Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Helmut Wieczorek"'
Autor:
Chun Feng Song, Kostas Papachristos, Shaun Rawson, Markus Huss, Helmut Wieczorek, Emanuele Paci, John Trinick, Michael A Harrison, Stephen P Muench
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82207 (2013)
The V-ATPase is a membrane-bound protein complex which pumps protons across the membrane to generate a large proton motive force through the coupling of an ATP-driven 3-stroke rotary motor (V1) to a multistroke proton pump (Vo). This is done with nea
Externí odkaz:
https://doaj.org/article/4968aed92d3641f78b93674272169417
Autor:
Helmut Wieczorek, Felix Tiburcy, Anna-Christina Schulz-Fincke, Meryem Köse, Johal Ruiz, Stephan Scheeff, Christa E. Müller, Dirk Menche, Michael Gütschow, Solenne Rivière, Aliaa Abdelrahman
Publikováno v:
Journal of medicinal chemistry. 63(4)
Vacuolar type ATPase (V-ATPase) has recently emerged as a promising novel anticancer target based on extensive in vitro and in vivo studies with archazolids, complex polyketide macrolides, which present the most potent V-ATPase inhibitors known to da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5a6118fbe71b40ede0344def29dfc7
https://pubmed.ncbi.nlm.nih.gov/31990540
https://pubmed.ncbi.nlm.nih.gov/31990540
Publikováno v:
Biochemical Journal. 475:3239-3254
The solute carrier 45 family (SLC45) was defined in the course of the Human Genome Project and consists of four members, A1–A4, which show only 20–30% identity of amino acid sequences among each other. All these members exhibit an identity of ∼
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb3fc50d0ce765dbdaff85dd21685658
https://doi.org/10.1042/bcj20180293
https://doi.org/10.1042/bcj20180293
Autor:
Helmut Wieczorek, Olga Vitavska
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 469:1433-1442
In the present study, we describe the detection and analysis of a novel type of sugar transporter in mammalian spermatozoa. This transporter belongs to the SLC45 family for which two features are remarkable and distinguish it from other known familie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f15346c581650bc233987f799a74fe7b
https://doi.org/10.1007/s00424-017-2024-9
https://doi.org/10.1007/s00424-017-2024-9
Publikováno v:
The Biochemical journal. 475(20)
The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6de7ac10a7ee50e15b4fac929325fe84
https://pubmed.ncbi.nlm.nih.gov/30237153
https://pubmed.ncbi.nlm.nih.gov/30237153
Autor:
Olga, Vitavska, Helmut, Wieczorek
Publikováno v:
Pflugers Archiv
In the present study, we describe the detection and analysis of a novel type of sugar transporter in mammalian spermatozoa. This transporter belongs to the SLC45 family for which two features are remarkable and distinguish it from other known familie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de61b4f9d58614833a19e09fc467efdf
https://pubmed.ncbi.nlm.nih.gov/28689241
https://pubmed.ncbi.nlm.nih.gov/28689241
Autor:
John Trinick, Helmut Wieczorek, Clair Phillips, Stephen P. Muench, Markus Huss, Sjors H.W. Scheres, Olga Vitavska, Michael A. Harrison
Publikováno v:
Journal of Molecular Biology
The vacuolar H+-ATPase (V-ATPase) is an ATP-driven proton pump essential to the function of eukaryotic cells. Its cytoplasmic V1 domain is an ATPase, normally coupled to membrane-bound proton pump Vo via a rotary mechanism. How these asymmetric motor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c6d9436b54dcb14627d1cf5f99a961
http://europepmc.org/articles/PMC3899036
http://europepmc.org/articles/PMC3899036
Publikováno v:
Journal of Cell Science. 124:1984-1991
According to a classic tenet, sugar transport across animal membranes is restricted to monosaccharides. Here, we present the first report of an animal sucrose transporter, SCRT, which we detected in Drosophila melanogaster at each developmental stage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea511bb5c91bbb5d5ca34c91ef23a1d
https://doi.org/10.1242/jcs.082024
https://doi.org/10.1242/jcs.082024
Autor:
Helmut Wieczorek, Florenz Sasse, Markus Huss, Sebastian Essig, Svenja Bockelmann, Dirk Menche, Nicole Horstmann
Publikováno v:
Journal of Natural Products. 74:1100-1105
Two structurally novel analogues of the macrolides archazolids A and B, archazolid A-15-O-β-D-glucopyranoside (archazolid E, 5) and iso-archazolid B (archazolid F, 6), were isolated from the myxobacterium Cystobacter violaceus and Archangium gephyra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f147b7e022ec9ca4c26338f8eaf222
https://doi.org/10.1021/np200036v
https://doi.org/10.1021/np200036v
Autor:
Paultheo von Zezschwitz, Nadja Burkard, Christin Nardmann, Stephanie Grond, Helmut Wieczorek, Tobias Bender, Johannes Westmeier, Markus Huss
Publikováno v:
European Journal of Organic Chemistry. 2010:2176-2181
(Trifluoromethyl)diazirines are well established photoaffinity labels (PAL) used in biochemical investigations to create covalent ligand-receptor bonds. Two new diazirinylbenzoic acids 8b,c with perfluorobutyl and perfluorooctyl chains (F-PAL) were e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70dd48b5f271e74a3825f2072a91ce5a
https://doi.org/10.1002/ejoc.200901463
https://doi.org/10.1002/ejoc.200901463