Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Helmut Näher"'
Publikováno v:
JDDG: Journal der Deutschen Dermatologischen Gesellschaft. 8:332-340
Autor:
Christoffer Gebhardt, Helmut Näher
Publikováno v:
Onkopipeline. 2:101-113
Das maligne Melanom ist der wichtigste und zugleich bosartigste Tumor in der Dermatologie. Der Primartumor wird mittels Exzisionsbiopsie entfernt, wobei evidenzgesicherte Sicherheitsabstande einzuhalten sind. Da in prospektiven Studien keine Verbesse
Publikováno v:
Mycoses. 37:79-84
There is significant clinical interest in primers which are specific for fungi and do not hybridize to DNA of other eukaryotes or prokaryotes. Such primers would allow specific amplification of fungal DNA from human tissue samples containing fungi. F
Autor:
Silke S. Schwager, Ulrike Leiter, Helmut Näher, Eva B. Bröcker, Petra G. Buettner, Wolfgang Ch. Marsch, Christiane Voit, Ralf Gutzmer, Claus Garbe, Harald Gollnick
Publikováno v:
Melanoma Research. 18:112-119
This study analysed the changes of excision margins in correlation with tumour thickness as recorded over the last three decades in Germany. The study also evaluated surgical management in different geographical regions and treatment options for meta
Publikováno v:
Archives of Dermatological Research. 296:345-352
Stimulated by earlier reports on the presence of retroviruses in mouse and hamster melanoma cell lines, we addressed the question as to whether human melanoma cell lines might also harbour a retrovirus. The melanoma cell lines SK-MEL-25, SK-MEL-28, M
Autor:
Martin Deichmann, Sergij Goerdt, Claudia Jäger, Hjalmar Kurzen, Alexei Gratchev, Wolfgang Hartschuh, Hans Berger, Helmut Näher
Publikováno v:
Journal of Investigative Dermatology. 123:937-949
We present molecular and protein profiling of all acetylcholine receptors (ACh-R) in human scalp skin using PCR, in situ hybridization and double-labeling immunofluorescence. Within the epidermis, the nicotinic (n)ACh-R subunits, alpha3, alpha5, beta
Publikováno v:
Oncology. 66:411-419
Downstream of Ras, the serine/threonine kinase B-raf has recently been reported to be mutated, among other carcinomas, in a majority of melanoma cell lines with a preponderance of mutations within the kinase domain including the activating V599E tran
Autor:
Helmut Näher, Ferdinand Toberer
Publikováno v:
Journal of the American Academy of Dermatology. 67:e269-e271
Publikováno v:
Anti-Cancer Drugs. 14:515-522
It is well established that certain chemotherapeutic agents have potent antiangiogenic properties which may be part of their antitumor activity. Temozolomide (TMZ) is a lipophilic methylating agent used in the therapy of malignant melanoma and other
Autor:
Hjalmar Kurzen, Helmut Näher
Publikováno v:
coloproctology. 24:75-83
Die Inzidenz des malignen Melanoms hat sich in den letzten 20 Jahren verdreifacht. Mehr als 90% aller malignen Melanome werden heute im Stadium des Primartumors diagnostiziert. Ein wesentlicher Zugewinn in der Diagnostik ist die Einfuhrung der Sentin