Výsledky vyhledávání - "Helma W. Vos"

Aerosol measles vaccination in macaques: Preclinical studies of immune responses and safety

Autor: Selma Yüksel, José L. Valdespino, Geert van Amerongen, Phil Minor, John V. Bennett, Mark J. Papania, Helma W. Vos, Albert D. M. E. Osterhaus, Jorge Fernandez de Castro, Rik L. de Swart, Clyde Witham, Thijs Kuiken

Publikováno v: Vaccine, 24(40-41), 6424-6436. Elsevier

The comparative efficacy and safety of measles vaccination via the aerosol route versus subcutaneous injection has not been fully resolved. We vaccinated cynomolgus monkeys (Macaca fascicularis) with the live-attenuated Edmonston-Zagreb measles virus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4940c545cbe04e0b962a0878ff429f2
https://doi.org/10.1016/j.vaccine.2006.05.125

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Measles virus protein-specific IgM, IgA, and IgG subclass responses during the acute and convalescent phase of infection

Autor: H.S. El Mubarak, R.L. de Swart, Salah A. Ibrahim, Maowia M. Mukhtar, T.F. Wild, A.D.M.E. Osterhaus, Omer Allagabo Omer Mustafa, Helma W. Vos

Publikováno v: Journal of Medical Virology, 72(2), 290-298. Wiley-Liss Inc.

The availability of new generation serological assays allowed re-evaluation of the antibody response to measles virus. IgM, IgA, total IgG, and IgG subclass responses were studied to the three major immunogenic measles virus proteins: the fusion prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d976bf5ca7dd31309d29a21a349eb3a
https://hdl.handle.net/1765/63981

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Genetic characterization of wild-type measles viruses circulating in suburban Khartoum, 1997–2000

Autor: A.D.M.E. Osterhaus, M. W. G. van de Bildt, Omer Allagabo Omer Mustafa, Salah A. Ibrahim, Helma W. Vos, Maowia M. Mukhtar, A.M. El Hassan, Arno C. Andeweg, H.S. El Mubarak, R.L. de Swart

Publikováno v: Journal of General Virology. 83:1437-1443

Measles remains endemic in many East African countries, where it is often associated with high morbidity and mortality. We collected clinical specimens from Sudanese measles patients between July 1997 and July 2000. Sequencing of the 3′ 456 nucleot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71cfbfae8fa73996cd658d0dc206434
https://doi.org/10.1099/0022-1317-83-6-1437

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Priming of measles virus-specific humoral- and cellular-immune responses in macaques by DNA vaccination

Autor: Helma W. Vos, Albert D. M. E. Osterhaus, Koert J. Stittelaar, Rik L. de Swart, T. Fabian Wild, Geert van Amerongen, Nathalie Sixt

Publikováno v: Vaccine, 20. Elsevier

Although the currently used live attenuated measles vaccines are safe and effective, they are dependent on cold chain maintenance and are often ineffective in young infants due to interference by maternal antibody. Therefore, besides vector-based vac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97339f81b6b3875ee72c16e89480fd38
https://doi.org/10.1016/s0264-410x(02)00048-8

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Immunization of macaques with formalin-inactivated respiratory syncytial virus (RSV) induces Interleukin-13 associated hypersensitivity to subsequent RSV infection

Autor: Helma W. Vos, Bernadette G. van den Hoogen, Herman J. Neijens, H.H. Timmerman, Albert D. M. E. Osterhaus, Geert van Amerongen, Arno C. Andeweg, Rik L. de Swart, Thijs Kuiken

Publikováno v: Journal of Virology, 76(22), 11561-11569. American Society for Microbiology
Journal of Virology

Respiratory syncytial virus (RSV) is a major cause of severe respiratory disease in infants and the elderly. RSV vaccine development has been hampered by results of clinical trials in the 1960s, when formalin-inactivated whole-RSV preparations adjuva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec805944c6a5eb7f4ca3027b6bdb892
https://hdl.handle.net/1765/54234

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Safety of modified vaccinia virus Ankara (MVA) in immune-suppressed macaques

Autor: Pim van Schalkwijk, Thijs Kuiken, Hubert G. M. Niesters, Linda S. Wyatt, Bernard Moss, Helma W. Vos, Albert D. M. E. Osterhaus, Koert J. Stittelaar, Rik L. de Swart, Geert van Amerongen, Theo H. van der Kwast

Publikováno v: Vaccine, 19, 3700-3709. Elsevier

Modified vaccinia virus Ankara (MVA)-based recombinant viruses have been shown to be potent vaccine candidates for several infectious and neoplastic diseases. Since a major application of these live, replication-deficient vectors would be their use i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f69b6521da587469c117288e1971fd
https://doi.org/10.1016/s0264-410x(01)00075-5

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Evaluation of different measles IgG assays based on recombinant proteins using a panel of low-titre sera

Autor: Fabienne B. Bouche, R.L. de Swart, Claude P. Muller, Helma W. Vos, Francois Schneider, A.D.M.E. Osterhaus, H.K Hartter, F Hanses

Publikováno v: Journal of Virological Methods, 84, 191-200. Elsevier

During the WHO campaign to eradicate measles, accurate discrimination between immune and non-immune individuals will become increasingly important. Due to waning immunity in vaccinated populations, the performance of a measles IgG assay depends mainl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04108f466630036679dea0a2903c91f
https://doi.org/10.1016/s0166-0934(99)00143-3

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Protective immunity in macaques vaccinated with a modified vaccinia virus Ankara-based measles virus vaccine in the presence of passively acquired antibodies

Autor: Bernard Moss, Geert van Amerongen, Robert S. van Binnendijk, Helma W. Vos, Albert D. M. E. Osterhaus, Koert J. Stittelaar, Linda S. Wyatt, Jan Groen, Shmuel Rozenblatt, Rik L. de Swart

Publikováno v: Journal of Virology, 74(9), 4236-4243. American Society for Microbiology

Recombinant modified vaccinia virus Ankara (MVA), encoding the measles virus (MV) fusion (F) and hemagglutinin (H) (MVA-FH) glycoproteins, was evaluated in an MV vaccination-challenge model with macaques. Animals were vaccinated twice in the absence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f452c774bdd5eacb195f1f27148a04c
https://pure.eur.nl/en/publications/206b6d8a-35af-4484-83de-cba8858dd74e

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Autor: Helma W. Vos, Timm C. Harder, R.L. de Swart, A.D.M.E. Osterhaus

Publikováno v: Veterinary Record. 140:500-503

The prevalence and clinical signs of phocid herpesvirus type-1 (PhHV-1) infections among harbour seals (Phoca vitulina) in a seal rehabilitation centre in the Netherlands were monitored between June and September 1993 and 1994 when 34 and 36 seals, r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e84b1f40b0ea063f886722b4dc78ddf8
https://doi.org/10.1136/vr.140.19.500

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Canine distemper virus from diseased large felids: biological properties and phylogenetic relationships

Autor: Claes Örvell, Thomas Barrett, Kees H.J. Siebelink, Marcel Kenter, Timm C. Harder, G. van Amerongen, Helma W. Vos, Willem Huisman, Max J. G. Appel, A.D.M.E. Osterhaus

Publikováno v: Journal of General Virology. 77:397-405

Specific pathogen free (SPF) domestic cats were inoculated with tissue homogenate obtained from a Chinese leopard (Panthera pardus japonensis) that had died in a North American zoo from a natural infection with canine distemper virus (CDV). The cats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c7db699bd1cc29d08904fddf7db9ff
https://doi.org/10.1099/0022-1317-77-3-397

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