Zobrazeno 1 - 10 of 2 878 pro vyhledávání: '"Helming L"'
1
Akademický článek
M9657 Is a Bispecific Tumor-Targeted Anti-CD137 Agonist That Induces MSLN-Dependent Antitumor Immunity without Liver Inflammation.
Autor: Xu C; Research Unit Oncology, EMD Serono, Billerica, Massachusetts., Zhou X; Research Unit Oncology, EMD Serono, Billerica, Massachusetts., Webb L; Research Unit Oncology, EMD Serono, Billerica, Massachusetts., Yalavarthi S; Research Unit Oncology, EMD Serono, Billerica, Massachusetts., Zheng W; Research Unit Oncology, EMD Serono, Billerica, Massachusetts., Saha S; Research Unit Oncology, EMD Serono, Billerica, Massachusetts., Schweickhardt R; Discovery and Development Technologies, EMD Serono, Billerica, Massachusetts., Soloviev M; Discovery and Development Technologies, EMD Serono, Billerica, Massachusetts., Jenkins MH; Research Unit Oncology, EMD Serono, Billerica, Massachusetts., Brandstetter S; The Healthcare Business of Merck KGaA, Darmstadt, Germany., Belousova N; Research Unit Oncology, EMD Serono, Billerica, Massachusetts., Alimzhanov M; Research Unit Oncology, EMD Serono, Billerica, Massachusetts., Rabinovich B; Research Unit Oncology, EMD Serono, Billerica, Massachusetts., Deshpande AM; Research Unit Oncology, EMD Serono, Billerica, Massachusetts., Brewis N; F-star Therapeutics, Cambridge, United Kingdom., Helming L; Research Unit Oncology, EMD Serono, Billerica, Massachusetts.
Publikováno v: Cancer immunology research [Cancer Immunol Res] 2024 Feb 02; Vol. 12 (2), pp. 195-213.
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2
Akademický článek
Development of a c-MET x CD137 bispecific antibody for targeted immune agonism in cancer immunotherapy.
Autor: Zhang H; Research Unit Oncology, EMD Serono Research Center, 45 Middlesex Turnpike, Billerica, MA 01821, USA., Wang Q; Research Unit Oncology, EMD Serono Research Center, 45 Middlesex Turnpike, Billerica, MA 01821, USA., Yalavarthi S; Research Unit Oncology, EMD Serono Research Center, 45 Middlesex Turnpike, Billerica, MA 01821, USA., Pekar L; Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Frankfurter Str. 250, 64293 Darmstadt, Germany., Shamnoski S; Research Unit Oncology, EMD Serono Research Center, 45 Middlesex Turnpike, Billerica, MA 01821, USA., Hu L; Research Unit Oncology, EMD Serono Research Center, 45 Middlesex Turnpike, Billerica, MA 01821, USA., Helming L; Research Unit Oncology, EMD Serono Research Center, 45 Middlesex Turnpike, Billerica, MA 01821, USA., Zielonka S; Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Frankfurter Str. 250, 64293 Darmstadt, Germany., Xu C; Research Unit Oncology, EMD Serono Research Center, 45 Middlesex Turnpike, Billerica, MA 01821, USA. Electronic address: Chunxiao.xu@emdserono.com.
Publikováno v: Cancer treatment and research communications [Cancer Treat Res Commun] 2024; Vol. 39, pp. 100805. Date of Electronic Publication: 2024 Mar 08.
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3
Akademický článek
High-Throughput Screening and Proteomic Characterization of Compounds Targeting Myeloid-Derived Suppressor Cells.
