Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Helmar C. Lehmann"'
Autor:
René Günther, Claudia Diana Wurster, Svenja Brakemeier, Alma Osmanovic, Olivia Schreiber-Katz, Susanne Petri, Zeljko Uzelac, Miriam Hiebeler, Simone Thiele, Maggie C. Walter, Markus Weiler, Tobias Kessler, Maren Freigang, Hanna Sophie Lapp, Isabell Cordts, Paul Lingor, Marcus Deschauer, Andreas Hahn, Kyriakos Martakis, Robert Steinbach, Benjamin Ilse, Annekathrin Rödiger, Julia Bellut, Julia Nentwich, Daniel Zeller, Mohamad Tareq Muhandes, Tobias Baum, Jan Christoph Koch, Bertold Schrank, Sophie Fischer, Andreas Hermann, Christoph Kamm, Steffen Naegel, Alexander Mensch, Markus Weber, Christoph Neuwirth, Helmar C. Lehmann, Gilbert Wunderlich, Christian Stadler, Maike Tomforde, Annette George, Martin Groß, Astrid Pechmann, Janbernd Kirschner, Matthias Türk, Mareike Schimmel, Günther Bernert, Pascal Martin, Christian Rauscher, Gerd Meyer zu Hörste, Petra Baum, Wolfgang Löscher, Marina Flotats-Bastardas, Cornelia Köhler, Kristina Probst-Schendzielorz, Susanne Goldbach, Ulrike Schara-Schmidt, Wolfgang Müller-Felber, Hanns Lochmüller, Otgonzul von Velsen, Christoph Kleinschnitz, Albert C. Ludolph, Tim Hagenacker
Publikováno v:
The Lancet Regional Health. Europe, Vol 39, Iss , Pp 100862- (2024)
Summary: Background: Evidence for the efficacy of nusinersen in adults with 5q-associated spinal muscular atrophy (SMA) has been demonstrated up to a period of 16 months in relatively large cohorts but whereas patients reach a plateau over time is st
Externí odkaz:
https://doaj.org/article/290d74c1de7d42b58be5fe3b14b68827
Autor:
Felix Kohle, Robin Ackfeld, Franziska Hommen, Ines Klein, Martin K. R. Svačina, Christian Schneider, Gereon R. Fink, Mohammed Barham, David Vilchez, Helmar C. Lehmann
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background Autoimmune neuropathies can result in long-term disability and incomplete recovery, despite adequate first-line therapy. Kinesin-5 inhibition was shown to accelerate neurite outgrowth in different preclinical studies. Here, we eva
Externí odkaz:
https://doaj.org/article/7e8462d3a78c4041824d1c987335394b
Publikováno v:
Neurological Research and Practice, Vol 4, Iss 1, Pp 1-7 (2022)
Abstract Background No controlled studies for non-systemic vasculitic neuropathy treatment exist (NSVN). We compared the treatment response to induction therapy commonly used in clinical practice in NSVN. Methods In this retrospective single-center s
Externí odkaz:
https://doaj.org/article/32fff4db7e984fd99dc23b2fdc555a80
Autor:
Nicolai B. Grether, Felix Napravnik, Thomas Imhof, Reinhold P. Linke, Jan H. Bräsen, Jessica Schmitz, Maike Dohrn, Christian Schneider, Martin K. R. Svačina, Jörg Stetefeld, Manuel Koch, Helmar C. Lehmann
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 8, Pp 1252-1263 (2022)
Abstract Objective Hereditary transthyretin‐mediated amyloidosis is a treatable condition caused by amyloidogenic variants in the transthyretin‐gene resulting in severe peripheral neuropathy or cardiomyopathy. Only about a third of over 130 known
Externí odkaz:
https://doaj.org/article/9256e40912be45d381aff1bc160d6894
Autor:
Fiona Streckmann, Maryam Balke, Guido Cavaletti, Alexandra Toscanelli, Wilhelm Bloch, Bernhard F. Décard, Helmar C. Lehmann, Oliver Faude
Publikováno v:
Current Issues in Sport Science, Vol 8, Iss 2 (2023)
Introduction Neuropathies are a prevalent, heterogeneous group of diseases of the peripheral nervous system. Symptoms are often debilitating, difficult to treat, and usually become chronic. Not only do they diminish patients’ quality of life, bu
Externí odkaz:
https://doaj.org/article/9f95f2764d774b68b33b3622a51db9cf
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Despite advances in the treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and other common autoimmune neuropathies (AN), still-many patients with these diseases do not respond satisfactorily to the available treatments. Re
Externí odkaz:
https://doaj.org/article/a8e12a7b62044df4b522c8ebccfad6de
Autor:
Ines Klein, Janne Boenert, Felix Lange, Britt Christensen, Meike K. Wassermann, Martin H. J. Wiesen, Daniel Navin Olschewski, Monika Rabenstein, Carsten Müller, Helmar C. Lehmann, Gereon Rudolf Fink, Michael Schroeter, Maria Adele Rueger, Sabine Ulrike Vay
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Glia are critical players in defining synaptic contacts and maintaining neuronal homeostasis. Both astrocytes as glia of the central nervous system (CNS), as well as satellite glial cells (SGC) as glia of the peripheral nervous system (PNS), intimate
Externí odkaz:
https://doaj.org/article/cc2485729e3f4e83a3ff53a55ad567c3
Autor:
Ines Klein, Jörg Isensee, Martin H. J. Wiesen, Thomas Imhof, Meike K. Wassermann, Carsten Müller, Tim Hucho, Manuel Koch, Helmar C. Lehmann
Publikováno v:
Cells, Vol 12, Iss 9, p 1249 (2023)
Peripheral neuropathy is a common side effect of cancer treatment with paclitaxel. The mechanisms by which paclitaxel is transported into neurons, which are essential for preventing neuropathy, are not well understood. We studied the uptake mechanism
Externí odkaz:
https://doaj.org/article/ea8159b8f82d4bff9777993fe6df54a1
Publikováno v:
Neurological Research and Practice, Vol 2, Iss 1, Pp 1-7 (2020)
Abstract Introduction Peripheral neuropathy represents a spectrum of diseases with different etiologies. The most common causes are diabetes, exposure to toxic substances including alcohol and chemotherapeutics, immune-mediated conditions, and gene m
Externí odkaz:
https://doaj.org/article/4611d53ed1c14f749bcb020f37b6a605
Autor:
Jonas Graf, Christian J. Hartmann, Helmar C. Lehmann, Carolin Otto, Ortwin Adams, Michael Karenfort, Christian Schneider, Klemens Ruprecht, Hans Martin Bosse, Sabine Diedrich, Sindy Böttcher, Alfons Schnitzler, Hans-Peter Hartung, Orhan Aktas, Philipp Albrecht
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Aseptic meningitis epidemics may pose various health care challenges. Methods We describe the German enterovirus meningitis epidemics in the university hospital centers of Düsseldorf, Cologne and Berlin between January 1st and De
Externí odkaz:
https://doaj.org/article/ea05658e27b64de69c6e4db6c849fbf6