Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Helmar C Lehmann"'
Publikováno v:
Neurological Research and Practice, Vol 6, Iss 1, Pp 1-4 (2024)
Abstract Guillain-Barré syndrome is the most common acute inflammatory demyelinating peripheral nerve condition. Occasionally, other autoimmune conditions can mimic Guillain-Barré syndrome but may require different diagnostic workup and treatment.
Externí odkaz:
https://doaj.org/article/521532a00170449e9096356ac1129f48
Autor:
Gerd Meyer zu Hörste, Anne K Mausberg, Johanna I Müller, Helmar C Lehmann, Stefan Löber, Peter Gmeiner, Hans-Peter Hartung, Olaf Stüve, Carsten Korth, Bernd C Kieseier
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21223 (2011)
Activation of inflammatory cells is central to the pathogenesis of autoimmune demyelinating diseases of the peripheral nervous system. The novel chimeric compound quinpramine--generated from imipramine and quinacrine--redistributes cholesterol rich m
Externí odkaz:
https://doaj.org/article/c25d308f220f4236916dec59160e4b9f
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e27067 (2011)
Guillain-Barré syndrome (GBS) is a monophasic immune neuropathic disorder in which a significant proportion of patients have incomplete recovery. The patients with incomplete recovery almost always have some degree of failure of axon regeneration an
Externí odkaz:
https://doaj.org/article/ce3a20bf49a14898bcbb9f8b0836750c
Autor:
Anne K Mausberg, Gerd Meyer Zu Hörste, Thomas Dehmel, Mark Stettner, Helmar C Lehmann, Kazim A Sheikh, Bernd C Kieseier
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26280 (2011)
Erythropoietin (EPO) is a pleiotropic cytokine originally identified for its role in erythropoiesis. In addition, in various preclinical models EPO exhibited protective activity against tissue injury. There is an urgent need for potent treatments of
Externí odkaz:
https://doaj.org/article/a62e9ee4340241b7bfe9ac44e38eee13
Autor:
René Günther, Claudia Diana Wurster, Svenja Brakemeier, Alma Osmanovic, Olivia Schreiber-Katz, Susanne Petri, Zeljko Uzelac, Miriam Hiebeler, Simone Thiele, Maggie C. Walter, Markus Weiler, Tobias Kessler, Maren Freigang, Hanna Sophie Lapp, Isabell Cordts, Paul Lingor, Marcus Deschauer, Andreas Hahn, Kyriakos Martakis, Robert Steinbach, Benjamin Ilse, Annekathrin Rödiger, Julia Bellut, Julia Nentwich, Daniel Zeller, Mohamad Tareq Muhandes, Tobias Baum, Jan Christoph Koch, Bertold Schrank, Sophie Fischer, Andreas Hermann, Christoph Kamm, Steffen Naegel, Alexander Mensch, Markus Weber, Christoph Neuwirth, Helmar C. Lehmann, Gilbert Wunderlich, Christian Stadler, Maike Tomforde, Annette George, Martin Groß, Astrid Pechmann, Janbernd Kirschner, Matthias Türk, Mareike Schimmel, Günther Bernert, Pascal Martin, Christian Rauscher, Gerd Meyer zu Hörste, Petra Baum, Wolfgang Löscher, Marina Flotats-Bastardas, Cornelia Köhler, Kristina Probst-Schendzielorz, Susanne Goldbach, Ulrike Schara-Schmidt, Wolfgang Müller-Felber, Hanns Lochmüller, Otgonzul von Velsen, Christoph Kleinschnitz, Albert C. Ludolph, Tim Hagenacker
Publikováno v:
The Lancet Regional Health. Europe, Vol 39, Iss , Pp 100862- (2024)
Summary: Background: Evidence for the efficacy of nusinersen in adults with 5q-associated spinal muscular atrophy (SMA) has been demonstrated up to a period of 16 months in relatively large cohorts but whereas patients reach a plateau over time is st
Externí odkaz:
https://doaj.org/article/290d74c1de7d42b58be5fe3b14b68827
Autor:
Felix Kohle, Robin Ackfeld, Franziska Hommen, Ines Klein, Martin K. R. Svačina, Christian Schneider, Gereon R. Fink, Mohammed Barham, David Vilchez, Helmar C. Lehmann
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background Autoimmune neuropathies can result in long-term disability and incomplete recovery, despite adequate first-line therapy. Kinesin-5 inhibition was shown to accelerate neurite outgrowth in different preclinical studies. Here, we eva
Externí odkaz:
https://doaj.org/article/7e8462d3a78c4041824d1c987335394b
Autor:
Fiona Streckmann, Maryam Balke, Guido Cavaletti, Alexandra Toscanelli, Wilhelm Bloch, Bernhard F. Décard, Helmar C. Lehmann, Oliver Faude
Publikováno v:
Current Issues in Sport Science, Vol 8, Iss 2 (2023)
Introduction Neuropathies are a prevalent, heterogeneous group of diseases of the peripheral nervous system. Symptoms are often debilitating, difficult to treat, and usually become chronic. Not only do they diminish patients’ quality of life, bu
Externí odkaz:
https://doaj.org/article/9f95f2764d774b68b33b3622a51db9cf
Autor:
Ines Klein, Jörg Isensee, Martin H. J. Wiesen, Thomas Imhof, Meike K. Wassermann, Carsten Müller, Tim Hucho, Manuel Koch, Helmar C. Lehmann
Publikováno v:
Cells, Vol 12, Iss 9, p 1249 (2023)
Peripheral neuropathy is a common side effect of cancer treatment with paclitaxel. The mechanisms by which paclitaxel is transported into neurons, which are essential for preventing neuropathy, are not well understood. We studied the uptake mechanism
Externí odkaz:
https://doaj.org/article/ea8159b8f82d4bff9777993fe6df54a1
Autor:
Christian Schneider, Meike K. Wassermann, Martin K. R. Svačina, Gilbert Wunderlich, Gereon R. Fink, Helmar C. Lehmann
Publikováno v:
Muscle & Nerve. 67:474-480
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df2ca8cb1a0b0dfb83456dbdb5d1cf90
https://doi.org/10.1002/mus.27813
https://doi.org/10.1002/mus.27813
Autor:
Fiona Streckmann, Maryam Balke, Helmar C. Lehmann, Vanessa Rustler, Christina Koliamitra, Thomas Elter, Michael Hallek, Michael Leitzmann, Tilman Steinmetz, Petra Heinen, Freerk T. Baumann, Wilhelm Bloch
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Chemotherapy-induced peripheral neuropathy (CIPN) is a common and clinically relevant side effect of chemotherapy. Approximately 50% of all leukemia, lymphoma, colorectal- and breast cancer patients are affected. CIPN is induced b
Externí odkaz:
https://doaj.org/article/89cb986465bb4e0d99c3c519fcf8e016