Proton- and ammonium- sensing by histaminergic neurons controlling wakefulness.

Autor: Yvgenij eYanovsky, Jeffrey M Zigman, Anna L. Kernder, Alisa eBein, Ichiro eSakata, Sherri eOsborne-lawrence, Helmut L. Haas, Olga A. eSergeeva

Publikováno v: Frontiers in Systems Neuroscience, Vol 6 (2012)

Orexinergic and histaminergic neurons in the posterior hypothalamus are involved in the control of arousal. Extracellular levels of acid /CO2 are fundamental physicochemical signals controlling wakefulness and breathing. Acidification excites orexine

Externí odkaz: https://doaj.org/article/524a40bcbe80466fbe76db872990c018

OLHA (N

Autor: Olga A, Sergeeva, Karolina, Mazur, David, Reiner-Link, Kiril, Lutsenko, Helmut L, Haas, Mercedes, Alfonso-Prieto, Holger, Stark

Publikováno v: Neuropharmacology. 215

Histaminergic (HA) neurons are located in the tuberomamillary nucleus (TMN) of the posterior hypothalamus, from where they project throughout the whole brain to control wakefulness. We examined the effects of N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5764d5da0fa00ebe3f68993f0fc5a89e
https://pubmed.ncbi.nlm.nih.gov/35750238

Histamine receptors in GtoPdb v.2021.3

Autor: Nigel P. Shankley, Hiroyuki Fukui, Steve Liu, C. Robin Ganellin, Pertti Panula, Robin L. Thurmond, Roland Seifert, Stephen J. Hill, Jean-Charles Schwartz, Roberto Levi, Rob Leurs, Henk Timmerman, J. Michael Young, Ralf Gutzmer, Holger Stark, Paul L. Chazot, Rebecca Hills, Helmut L. Haas, Marlon D. Cowart, Walter Schunack

Publikováno v: IUPHAR/BPS Guide to Pharmacology CITE. 2021

Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 173]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80]. The human and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e36a9ef171668170ae3aa6bcfacd20d2
https://doi.org/10.2218/gtopdb/f33/2021.3

Histamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Autor: Henk Timmerman, J. Michael Young, Ralf Gutzmer, Nigel P. Shankley, Jean-Charles Schwartz, Holger Stark, Rebecca Hills, Robin L. Thurmond, Roberto Levi, Helmut L. Haas, Hiroyuki Fukui, Walter Schunack, Steve Liu, Rob Leurs, Roland Seifert, Paul L. Chazot, C. Robin Ganellin, Stephen J. Hill, Pertti Panula, Marlon D. Cowart

Publikováno v: IUPHAR/BPS Guide to Pharmacology CITE. 2019

Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [75, 163]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [75]. The human and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::909fa860575554046685bc146f90b913
https://doi.org/10.2218/gtopdb/f33/2019.4

Schistosoma mansoni Egg-Released IPSE/alpha-1 Dampens Inflammatory Cytokine Responses via Basophil Interleukin (IL)-4 and IL-13

Autor: Gabriele Schramm, Michael J. Doenhoff, Katrin Knuhr, Sandra Nyenhuis, Kristina Langhans, Helmut L. Haas, Kerstin Viertmann, Anna Overgaard Kildemoes

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Knuhr, K, Langhans, K, Nyenhuis, S, Viertmann, K, Kildemoes, A O, Doenhoff, M, Haas, H & Schramm, G 2018, ' Schistosoma mansoni Egg-Released IPSE/alpha-1 Dampens Inflammatory Cytokine Responses via Basophil Interleukin (IL)-4 and IL-13 ', Frontiers in Immunology, vol. 9, 2293 . https://doi.org/10.3389/fimmu.2018.02293

Schistosomes control inflammation in their hosts via highly effective mechanisms such as induction of Tregs, Bregs, and alternatively activated macrophages (AAMs). Notably, IPSE/alpha-1, the major secretory product from Schistosoma mansoni eggs, trig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c764f04a862d2cb171d3bb4ebb9834ef
http://europepmc.org/articles/PMC6191518