecida Barbosa da Silva Pereira, Aline de Lima Leite, Senda Charone, Janete Gualiume Vaz Madureira Lobo, Tania Mary Cestari, Camila Peres-Buzalaf, Marília Afonso Rabelo Buzalaf

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e75343 (2013)

Fluoride (F) is a potent anti-cariogenic element, but when ingestion is excessive, systemic toxicity may be observed. This can occur as acute or chronic responses, depending on both the amount of F and the time of exposure. The present study identifi

Externí odkaz: https://doaj.org/article/a9cbe40b8ec647549610147b56cc96a0

Increase of complex I and reduction of complex II mitochondrial activity are possible adaptive effects provoked by fluoride exposure

Autor: Heloísa Aparecida Barbosa da Silva Pereira, Fabrício Soares Pereira, Juliana Sanches Trevizol, Valdecir Faria Ximenes, Aline Dionizio, Flávia Godoy Iano, Marília Afonso Rabelo Buzalaf, Tamara Teodoro Araujo

Publikováno v: Heliyon, Vol 7, Iss 1, Pp e06028-(2021)
Heliyon
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Fluoride (F) can induce changes in the expression of several liver proteins, most of them localized in the mitochondria and its effect is dose- and time-dependent. This study analyzed the effect of distinct F concentrations and exposure periods on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d4e05b397c556f091519c4e648030e
http://www.sciencedirect.com/science/article/pii/S240584402100133X

Effect of Duration of Exposure to Fluoride and Type of Diet on Lipid Parameters and De Novo Lipogenesis

Autor: Isabela Tomazini Sabino-Arias, Mileni da Silva Fernandes, Fabielle Sales Raymundo, Marília Afonso Rabelo Buzalaf, Fernando Neves Nogueira, Tânia Mary Cestari, Aline Dionizio, Tamara Teodoro Araujo, Rui A. Carvalho, Karina Aparecida de Oliveira, Heloísa Aparecida Barbosa da Silva Pereira

Publikováno v: Biological Trace Element Research. 190:157-171

The effect of duration of chronic treatment with fluoride (F, 50 mg/L as NaF) on the lipid profile, lipid droplets and triglycerides (TG) in liver was evaluated in mice with nonalcoholic fatty liver disease (NAFLD) previously induced by hyperlipidic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fada9c09d4601f914ecfadb6b0522354
https://doi.org/10.1007/s12011-018-1542-4

Changes in energy metabolism induced by fluoride: Insights from inside the mitochondria

Autor: Heloísa Aparecida Barbosa da Silva Pereira, Mileni da Silva Fernandes, Tamara Teodoro Araujo, Thamyris de Souza Carvalho, Camila do Carmo Sanchez, Aline Dionizio, Marília Afonso Rabelo Buzalaf

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

The mechanisms involved in changes in energy metabolism caused by excessive exposure to fluoride (F) are not completely understood. The present study employed proteomic tools to investigate the molecular mechanisms underlying the dose- and time-depen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c813dc98ae5f6b7d488fae0ebf227cf
https://pubmed.ncbi.nlm.nih.gov/31325826