Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Helmi, Pett"'
Autor:
Patrick A. M. Jansen, Taco W. A. Kooij, Martijn W. Vos, Manuel Llinás, Floris P. J. T. Rutjes, Sergio Wittlin, Gabrielle A. Josling, Iñigo Angulo-Barturen, Stacy A. Reeves, Julie M. J. Verhoef, Karin M. J. Koolen, Erik L. Allman, Karen Miller, Helmi Pett, Suzanne Jackowski, Judith M. Bolscher, Robert W. Sauerwein, L. E. De Vries, María Belén Jiménez-Díaz, Richard H. Blaauw, Peter N. M. Botman, Graham P. Trevitt, Christien A. Beuckens-Schortinghuis, Brice Campo, Christian Scheurer, Sibylle Sax, Koen J. Dechering, Pedro H. H. Hermkens, Roger Bonnert, Christoph Fischli, Joost Schalkwijk
Publikováno v:
Science Translational Medicine. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6549a95b6758c0507a3f1f8b74eaf188
https://doi.org/10.1126/scitranslmed.abg8900
https://doi.org/10.1126/scitranslmed.abg8900
Autor:
Helmi Pett, Antti Sajantila, P. Vauhkonen, Jukka U. Palo, Jari Haukka, Ilkka Ojanperä, Anna-Liina Rahikainen, Mikko Niemi
Publikováno v:
International Journal of Legal Medicine. 133:353-363
Depression is known to be a risk factor for suicide. Currently, the most used antidepressants are selective serotonin reuptake inhibitors (SSRIs). Not all users, however, benefit from them. In such cases, treatment failure can be explained in part by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e397f4bf8a6cc5a6ac458510043781
https://doi.org/10.1007/s00414-018-1927-0
https://doi.org/10.1007/s00414-018-1927-0
Autor:
Patrick A. M. Jansen, Taco W. A. Kooij, Helmi Pett, Judith M. Bolscher, Suzanne Jackowski, Laura E. de Vries, María Belén Jiménez-Díaz, Brice Campo, Martijn W. Vos, Karin M. J. Koolen, Roger Bonnert, Stacy A. Reeves, Christoph Fischli, Christien A. Beuckens-Schortinghuis, Peter N. M. Botman, Koen J. Dechering, Manuel Llinás, Gabrielle A. Josling, Robert W. Sauerwein, Joost Schalkwijk, Julie M. J. Verhoef, Sergio Wittlin, Karen Miller, Pedro H. H. Hermkens, Graham P. Trevitt, Iñigo Angulo-Barturen, Erik L. Allman, Floris P. J. T. Rutjes, Richard H. Blaauw, Christian Scheurer, Sibylle Sax
Publikováno v:
Science Translational Medicine, 11(510)
Science Translational Medicine, 11, 510, pp. 1-16
Science Translational Medicine, 11, 1-16
Science Translational Medicine 11 (2019) 510
Science Translational Medicine, 11, 510, pp. 1-16
Science Translational Medicine, 11, 1-16
Science Translational Medicine 11 (2019) 510
Malaria eradication is critically dependent on new therapeutics that target resistant Plasmodium parasites and block transmission of the disease. Here, we report that pantothenamide bioisosteres were active against blood-stage Plasmodium falciparum p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef5f25c8bda84ba537ac40b18f93959
https://research.wur.nl/en/publications/antimalarial-pantothenamide-metabolites-target-acetyl-coenzyme-a-
https://research.wur.nl/en/publications/antimalarial-pantothenamide-metabolites-target-acetyl-coenzyme-a-
Autor:
Robert W. Sauerwein, Christoph Fischli, Suzanne Jackowski, Koen J. Dechering, Floris P. J. T. Rutjes, Martijn W. Vos, Christian Scheurer, Helmi Pett, Stacy A. Reeves, Sibylle Sax, Laura E. de Vries, Pedro H. H. Hermkens, Gabrielle A. Josling, Richard H. Blaauw, Sergio Wittlin, Erik L. Allman, Karin M. J. Koolen, Roger Bonnert, Christien A. Beuckens-Schortinghuis, Peter N. M. Botman, Joost Schalkwijk, Brice Campo, Karen Miller, Judith M. Bolscher, Patrick A. M. Jansen, Taco W. A. Kooij, Manuel Llinás, Graham P. Trevitt
Malaria eradication is critically dependent on novel drugs that target resistantPlasmodiumparasites and block transmission of the disease. Here we report the discovery of potent pantothenamide bioisosteres that are active against blood-stageP. falcip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a7559646b6be9035b4dd72ab909023
https://doi.org/10.1101/256669
https://doi.org/10.1101/256669
Autor:
Joost, Schalkwijk, Erik L, Allman, Patrick A M, Jansen, Laura E, de Vries, Julie M J, Verhoef, Suzanne, Jackowski, Peter N M, Botman, Christien A, Beuckens-Schortinghuis, Karin M J, Koolen, Judith M, Bolscher, Martijn W, Vos, Karen, Miller, Stacy A, Reeves, Helmi, Pett, Graham, Trevitt, Sergio, Wittlin, Christian, Scheurer, Sibylle, Sax, Christoph, Fischli, Iñigo, Angulo-Barturen, Mariá Belén, Jiménez-Diaz, Gabrielle, Josling, Taco W A, Kooij, Roger, Bonnert, Brice, Campo, Richard H, Blaauw, Floris P J T, Rutjes, Robert W, Sauerwein, Manuel, Llinás, Pedro H H, Hermkens, Koen J, Dechering
