Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Helma Antony"'
Publikováno v:
Biomolecules, Vol 5, Iss 3, Pp 1697-1716 (2015)
α-Synuclein inclusion bodies are a pathological hallmark of several neurodegenerative diseases, including Parkinson’s disease, and contain aggregated α-synuclein and a variety of recruited factors, including protein chaperones, proteasome compone
Externí odkaz:
https://doaj.org/article/e266264ef1ff4cf795f192baa1a09e11
Autor:
Helma Antony, Alanna E. Sorenson, Samuel P. Askin, Rohan A. Davis, Patrick M. Schaeffer, Morgane J. J. Moreau, Thomas E. H. Bond
Publikováno v:
Chemical Communications. 54:1738-1741
High-throughput differential scanning fluorimetry of GFP-tagged proteins (HT-DSF-GTP) was applied for the identification of novel enzyme inhibitors acting by a mechanism termed: selective protein unfolding (SPU). Four different protein targets were i
Autor:
Ian Macreadie, Peter I. Macreadie, J.N. Varghese, Lynne J. Waddington, Helma Antony, Jo Caine, Sonia E. Sankovich
Publikováno v:
FEMS Yeast Research. 7:1230-1236
The 42 amino acid Alzheimer's Abeta peptide is involved in the progression of Alzheimer's disease. Here we describe the effects of intracellular Abeta, produced through its attachment to either end of a green fluorescent protein, in yeast. Cells prod
Publikováno v:
Current cancer drug targets. 13(8)
Prions are renowned for their role in neurodegenerative diseases in humans and animals. These are manifested as transmissible spongiform encephalopathies (TSEs) that result from the conversion of the normal glycosylphosphatidylinositol (GPI) anchored
Autor:
Ming Q. Wei, Alan L. Munn, Kum Kum Khanna, Adrian P. Wiegmans, Yury O. Chernoff, Helma Antony
Publikováno v:
Cancer metastasis reviews. 31(1-2)
Inherited mutations are known to cause familial cancers. However, the cause of sporadic cancers, which likely represent the majority of cancers, is yet to be elucidated. Sporadic cancers contain somatic mutations (including oncogenic mutations), howe
Autor:
Ian Macreadie, Helma Antony
Publikováno v:
Handbook of Behavior, Food and Nutrition ISBN: 9780387922706
Copper is an essential trace element. It is a component of a number of enzymes involved in functions that are vital for cells. Without copper, cell growth and survival are not maintained. Copper’s importance applies not only to human health, but to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c033c2d02cf87a9f80dbab1b7d35824
https://doi.org/10.1007/978-0-387-92271-3_150
https://doi.org/10.1007/978-0-387-92271-3_150
Autor:
Helma Antony, Patrick M. Schaeffer
Publikováno v:
The Analyst. 138:6073
Influenza is a viral pandemic that affects millions of people worldwide. Seasonal variations due to genetic shuffling and antigenic drifts in the influenza viruses have necessitated continual updating of therapeutics. The growing resistance to curren