Zobrazeno 1 - 10
of 575
pro vyhledávání: '"Helmut E. Meyer"'
Autor:
Christian Mölleken, Maike Ahrens, Anders Schlosser, Julia Dietz, Martin Eisenacher, Helmut E. Meyer, Wolff Schmiegel, Uffe Holmskov, Christoph Sarrazin, Grith Lykke Sorensen, Barbara Sitek, Thilo Bracht
Publikováno v:
Clinical and Molecular Hepatology, Vol 25, Iss 1, Pp 42-51 (2019)
Background/Aims An estimated 80 million people worldwide are infected with viremic hepatitis C virus (HCV). Even after eradication of HCV with direct acting antivirals (DAAs), hepatic fibrosis remains a risk factor for hepatocarcinogenesis. Recently,
Externí odkaz:
https://doaj.org/article/0c37bf0820804bbabe6b3931107fbda2
Autor:
Nikolas Thomanek, Jan Arends, Claudia Lindemann, Katalin Barkovits, Helmut E. Meyer, Katrin Marcus, Franz Narberhaus
Publikováno v:
Frontiers in Microbiology, Vol 9 (2019)
Lipopolysaccharides (LPS) in the outer membrane of Gram-negative bacteria provide the first line of defense against antibiotics and other harmful compounds. LPS biosynthesis critically depends on LpxC catalyzing the first committed enzyme in this pro
Externí odkaz:
https://doaj.org/article/29f10851a17347619f806006e3603d43
Autor:
Anna-Kristin Ludwig, Kyra De Miroschedji, Thorsten R. Doeppner, Verena Börger, Johannes Ruesing, Vera Rebmann, Stephan Durst, Sören Jansen, Michel Bremer, Elmar Behrmann, Bernhard B. Singer, Holger Jastrow, Jan Dominik Kuhlmann, Fouzi El Magraoui, Helmut E. Meyer, Dirk M. Hermann, Bertram Opalka, Stefan Raunser, Matthias Epple, Peter A. Horn, Bernd Giebel
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
Extracellular vesicles (EVs) provide a complex means of intercellular signalling between cells at local and distant sites, both within and between different organs. According to their cell-type specific signatures, EVs can function as a novel class o
Externí odkaz:
https://doaj.org/article/818ba5492eb54a3a8ed20c14c4c09196
Autor:
Eva Maria Mandelkow, Eckhard Mandelkow, Jacek Biernat, Senthilvelrajan Kaniyappan, Helmut E. Meyer, Bettina Warscheid, Friedel Drepper
Publikováno v:
The Journal of Biological Chemistry
The journal of biological chemistry 295(52), 18213-18225 (2020). doi:10.1074/jbc.RA120.015882
The journal of biological chemistry 295(52), 18213-18225 (2020). doi:10.1074/jbc.RA120.015882
Abnormal changes of neuronal Tau protein, such as phosphorylation and aggregation, are considered hallmarks of cognitive deficits in Alzheimer's disease. Abnormal phosphorylation is thought to precede aggregation and therefore to promote aggregation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce3a62bef12462225900a48e190e4b1
http://europepmc.org/articles/PMC7939451
http://europepmc.org/articles/PMC7939451
Publikováno v:
Bioanalytik ISBN: 9783662617069
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c27f16ae4aa293895a96d001226eb52
https://doi.org/10.1007/978-3-662-61707-6_16
https://doi.org/10.1007/978-3-662-61707-6_16
Autor:
Christian Poulsen, Yusuf Akhter, Amy Hye‐Won Jeon, Gerold Schmitt‐Ulms, Helmut E Meyer, Anja Stefanski, Kai Stühler, Matthias Wilmanns, Young‐Hwa Song
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-9 (2010)
Abstract Mycobacteria use a unique system for covalently modifying proteins based on the conjugation of a small protein, referred to as prokaryotic ubiquitin‐like protein (PUP). In this study, we report a proteome‐wide analysis of endogenous pupy
Externí odkaz:
https://doaj.org/article/1e3255fd776f4025bd206adab5773334
Autor:
Ralf Erdmann, Alexander Hupperich, Daniel Schwerter, Thomas Mastalski, Bettina Warscheid, Harald W. Platta, Rebecca Brinkmeier, Fouzi El Magraoui, Helmut E. Meyer, Christofer Strehl, Wolfgang Girzalsky
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:199-213
Peroxisomal biogenesis depends on the correct import of matrix proteins into the lumen of the organelle. Most peroxisomal matrix proteins harbor the peroxisomal targeting-type 1 (PTS1), which is recognized by the soluble PTS1-receptor Pex5p in the cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153b2724fc6e4402583791fc200676d4
https://doi.org/10.1016/j.bbamcr.2018.11.002
https://doi.org/10.1016/j.bbamcr.2018.11.002
Autor:
Caroline May, Eckhard Nordhoff, Swaantje Casjens, Michael Turewicz, Martin Eisenacher, Ralf Gold, Thomas Brüning, Beate Pesch, Christian Stephan, Dirk Woitalla, Botond Penke, Tamás Janáky, Dezső Virók, László Siklós, Jozsef I Engelhardt, Helmut E Meyer
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89596 (2014)
Amyotrophic lateral sclerosis (ALS), the most common adult-onset motor neuron disorder, is characterized by the progressive and selective loss of upper and lower motor neurons. Diagnosis of this disorder is based on clinical assessment, and the avera
Externí odkaz:
https://doaj.org/article/d66aa02092b940ca9e65157f80c0ce06
Autor:
Fouzi El Magraoui, Andreas Schrötter, Rebecca Brinkmeier, Lena Kunst, Thomas Mastalski, Thorsten Müller, Katrin Marcus, Helmut E Meyer, Wolfgang Girzalsky, Ralf Erdmann, Harald W Platta
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105894 (2014)
Peroxisomal biogenesis is an ubiquitin-dependent process because the receptors required for the import of peroxisomal matrix proteins are controlled via their ubiquitination status. A key step is the monoubiquitination of the import receptor Pex5p by
Externí odkaz:
https://doaj.org/article/991ac96c7bcb418b91cd5b060bb26e73
Autor:
Caroline, May, Frederic, Brosseron, Kathy, Pfeiffer, Kristin, Fuchs, Helmut E, Meyer, Barbara, Sitek, Katrin, Marcus
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2228
Two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) is based on the combination of two orthogonal separation techniques. In the first dimension, proteins are separated by their isoelectric point, a technique known as isoelectric focusing (IE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be8aa3cbb5978c6e4708b38104130f5a
https://pubmed.ncbi.nlm.nih.gov/33950483
https://pubmed.ncbi.nlm.nih.gov/33950483