Publikováno v:
Science translational medicine. 11(510)
Malaria eradication is critically dependent on new therapeutics that target resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::841dc2b1d75efe5c50f2f7949ba194d8
https://pubmed.ncbi.nlm.nih.gov/33568524
https://pubmed.ncbi.nlm.nih.gov/33568524
Autor:
Sodiomon B. Sirima, Rob ter Heine, Daryl J. Murry, Helmi Pett, Bronner P. Gonçalves, Teun Bousema, Alfred B. Tiono, Chris Drakeley, Mikko Niemi
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, 61, 5, pp. pii: e02590-16-pii: e02590-16
Antimicrobial Agents and Chemotherapy, 61, pii: e02590-16-pii: e02590-16
Antimicrobial Agents and Chemotherapy, 61, 5, pp. pii: e02590-16-pii: e02590-16
Antimicrobial Agents and Chemotherapy, 61, pii: e02590-16-pii: e02590-16
Low-dose primaquine is recommended to prevent Plasmodium falciparum malaria transmission in areas threatened by artemisinin resistance and areas aiming for malaria elimination. Community treatment campaigns with artemisinin-based combination therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ff8fa68fce66d90f4d8d7a9b3bf6b2
Autor:
Sekouba Keita, Roly Gosling, Halimatou Diawara, Kjerstin Lanke, Helmi Pett, Fanta Koita, Alassane Dicko, Eugenie Poirot, François Nosten, Sekou F. Traore, Mikko Niemi, Almahamoudou Mahamar, Koualy Sanogo, Harouna M Soumare, Jimee Hwang, Ingrid Chen, Charles E. McCulloch, Teun Bousema, Ibrahima Baber, Joelle Brown
Publikováno v:
Lancet Infectious Diseases, 16, 6, pp. 674-84
The Lancet Infectious Diseases
Lancet Infectious Diseases, 16, 674-84
The Lancet Infectious Diseases
Lancet Infectious Diseases, 16, 674-84
Background Single low doses of primaquine, when added to artemisinin-based combination therapy, might prevent transmission of Plasmodium falciparum malaria to mosquitoes. We aimed to establish the activity and safety of four low doses of primaquine c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5dd3f572ab0e1d0460d850fa830f1b
http://hdl.handle.net/10138/224035
http://hdl.handle.net/10138/224035
Autor:
Alice C Eziefula, Alfred B. Tiono, Débé Siaka, Alphonse Ouedraogo, Kjerstin Lanke, Edith C. Bougouma, Helmi Pett, Issa Nebie, Wamdaogo M. Guelbeogo, Amidou Diarra, John S. Bradley, Teun Bousema, Sodiomon B. Sirima, Bronner P. Gonçalves, Chris Drakeley
Publikováno v:
BMC Medicine
BMC Medicine, 14, 1, pp. 40
BMC Medicine, 14, 40
BMC Medicine, 14, 1, pp. 40
BMC Medicine, 14, 40
Background A single low dose (0.25 mg/kg) of primaquine is recommended as a gametocytocide in combination with artemisinin-based combination therapies for Plasmodium falciparum but its effect on post-treatment gametocyte circulation and infectiousnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1cb0c00ee435fb3be64cccf2c8ee16
https://researchonline.lshtm.ac.uk/id/eprint/2536574/1/12916_2016_581_MOESM3_ESM.pdf
https://researchonline.lshtm.ac.uk/id/eprint/2536574/1/12916_2016_581_MOESM3_ESM.pdf
Autor:
Bruce M. Psaty, J. C. Bis, Olaf H. Klungel, Anke-Hilse Maitland-van der Zee, Nicole L. Glazer, Bas J M Peters, Helmi Pett, Bruno H. Stricker, Anthonius de Boer, Kerri L. Wiggins
Publikováno v:
Atherosclerosis, 217(2), 458-464. Elsevier Ireland Ltd
Genetic variability has been shown to affect statin responsiveness. Participants from the Utrecht Cardiovascular Pharmacogenetics (UCP) studies were enrolled from a population-based registry of pharmacy records linked to hospital discharge records (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84dc521e780e798b8fc7b318f1e6fb0a
https://pure.eur.nl/en/publications/8dd2d5b9-baca-4e65-ae84-1d6fb925b785
https://pure.eur.nl/en/publications/8dd2d5b9-baca-4e65-ae84-1d6fb925b785
Autor:
Kjerstin Lanke, Teun Bousema, Helmi Pett, Lynn Grignard, Colin J. Sutherland, Amrish Baidjoe, Chris Drakeley, Fitsum G. Tadesse, Hassen Mamo, Thomas A. Hall
Publikováno v:
Malaria Journal
Malaria Journal, 14, pp. 303
Malaria Journal, 14, 303
Malaria Journal, 14, pp. 303
Malaria Journal, 14, 303
BACKGROUND: Motivated by the success in malaria control that was documented over the last decade Ethiopia is aiming at malaria elimination by 2020 in selected districts. It is currently unknown if asymptomatic, submicroscopic malaria parasite carriag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ba70e092d524dfe6d6b6ef179f40a5
http://europepmc.org/articles/PMC4524028
http://europepmc.org/articles/PMC4524028