Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Helmut Ponta"'
The small G-protein Ras is a tightly controlled regulator of cell fate. Prolonged or persistent arrest in the activated GTP-loaded state by mutation of Ras as in lung cancer or in a Ras–GTPase-activating protein as in neurofibromatosis type 1 promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39af74417b82d7b4287f880049bebb78
https://doi.org/10.1158/0008-5472.c.6495354.v1
https://doi.org/10.1158/0008-5472.c.6495354.v1
Supplementary Figure 3 from Merlin/Neurofibromatosis Type 2 Suppresses Growth by Inhibiting the Activation of Ras and Rac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f4f73d22c76074bd465a5e3d24f411
https://doi.org/10.1158/0008-5472.22366935.v1
https://doi.org/10.1158/0008-5472.22366935.v1
Supplementary Figure 1 from Merlin/Neurofibromatosis Type 2 Suppresses Growth by Inhibiting the Activation of Ras and Rac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8129a09bd68225064e64acbb47cce13
https://doi.org/10.1158/0008-5472.22366941
https://doi.org/10.1158/0008-5472.22366941
Supplementary Figure 2 from Merlin/Neurofibromatosis Type 2 Suppresses Growth by Inhibiting the Activation of Ras and Rac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd6fb4fadaccb352090fe6eceab18ec
https://doi.org/10.1158/0008-5472.22366938.v1
https://doi.org/10.1158/0008-5472.22366938.v1
Supplementary Figure 1 Legend from Merlin/Neurofibromatosis Type 2 Suppresses Growth by Inhibiting the Activation of Ras and Rac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d3099422bc6b6b0c4b95c8a07f7a0aa
https://doi.org/10.1158/0008-5472.22366944
https://doi.org/10.1158/0008-5472.22366944
Autor:
Thomas Lindner, Amir Abdollahi, Katharina Jannasch, Véronique Orian-Rousseau, Jörg Kleeff, Alexandra Matzke-Ogi, Christian Schwager, Beatrix Fuchs, Marine Shatirishvili, Walter Mier, Owen J. Sansom, Jennifer P. Morton, Sara Chiblak, Arne Warth, Frauke Alves, Helmut Ponta, Bouchra Tawk
Background & Aims\ud \ud Cancer cells with high metastatic potential and stem cell–like characteristics express the cell surface marker CD44. CD44 isoforms that include the v6 exon are co-receptors for the receptor tyrosine kinases MET and Vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61509b06129a130a2f5f9f0c80311000
https://eprints.gla.ac.uk/116680/7/116680.pdf
https://eprints.gla.ac.uk/116680/7/116680.pdf
Autor:
Gerhard Christofori, Véronique Orian-Rousseau, Helmut Ponta, Alexandra Matzke, Vivienne Olaku, Imke Albrecht, Anna M. Laib, Mélanie Héroult, Kurt Ballmer-Hofer, Hellmut G. Augustin, Martina Tremmel
Publikováno v:
Blood. 114:5236-5244
A specific splice variant of the CD44 cell- surface protein family, CD44v6, has been shown to act as a coreceptor for the receptor tyrosine kinase c-Met on epithelial cells. Here we show that also on endothelial cells (ECs), the activity of c-Met is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::040fe63622e126617ae2c0acda8951a3
https://doi.org/10.1182/blood-2009-04-219204
https://doi.org/10.1182/blood-2009-04-219204
Publikováno v:
Cancer Research. 67:520-527
The small G-protein Ras is a tightly controlled regulator of cell fate. Prolonged or persistent arrest in the activated GTP-loaded state by mutation of Ras as in lung cancer or in a Ras–GTPase-activating protein as in neurofibromatosis type 1 promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ddd2caf5d5bac988d92dab35910384
https://doi.org/10.1158/0008-5472.can-06-1608
https://doi.org/10.1158/0008-5472.can-06-1608
Autor:
Helmut Ponta, Thor Kastilan, Giuseppina Pace, Véronique Orian-Rousseau, Alexandra Matzke, Peter Herrlich, Helen Morrison
Publikováno v:
Molecular Biology of the Cell. 18:76-83
In several types of cells, the activation of the receptor tyrosine kinase c-Met by its ligand hepatocyte growth factor (HGF) requires the coreceptor CD44v6. The CD44 extracellular domain is necessary for c-Met autophosphorylation, whereas the intrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6e9f44711dd3af1bd8e1051afeb6d1
https://doi.org/10.1091/mbc.e06-08-0674
https://doi.org/10.1091/mbc.e06-08-0674
Autor:
Susanne Weg-Remers, Harald König, Véronique Orian-Rousseau, Jonathan P. Sleeman, Peter Herrlich, Helen Morrison, Helmut Ponta
Publikováno v:
Europe PubMed Central
High-molecular-weight splice variants of the CD44 transmembrane protein family have been implicated in tumorigenesis and metastasis formation. By contrast, in certain tumors--for example, Burkitt's lymphoma, neuroblastomas, and prostate cancer--loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b171d060377e37541ed59f9752cc4e
https://doi.org/10.1111/j.1749-6632.2000.tb06704.x
https://doi.org/10.1111/j.1749-6632.2000.tb06704.x