Opposing roles of microRNA Argonautes during Caenorhabditis elegans aging

Autor: Jerry S. Chen, William P. Schreiner, Laura B. Chipman, Ian Nicastro, James P. Broughton, Amy E. Pasquinelli, Antti P. Aalto

Publikováno v: PLoS Genetics
PLoS Genetics, Vol 14, Iss 6, p e1007379 (2018)
Aalto, A P, Nicastro, I A, Broughton, J P, Chipman, L B, Schreiner, W P, Chen, J S & Pasquinelli, A E 2018, ' Opposing roles of microRNA Argonautes during Caenorhabditis elegans aging ', PLoS Genetics, vol. 14, no. 6, e1007379 . https://doi.org/10.1371/journal.pgen.1007379

Argonaute (AGO) proteins partner with microRNAs (miRNAs) to target specific genes for post-transcriptional regulation. During larval development in Caenorhabditis elegans, Argonaute-Like Gene 1 (ALG-1) is the primary mediator of the miRNA pathway, wh

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http://europepmc.org/articles/PMC6013023