Výsledky vyhledávání - "Helminth Proteins/genetics"

Canine echinococcosis: genetic diversity of Echinococcus granulosus sensu stricto (s.s.) from definitive hosts

Autor: María Magdalena Munguía Reyes, David Jenkins, F M Elmestiri, A Al-Hindi, Philip S. Craig, Imad Buishi, Paul R. Torgerson, A A Eljaki, Andrew M. Griffiths, Wai San Lett, S Pointing, S Lahmar, M A Alrefadi, S A Engliez, Munehiro Okamoto, Belgees Boufana

Canids, particularly dogs, constitute the major source of cystic echinococcosis (CE) infection to humans, with the majority of cases being caused byEchinococcus granulosus(G1 genotype). Canine echinococcosis is an asymptomatic disease caused by adult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ace7e775b16a19ea49be52cf799fd8

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A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing

Autor: Raymond J. Pierce, Wolfgang Sippl, Julien Lancelot, Karin Schmidtkunz, Alokta Chakrabarti, Dina Robaa, Jelena Melesina, Tajith B. Shaik, Christophe Romier, Conrad V. Simoben, Manfred Jung, Srinivasaraghavan Kannan, Martin Marek

Publikováno v: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Molecules, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩
Molecules, Vol 23, Iss 3, p 566 (2018)
Molecules; Volume 23; Issue 3; Pages: 566
Molecules, MDPI, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩

International audience; A promising means in the search of new small molecules for the treatment of schistosomiasis (amongst other parasitic ailments) is by targeting the parasitic epigenome. In the present study, a docking based virtual screening pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c57756972e5c4439f4e393638be3994b
http://europepmc.org/articles/PMC6017931

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CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis

Autor: Jantsch-Plunger, V., Gönczy, P., Romano, A., Schnabel, H., Hamill, D., Schnabel, R., Hyman, A. A., Glotzer, M.

Publikováno v: The Journal of Cell Biology
Journal of Cell Biology, vol. 149, no. 7, pp. 1391-1404

During cytokinesis of animal cells, the mitotic spindle plays at least two roles. Initially, the spindle positions the contractile ring. Subsequently, the central spindle, which is composed of microtubule bundles that form during anaphase, promotes a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ff0ffa78a4d7cad40cd75f025ae47f5f
https://pubmed.ncbi.nlm.nih.gov/10871280

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OOC-3, a novel putative transmembrane protein required for establishment of cortical domains and spindle orientation in the P(1) blastomere of C. elegans embryos

Autor: Anthony A. Hyman, Silke Pichler, Andrei Pozniakowski, Pierre Gönczy, Heinke Schnabel, Ralf Schnabel, Anthony J. Ashford

Publikováno v: Europe PubMed Central
ResearcherID

Asymmetric cell divisions require the establishment of an axis of polarity, which is subsequently communicated to downstream events. During the asymmetric cell division of the P1 blastomere in C. elegans, establishment of polarity depends on the esta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d74b7e658f44d6159163f52f47e4afd
http://europepmc.org/abstract/med/10769231

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