Histamine receptors in GtoPdb v.2023.1

Autor: J. Michael Young, Henk Timmerman, Robin Thurmond, Holger Stark, Nigel P. Shankley, Roland Seifert, Jean-Charles Schwartz, Walter Schunack, Pertti Panula, Steve Liu, Roberto Levi, Rob Leurs, Rebecca Hills, Stephen J. Hill, Helmut L. Haas, Ralf Gutzmer, C. Robin Ganellin, Hiroyuki Fukui, Marlon Cowart, Paul Chazot

Publikováno v: IUPHAR/BPS Guide to Pharmacology CITE. 2023

Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 174]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80]. The human and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ab34122021ce28ae74c282dc7ff573b
https://doi.org/10.2218/gtopdb/f33/2023.1

OLHA (N-oleoylhistamine) modulates activity of mouse brain histaminergic neurons

Autor: Olga A. Sergeeva, Karolina Mazur, David Reiner-Link, Kiril Lutsenko, Helmut L. Haas, Mercedes Alfonso-Prieto, Holger Stark

Publikováno v: Neuropharmacology 215, 109167 (2022). doi:10.1016/j.neuropharm.2022.109167

Histaminergic (HA) neurons are located in the tuberomamillary nucleus (TMN) of the posterior hypothalamus, from where they project throughout the whole brain to control wakefulness. We examined the effects of Nα-oleoylhistamine (OLHA), a non-enzymat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b12a34dc75cf4618bf0f3e055ef6fb
https://juser.fz-juelich.de/record/908294

Taurine rescues hippocampal long-term potentiation from ammonia-induced impairment

Autor: Aisa N. Chepkova, Olga A. Sergeeva, Helmut L. Haas

Publikováno v: Neurobiology of Disease, Vol 23, Iss 3, Pp 512-521 (2006)

Hyperammonemia, a major pathophysiological factor in hepatic encephalopathy, impairs long-term potentiation (LTP) of synaptic transmission, a cellular model of learning and memory, in the hippocampus. We have now studied the protective action of taur

Externí odkaz: https://doaj.org/article/09592f400f1c4a8aad1815a2560c5080

Histamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Autor: Henk Timmerman, J. Michael Young, Ralf Gutzmer, Nigel P. Shankley, Jean-Charles Schwartz, Holger Stark, Rebecca Hills, Robin L. Thurmond, Roberto Levi, Helmut L. Haas, Hiroyuki Fukui, Walter Schunack, Steve Liu, Rob Leurs, Roland Seifert, Paul L. Chazot, C. Robin Ganellin, Stephen J. Hill, Pertti Panula, Marlon D. Cowart

Publikováno v: IUPHAR/BPS Guide to Pharmacology CITE. 2019

Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [75, 163]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [75]. The human and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::909fa860575554046685bc146f90b913
https://doi.org/10.2218/gtopdb/f33/2019.4

Schistosoma mansoni Egg-Released IPSE/alpha-1 Dampens Inflammatory Cytokine Responses via Basophil Interleukin (IL)-4 and IL-13

Autor: Gabriele Schramm, Michael J. Doenhoff, Katrin Knuhr, Sandra Nyenhuis, Kristina Langhans, Helmut L. Haas, Kerstin Viertmann, Anna Overgaard Kildemoes

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Knuhr, K, Langhans, K, Nyenhuis, S, Viertmann, K, Kildemoes, A O, Doenhoff, M, Haas, H & Schramm, G 2018, ' Schistosoma mansoni Egg-Released IPSE/alpha-1 Dampens Inflammatory Cytokine Responses via Basophil Interleukin (IL)-4 and IL-13 ', Frontiers in Immunology, vol. 9, 2293 . https://doi.org/10.3389/fimmu.2018.02293

Schistosomes control inflammation in their hosts via highly effective mechanisms such as induction of Tregs, Bregs, and alternatively activated macrophages (AAMs). Notably, IPSE/alpha-1, the major secretory product from Schistosoma mansoni eggs, trig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c764f04a862d2cb171d3bb4ebb9834ef
http://europepmc.org/articles/PMC6191518