Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Helmy I. Heiba"'
Publikováno v:
Research on Chemical Intermediates. 43:4657-4681
A series of new pyridone 5, 6, 8a–j, hydrazone 7a–j, and thiophene 9–12 derivatives bearing a sulfonamide moiety were synthesized from the starting material 4-chloro-N-(4-(1-(2-(2-cyanoacetyl)hydrazono)ethyl)phenyl) benzenesulfonamide 4. The ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9927df145120a16f79061bf4aead5486
https://doi.org/10.1007/s11164-017-2903-x
https://doi.org/10.1007/s11164-017-2903-x
Publikováno v:
European Journal of Medicinal Chemistry. 117:8-18
A novel series of sulfonamide derivatives 4-21 have been synthesized starting from the strategic starting material (E)-4-Chloro-N-(4-(1-(2-(2-cyanoacetyl)hydrazono)ethyl)phenyl) benzenesulfonamide 4. Two series of hydrazone 5-9, and pyridone 10-21 de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404b8023dd1b27a5ce1c7f06c3864f89
https://doi.org/10.1016/j.ejmech.2016.04.009
https://doi.org/10.1016/j.ejmech.2016.04.009
Publikováno v:
Bioorganic chemistry. 80
Two series of 2-aminopyridine derivatives 6-17 and tyrphostin AG17 analogs 18-22 bearing 4-methylbenzenesulfonamide moiety were designed and synthesized as anticancer compounds. The synthesized compounds were biologically evaluated for their cytotoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f4233ee04295c3b8e3fb593e096a3e
https://pubmed.ncbi.nlm.nih.gov/29966874
https://pubmed.ncbi.nlm.nih.gov/29966874
Publikováno v:
Research on Chemical Intermediates. 41:647-661
Because of the reported anticancer activity of quinolines and pyrimidoquinolines containing the biologically active sulfonamide moiety, a new series of quinoline and pyrimidoquinoline derivatives were synthesized and tested for in-vitro anticancer ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ab60b793679682231e6f25b1d962e45
https://doi.org/10.1007/s11164-013-1218-9
https://doi.org/10.1007/s11164-013-1218-9
Publikováno v:
European Journal of Medicinal Chemistry. 53:403-407
The present work reports the synthesis of some new Schiff bases, 5-(substituted benzylideneamino)-6-cyano-7H-7-(4-methoxyphenyl)-2-(4-sulphamoylphenylamino) pyrano[2,3-d]thiazole (5-15). The design of the structures of these compounds complies with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1fb11fddddcad33549288896014512
https://doi.org/10.1016/j.ejmech.2012.04.009
https://doi.org/10.1016/j.ejmech.2012.04.009
Publikováno v:
Arzneimittelforschung. 56:593-599
The syntheses of novel 1,2,4-triazolothi-enopyrimidine derivatives (4a,b), thiourea derivatives (5-8) and biscompounds having a thieno[2,3-d]pyrimidine nucleus (13-16) utilizing the 2-isothiocyanato derivatives 2a,b are reported. The structures of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959a733fb4c7081441657acb0d56bf28
https://doi.org/10.1055/s-0031-1296757
https://doi.org/10.1055/s-0031-1296757
Publikováno v:
Arzneimittelforschung. 58:35-41
The present work reports the possible utility of 4-(5,5-dimethyl-3-oxo-cyclohex-1-enylamino)benzenesulfonamide in the synthesis of some novel 4-(quinolin-1-yl) benzenesulfonamide derivatives (6a-o). Structures of the newly synthesized compounds were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b16cbf91fbc204d835f0ca25bbda3af
https://doi.org/10.1055/s-0031-1296464
https://doi.org/10.1055/s-0031-1296464
Publikováno v:
Arzneimittelforschung. 60:48-55
Several novel pyrazole (11-18) and pyrimidine (19-23) derivatives were synthesized starting from different sulfonamides and different active methylenes. The synthesized compounds were characterized by elemental analysis, IR, 1H-NMR and mass spectral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086efb7fd50902d6264ac240f662f3a3
https://doi.org/10.1055/s-0031-1296248
https://doi.org/10.1055/s-0031-1296248
Autor:
Mostafa M. Ghorab, Mostafa G.M. El-Gazzar, Helmy I. Heiba, Fatma A. Ragab, Marwa G. El-Gazzar
Publikováno v:
Acta Pharmaceutica. 61:415-425
Synthesis, in vitro anticancer screening and radiosensitizing evaluation of some new 4-[3-(substituted)thioureido]-N-(quinoxalin-2-yl)-benzenesulfonamide derivatives Sulfonamides and quinoxaline derivatives possess many types of biological activities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1abdbcf2b916ddb6d0cbaf7bad1b64a
https://doi.org/10.2478/v10007-011-0040-4
https://doi.org/10.2478/v10007-011-0040-4
Publikováno v:
European Journal of Medicinal Chemistry. 46:5120-5126
Recently, it has been reported that compounds bearing a sulfonamide moiety posses many types of biological activities, including anticancer activity. There are a variety of mechanisms for their anticancer activity, and the most prominent mechanism is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea1e9f12a8747867c9d93e95bd2a072
https://doi.org/10.1016/j.ejmech.2011.08.026
https://doi.org/10.1016/j.ejmech.2011.08.026