Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Helmut Ellemunter"'
Autor:
Teresa Fuchs, Manuela Zlamy, Thomas Zöggeler, Dorothea Appelt, Katharina Niedermayr, Anja Siedl, Verena Gasser, Johannes Eder, Helmut Ellemunter
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Background Cystic fibrosis (CF) is a genetic multisystem disorder. Inflammatory processes, which presumably begin early in infancy, play a crucial role in the progression of the disease. The detection of inflammatory biomarkers, especially i
Externí odkaz:
https://doaj.org/article/f81159436e84450898ebe060cf893459
Autor:
Giorgia Renga, Fiorella D’Onofrio, Marilena Pariano, Roberta Galarini, Carolina Barola, Claudia Stincardini, Marina M. Bellet, Helmut Ellemunter, Cornelia Lass-Flörl, Claudio Costantini, Valerio Napolioni, Allison K. Ehrlich, Cinzia Antognelli, Massimo Fini, Enrico Garaci, Emilia Nunzi, Luigina Romani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract The aromatic amino acid L-tryptophan (Trp) is essentially metabolized along the host and microbial pathways. While much is known about the role played by downstream metabolites of each pathways in intestinal homeostasis, their role in lung i
Externí odkaz:
https://doaj.org/article/55ef849205bf4431a7d35facb0df52e6
Autor:
Giorgia Renga, Fiorella D’Onofrio, Marilena Pariano, Roberta Galarini, Carolina Barola, Claudia Stincardini, Marina M. Bellet, Helmut Ellemunter, Cornelia Lass-Flörl, Claudio Costantini, Valerio Napolioni, Allison K. Ehrlich, Cinzia Antognelli, Massimo Fini, Enrico Garaci, Emilia Nunzi, Luigina Romani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/e48746aa645243f7ad232bb4f71c290e
Publikováno v:
Vaccines, Vol 12, Iss 1, p 98 (2024)
With the worldwide spread of SARS-CoV-2 disease, people with cystic fibrosis (CF), especially solid organ transplant recipients, have quickly been identified as a risk group for severe disease. Studies have shown low antibody response to SARS-CoV-2 v
Externí odkaz:
https://doaj.org/article/6b4cdab3478b4a31baedf5084afd9129
Autor:
Sivagurunathan Sutharsan, Stefanie Dillenhoefer, Matthias Welsner, Florian Stehling, Folke Brinkmann, Manuel Burkhart, Helmut Ellemunter, Anna-Maria Dittrich, Christina Smaczny, Olaf Eickmeier, Matthias Kappler, Carsten Schwarz, Sarah Sieber, Susanne Naehrig, Lutz Naehrlich, Klaus Tenbrock, Claus Pfannenstiel, Dirk Steffen, Jochen Meister, Britta Welzenbach, Anette Scharschinger, Markus Kratz, Maike Pincus, Tobias Tenenbaum, Mirjam Stahl, Kerstin Landwehr, Stefanie Dillenhöfer, Hans Kössel, Petra Kaiser, Manfred Käding, Simone Stolz, Stefan Blaas, Jutta Hammermann, Monika Gappa, Antje Schuster, Dana Spittel, Sabine Zirlik, Sabina Schmitt, Joachim Bargon, Malte Cremer, Sebastian Fähndrich, Andrea Heinzmann, Lutz Nährlich, Stefan Kuhnert, Sebastian Schmidt, Bettina Wollschläger, Anna Nolde, Inka Held, Wolfgang Kamin, Felix C. Ringshausen, Sabine Wege, Olaf Sommerburg, Norbert Geier, Sara Lisa Fleser, Heinrike Wilkens, Michael Lorenz, Paul Vöhringer, Martin Schebek, Christian Timke, Ingrid Bobis, Thomas Nüßlein, Doris Dieninghoff, Ernst Rietschel, Bastian Klinkhammer, Freerk Prenzel, Alexandra Wald, Axel Kempa, Eva Lücke, Ines Adams, Krystyna Poplawska, Simone Lehmkühler, Monika Bauck, Anne Pfülb, Rainald Fischer, Gudrun Schopper, Susanne Nährig, Matthias Griese, Jörg Grosse, Peter Küster, Birte KinderHolger Köster, Susanne Büsing, Margarethe Pohl, Andreas Artlich, Alexander Kiefer, Manfred Ballmann, Nikola Gjorgjevski, Markus A. Rose, Friederike Ruf, Rolf Mahlberg, Wolfgang Thomas, Ute Graepler, Sebastian Bode, hilipp Meyn, Josef Rosenecker, Cordula Koerner, Klaus-Michael Keller, Tina Teßmer, Helge Hebestreit, Gerhild Lohse
Publikováno v:
The Lancet Regional Health. Europe, Vol 32, Iss , Pp 100690- (2023)
Summary: Background: Treatment with elexacaftor/tezacaftor/ivacaftor (ETI) improves multiple clinical outcomes in people with cystic fibrosis (pwCF) with at least one F508del allele. This study evaluated the real-world impact of ETI on lung function,
Externí odkaz:
https://doaj.org/article/cb7f1132ad9145b4909f1a838def4b95
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Since the introduction of CFTR modulator therapies, longitudinal real-life data of lung clearance index (LCI) during treatment is scarce. In this single-centre, post-approval setting, we report data of 51 patients with different stages of lung diseas
Externí odkaz:
https://doaj.org/article/36aa1823e1084fc390ab518be19e881b
Publikováno v:
Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-6 (2022)
Abstract Background Previous reports have shown an increased number of colorectal cancers in patients with cystic fibrosis. We assessed the database of our cystic fibrosis center to identify patients with all kinds of cancer retrospectively. All pati
Externí odkaz:
https://doaj.org/article/bcec38cf38344b868505b4e28a934f5a
Autor:
Katharina Niedermayr, Verena Gasser, Claudia Rueckes-Nilges, Dorothea Appelt, Johannes Eder, Teresa Fuchs, Lutz Naehrlich, Helmut Ellemunter
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 13 (2022)
Cystic fibrosis (CF) is caused by two mutations in the Cystic Fibrosis Transmembrane Conductance Regulator ( CFTR ) gene. In the last years, drugs targeting the underlying protein defect like lumacaftor/ivacaftor (LUM/IVA) or tezacaftor/ivacaftor (TE
Externí odkaz:
https://doaj.org/article/f05904fd54214adb95e74855fdf01e3e
Publikováno v:
Vaccines, Vol 11, Iss 3, p 657 (2023)
People with Cystic Fibrosis (CF), especially solid organ transplant recipients, have been prioritized in the SARS-CoV-2 vaccination program. This study assesses antibody response of patients with CF who have undergone liver (CF-LI) or lung (CF-LU) tr
Externí odkaz:
https://doaj.org/article/627c8872cc7545ecb6f355e729abeb8e
Publikováno v:
Clinical Case Reports, Vol 10, Iss 2, Pp n/a-n/a (2022)
Abstract This study summarizes efficacy of ivacaftor treatment in 2 infants in a real‐world setting. A distinct decline of sweat chloride and lung clearance index plus increase in fecal elastase was seen. The results underline the early and sustain
Externí odkaz:
https://doaj.org/article/5a7d7f7e80874ba49a9542bdb80f0bdf