Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Helmut J. Kolb"'
Autor:
Sabine Nedbal, Eckhard Wolf, Lutz Bünger, Martin W. Elmlinger, Andreas Hoeflich, Charlotte Bruley, Ulla Renne, Werner F. Blum, Helmut J. Kolb
Publikováno v:
General and Comparative Endocrinology. 136:248-259
Transgenic and knockout models have been used successfully in order to attribute specific functions to distinct growth factors. However, it is not clear which from the different IGF-components are actually altered when growth is affected. Furthermore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd4e7eeea302db8581fdff85fe5214b
https://doi.org/10.1016/j.ygcen.2003.12.019
https://doi.org/10.1016/j.ygcen.2003.12.019
Autor:
Martin Hrabé de Angelis, Edith Fuchs, Rudi Balling, Ingrid Renner-Müller, Helmut J. Kolb, Eckhard Wolf, Ottheinz Krebs, Birgit Rathkolb
Publikováno v:
Experimental Physiology. 85:635-643
The most important tool for obtaining insight into the function of genes is the use of mutant model organisms. Homologous recombination in embryonic stem cells allows the systematic production of mouse mutants for any gene that has been cloned. Gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7f4155aa8c98bbe964a6cf1c37143e4
https://doi.org/10.1111/j.1469-445x.2000.02094.x
https://doi.org/10.1111/j.1469-445x.2000.02094.x
Autor:
Birgit Rathkolb, Edith Fuchs, Helmut J. Kolb, Ingrid Renner-Müller, Ottheinz Krebs, Rudi Balling, Martin Hrabé de Angelis, Eckhard Wolf
Publikováno v:
Experimental Physiology. 85:635-643
The most important tool for obtaining insight into the function of genes is the use of mutant model organisms. Homologous recombination in embryonic stem cells allows the systematic production of mouse mutants for any gene that has been cloned. Gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49bec0b97857cc2bdf998764f276ce7
https://doi.org/10.1017/s0958067000020947
https://doi.org/10.1017/s0958067000020947
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 123:1-8
Extraembryonal degradation of yolk protein is necessary to provide the avian embryo with required free amino acids during early embryogenesis. Screening of proteolytic activity in different compartments of quail eggs revealed an increasing activity i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b3f1a622d7df3fffe1d8a95eb11ad4
https://doi.org/10.1016/s1095-6433(99)00031-8
https://doi.org/10.1016/s1095-6433(99)00031-8
Autor:
Meinhard Classen, Christian Prinz, Nina Neumayer, Sabine Mahr, Helmut J. Kolb, Wolfgang Schepp
Publikováno v:
Endocrinology. 139:4380-4390
Enterochromaffin-like (ECL) cells are histamine-containing endocrine cells in the gastric epithelium that show increased density during chronic atrophic gastritis. The current study determined cell number and apoptosis of isolated rat ECL cells in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b70dcd38930d2fa42b987c1066aaa20b
https://doi.org/10.1210/endo.139.10.6248
https://doi.org/10.1210/endo.139.10.6248
Autor:
Andreas Hoeflich, Pirchner F, Matthias M. Weber, Jürgen Föll, Helmut J. Kolb, Eckhard Wolf, Peter J. Schmidt, Oswald Rottmann
Publikováno v:
Scopus-Elsevier
Summary Mice investigated in this study were generated by selecting a sub-population of the NMRI out-bred stock (C), for high (H) or low (L) 8-week body weight. After 58 generations of selection, 8-week body weights of the sub-populations were marked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5da459ad594256367d8d7a057fe68a
https://doi.org/10.1016/s1096-6374(98)80101-9
https://doi.org/10.1016/s1096-6374(98)80101-9
Autor:
Hans Fritz, Helmut J. Kolb, Rainer Mentele, Josef Wittmann, Ennes A. Auerswald, Werner Machleidt, Bernd Gerhartz
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 118:159-166
Degradation of yolk protein is essential for the early development of the avian embryo. In Japanese quail (Coturnix coturnix japonica), proteolysis in the surrounding tissue of the yolk, the yolk-sac membrane, can be inhibited by class-specific inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2c92448433816dd4c7e774090f796f
https://doi.org/10.1016/s0305-0491(97)00034-5
https://doi.org/10.1016/s0305-0491(97)00034-5
Autor:
Wieland Kiess, P. Heinz-Erian, Werner F. Blum, Y. Yang, Gabriele Koepf, Wolfgang Rascher, Helmut J. Kolb, Andreas Hoeflich, S. Huber
Publikováno v:
Scopus-Elsevier
Local production of insulin-like growth factor (IGF)-binding proteins (IGFBP) determines the availability of the IGF to the cell and thus regulates IGF action. To find out whether specific patterns of IGFBP gene expression and IGFBP secretion were re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c604e356cf8a7e46101fa6e9eeb3611
https://doi.org/10.1152/ajpendo.1996.271.5.e922
https://doi.org/10.1152/ajpendo.1996.271.5.e922
Autor:
Stefan Huber, Wieland Kiess, Wolfgang Rascher, Gabriele Koepf, Yi Yang, Andreas Hoeflich, Helmut J. Kolb, Werner F. Blum
Publikováno v:
Scopus-Elsevier
Hoeflich A, Yang Y, Rascher W, Blum WF, Huber S, Koepf G, Kolb HJ, Kiess W. Coordinate expression of insulin-like growth factor II (IGF-II) and IGF-II/mannose-6-phosphate receptor mRNA and stable expression of IGF-I receptor mRNA during differentiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94bd79bbe26f769285a5049a8f65e5c
https://doi.org/10.1530/eje.0.1350049
https://doi.org/10.1530/eje.0.1350049
Publikováno v:
Molecular and Cellular Endocrinology. 101:141-150
The IGFs have been implicated in the development of the intestinal tract. We have studied the human colon carcinoma cell line CaCo-2 to gain more insight into the function of the IGFs in the gut. [125I]IGF-I and -II bound specifically to CaCo-2 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0597e171d69c8f50bc4db816f6bd3f
https://doi.org/10.1016/0303-7207(94)90228-3
https://doi.org/10.1016/0303-7207(94)90228-3