Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Heller GT"'
Autor:
Perni, M, Flagmeier, P, Limbocker, R, Cascella, R, Aprile, Fa, Galvagnion, C, Heller, Gt, Meisl, G, Chen, Sw, Kumita, Jr, Challa, Pk, Kirkegaard, Jb, Cohen, Sia, Mannini, B, Barbut, D, Nollen, Eaa, Cecchi, C, Cremades, N, Knowles, Tpj, Chiti, F, Zasloff, M, Vendruscolo, M, Dobson, Cm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______310::643934268520e9e7d9e32fb2a8239319
http://hdl.handle.net/2158/1132660
http://hdl.handle.net/2158/1132660
Approximately one-third of the human proteome is made up of proteins that are entirely disordered or that contain extended disordered regions. Although these disordered proteins are closely linked with many major diseases, their binding mechanisms wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::728272462db78e88dd96a0e89eefb9a7
Autor:
Pettitt AJ; Department of Structural and Molecular Biology, Division of Biosciences, London, United Kingdom; Department of Engineering, Faculty of Natural, Mathematical and Engineering Sciences, King's College London, London, United Kingdom; The Francis Crick Institute, London, United Kingdom., Shukla VK; Department of Structural and Molecular Biology, Division of Biosciences, London, United Kingdom; The Francis Crick Institute, London, United Kingdom., Figueiredo AM; Department of Structural and Molecular Biology, Division of Biosciences, London, United Kingdom., Newton LS; Department of Structural and Molecular Biology, Division of Biosciences, London, United Kingdom., McCarthy S; Department of Chemistry, Faculty of Mathematical and Physical Sciences, London, United Kingdom., Tabor AB; Department of Chemistry, Faculty of Mathematical and Physical Sciences, London, United Kingdom., Heller GT; Department of Structural and Molecular Biology, Division of Biosciences, London, United Kingdom., Lorenz CD; Department of Engineering, Faculty of Natural, Mathematical and Engineering Sciences, King's College London, London, United Kingdom. Electronic address: chris.lorenz@kcl.ac.uk., Hansen DF; Department of Structural and Molecular Biology, Division of Biosciences, London, United Kingdom; The Francis Crick Institute, London, United Kingdom. Electronic address: d.hansen@ucl.ac.uk.
Publikováno v:
Biophysical journal [Biophys J] 2024 Sep 27. Date of Electronic Publication: 2024 Sep 27.
Autor:
Matwani K; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London, WC1E 6BT, UK., Cornish J; The Francis Crick Institute, London, NW1 1AT, UK., DeBenedictis EA; The Francis Crick Institute, London, NW1 1AT, UK., Heller GT; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London, WC1E 6BT, UK. g.heller@ucl.ac.uk.
Publikováno v:
Journal of biomolecular NMR [J Biomol NMR] 2024 Sep; Vol. 78 (3), pp. 161-167. Date of Electronic Publication: 2024 Jul 27.
Picosecond Dynamics of a Small Molecule in Its Bound State with an Intrinsically Disordered Protein.
Autor:
Heller GT; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, U.K., Shukla VK; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, U.K., Figueiredo AM; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, U.K., Hansen DF; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, U.K.
Publikováno v:
Journal of the American Chemical Society [J Am Chem Soc] 2024 Jan 31; Vol. 146 (4), pp. 2319-2324. Date of Electronic Publication: 2024 Jan 22.
Autor:
Shukla VK; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, UK., Heller GT; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, UK. Electronic address: g.heller@ucl.ac.uk., Hansen DF; Department of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6BT, UK. Electronic address: d.hansen@ucl.ac.uk.
Publikováno v:
Structure (London, England : 1993) [Structure] 2023 Nov 02; Vol. 31 (11), pp. 1360-1374. Date of Electronic Publication: 2023 Oct 16.
Autor:
Löhr T; Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK., Kohlhoff K; Google Research, Mountain View, California 94043, United States., Heller GT; Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK.; Department of Structural and Molecular Biology, University College London, WC1E 6BT London, UK., Camilloni C; Dipartimento di Bioscienze, Università degli Studi di Milano, 20133 Milano, Italy., Vendruscolo M; Department of Chemistry, University of Cambridge, CB2 1EW Cambridge, UK.
Publikováno v:
ACS chemical neuroscience [ACS Chem Neurosci] 2022 Jun 15; Vol. 13 (12), pp. 1738-1745. Date of Electronic Publication: 2022 Jun 01.
Autor:
Löhr T; Department of Chemistry, University of Cambridge, Cambridge, UK., Kohlhoff K; Google Research, Mountain View, CA, USA., Heller GT; Department of Chemistry, University of Cambridge, Cambridge, UK., Camilloni C; Dipartimento di Bioscienze, Università degli Studi di Milano, Milano, Italy., Vendruscolo M; Department of Chemistry, University of Cambridge, Cambridge, UK. mv245@cam.ac.uk.
Publikováno v:
Nature computational science [Nat Comput Sci] 2021 Jan; Vol. 1 (1), pp. 71-78. Date of Electronic Publication: 2021 Jan 14.
Autor:
Heller GT; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK., Aprile FA; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, UK., Michaels TCT; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.; Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA., Limbocker R; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK., Perni M; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK., Ruggeri FS; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK., Mannini B; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK., Löhr T; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK., Bonomi M; Structural Bioinformatics Unit, Department of Structural Biology and Chemistry. CNRS UMR 3528, C3BI, CNRS USR 3756, Institut Pasteur, Paris, France., Camilloni C; Dipartimento di Bioscienze, Università degli Studi di Milano, 20133 Milano, Italy., De Simone A; Division of Molecular Biosciences, Imperial College London, London SW7 2AZ, UK.; Department of Pharmacy, University of Naples 'Federico II,' 80131 Naples, Italy., Felli IC; Magnetic Resonance Center (CERM), University of Florence, 50019 Sesto Fiorentino, Italy.; Department of Chemistry 'Ugo Schiff,' University of Florence, 50019 Sesto Fiorentino, Italy., Pierattelli R; Magnetic Resonance Center (CERM), University of Florence, 50019 Sesto Fiorentino, Italy.; Department of Chemistry 'Ugo Schiff,' University of Florence, 50019 Sesto Fiorentino, Italy., Knowles TPJ; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK., Dobson CM; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK., Vendruscolo M; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK. mv245@cam.ac.uk.
Publikováno v:
Science advances [Sci Adv] 2020 Nov 04; Vol. 6 (45). Date of Electronic Publication: 2020 Nov 04 (Print Publication: 2020).
Autor:
Michaels TCT; Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom.; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138., Šarić A; Department of Physics and Astronomy, Institute for the Physics of Living Systems, University College London, London WC1E 6BT, United Kingdom., Meisl G; Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom., Heller GT; Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom., Curk S; Department of Physics and Astronomy, Institute for the Physics of Living Systems, University College London, London WC1E 6BT, United Kingdom., Arosio P; Department of Chemistry and Applied Biosciences, ETH Zürich, 8093 Zürich, Switzerland., Linse S; Department of Chemistry, Division for Biochemistry and Structural Biology, Lund University, 221 00 Lund, Sweden., Dobson CM; Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom., Vendruscolo M; Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom; mv245@cam.ac.uk tpjk2@cam.ac.uk., Knowles TPJ; Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, United Kingdom; mv245@cam.ac.uk tpjk2@cam.ac.uk.; Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge, CB3 0HE, United Kingdom.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 29; Vol. 117 (39), pp. 24251-24257. Date of Electronic Publication: 2020 Sep 14.