Autor: Krumm J; Chair of Proteomics and Bioanalytics, Technical University of Munich, Freising, Germany., Petrova E; Global Research & Development, Discovery and Development Technologies, Discovery Pharmacology, Healthcare Business of Merck KGaA, Darmstadt, Germany., Lechner S; Chair of Proteomics and Bioanalytics, Technical University of Munich, Freising, Germany., Mergner J; Chair of Proteomics and Bioanalytics, Technical University of Munich, Freising, Germany; Bavarian Center for Biomolecular Mass Spectrometry at Klinikum rechts der Isar (BayBioMS@MRI), Technical University of Munich, Munich, Germany., Boehm HH; Global Research & Development, TIP-Oncology & Immunooncology, Myeloid Cell Research, Healthcare Business of Merck KGaA, Darmstadt, Germany., Prestipino A; Global Research & Development, Discovery and Development Technologies, Discovery Pharmacology, Healthcare Business of Merck KGaA, Darmstadt, Germany., Steinbrunn D; OmicScouts GmbH, Freising, Germany., Deline ML; Chair of Molecular Nutritional Medicine, TUM School of Life Sciences, Technical University of Munich, Freising, Germany., Koetzner L; Global Research & Development, Discovery and Development Technologies, Global Medicinal Chemistry, Healthcare Business of Merck KGaA, Darmstadt, Germany., Schindler C; Global Research & Development, Discovery Technologies, Computational Chemistry & Biologics, Healthcare Business of Merck KGaA, Darmstadt, Germany., Helming L; Global Research & Development, TIP-Oncology & Immunooncology, Myeloid Cell Research, Healthcare Business of Merck KGaA, Darmstadt, Germany., Fromme T; Chair of Molecular Nutritional Medicine, TUM School of Life Sciences, Technical University of Munich, Freising, Germany; Else Kröner Fresenius Center for Nutritional Medicine, Technical University of Munich, Freising, Germany; ZIEL Institute for Food & Health, Technical University of Munich, Freising, Germany., Klingenspor M; Chair of Molecular Nutritional Medicine, TUM School of Life Sciences, Technical University of Munich, Freising, Germany; Else Kröner Fresenius Center for Nutritional Medicine, Technical University of Munich, Freising, Germany; ZIEL Institute for Food & Health, Technical University of Munich, Freising, Germany., Hahne H; OmicScouts GmbH, Freising, Germany., Pieck JC; Global Research & Development, Discovery and Development Technologies, Discovery Pharmacology, Healthcare Business of Merck KGaA, Darmstadt, Germany., Kuster B; Chair of Proteomics and Bioanalytics, Technical University of Munich, Freising, Germany; Bavarian Biomolecular Mass Spectrometry Center (BayBioMS), Technical University of Munich, Freising, Germany. Electronic address: kuster@tum.de.
Publikováno v: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2023 Sep; Vol. 22 (9), pp. 100632. Date of Electronic Publication: 2023 Aug 14.
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6
Akademický článek
Systemic Administration of a Site-Targeted Complement Inhibitor Attenuates Chronic Stress-Induced Social Behavior Deficits and Neuroinflammation in Mice.
Autor: Madeshiya, Amit Kumar1 (AUTHOR) amit.kgmu21@gmail.com, Quintanilla, Brandi1 (AUTHOR) cwhitehead1@augusta.edu, Whitehead, Carl1 (AUTHOR), Tomlinson, Stephen2,3 (AUTHOR), Pillai, Anilkumar1,4 (AUTHOR) anilkumar.r.pillai@uth.tmc.edu
Publikováno v: Cells (2073-4409). Dec2024, Vol. 13 Issue 23, p1988. 15p.
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7
Akademický článek
Unraveling Macrophage Polarization: Functions, Mechanisms, and "Double-Edged Sword" Roles in Host Antiviral Immune Responses.
Autor: Yao, Meng1,2 (AUTHOR) a13678602285@163.com, Li, Meilin1 (AUTHOR) m18037901611@163.com, Peng, Dingkun1 (AUTHOR) pengdk11@163.com, Wang, Yijing1 (AUTHOR) 15039269261@163.com, Li, Su1 (AUTHOR) lisu@caas.cn, Zhang, Ding2 (AUTHOR) bo_yang@sxau.edu.cn, Yang, Bo2 (AUTHOR), Qiu, Hua-Ji1 (AUTHOR) qiuhuaji@caas.cn, Li, Lian-Feng1,2 (AUTHOR) qiuhuaji@caas.cn
Publikováno v: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p12078. 24p.
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8
Akademický článek
Unraveling the Immune Web: Advances in SMI Capsular Fibrosis from Molecular Insights to Preclinical Breakthroughs.
Autor: Schoberleitner, Ines1,2 (AUTHOR), Faserl, Klaus3 (AUTHOR), Lackner, Michaela4 (AUTHOR), Coraça-Huber, Débora C.5 (AUTHOR), Augustin, Angela6 (AUTHOR), Imsirovic, Anja2 (AUTHOR), Sigl, Stephan2 (AUTHOR), Wolfram, Dolores2 (AUTHOR) dolores.wolfram@i-med.ac.at
Publikováno v: Biomolecules (2218-273X). Nov2024, Vol. 14 Issue 11, p1433. 34p.
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10
Akademický článek
Type 1 diabetes and parasite infection: An exploratory study in NOD mice.
Autor: Giraud, Emilie1 (AUTHOR), Fiette, Laurence2 (AUTHOR), Melanitou, Evie3 (AUTHOR) evie.melanitou@pasteur.fr
Publikováno v: PLoS ONE. 10/22/2024, Vol. 19 Issue 10, p1-28. 28p.
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