Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Hellen Hiza"'
Autor:
Hellen Hiza, Michaela Zwyer, Jerry Hella, Ainhoa Arbués, Mohamed Sasamalo, Sonia Borrell, Zhi Ming Xu, Amanda Ross, Daniela Brites, Jacques Fellay, Klaus Reither, Sébastien Gagneux, Damien Portevin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The Mycobacterium tuberculosis complex (MTBC) comprises nine human-adapted lineages that differ in their geographical distribution. Local adaptation of specific MTBC genotypes to the respective human host population has been invoked in this
Externí odkaz:
https://doaj.org/article/8b12710901d645ebb56de03bec491002
Autor:
Yves Tschan, Mohamed Sasamalo, Hellen Hiza, Jacques Fellay, Sébastien Gagneux, Klaus Reither, Jerry Hella, Damien Portevin
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) remains one of the deadliest infectious diseases globally. Timely diagnosis is a key step in the management of TB patients and in the prevention of further transmission events. Cur
Externí odkaz:
https://doaj.org/article/ed83b4e23b884940a7101b59ee91b77a
Autor:
Michaela Zwyer, Liliana K Rutaihwa, Etthel Windels, Jerry Hella, Fabrizio Menardo, Mohamed Sasamalo, Gregor Sommer, Lena Schmülling, Sonia Borrell, Miriam Reinhard, Anna Dötsch, Hellen Hiza, Christoph Stritt, George Sikalengo, Lukas Fenner, Bouke C De Jong, Midori Kato-Maeda, Levan Jugheli, Joel D Ernst, Stefan Niemann, Leila Jeljeli, Marie Ballif, Matthias Egger, Niaina Rakotosamimanana, Dorothy Yeboah-Manu, Prince Asare, Bijaya Malla, Horng Yunn Dou, Nicolas Zetola, Robert J Wilkinson, Helen Cox, E Jane Carter, Joachim Gnokoro, Marcel Yotebieng, Eduardo Gotuzzo, Alash'le Abimiku, Anchalee Avihingsanon, Zhi Ming Xu, Jacques Fellay, Damien Portevin, Klaus Reither, Tanja Stadler, Sebastien Gagneux, Daniela Brites
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1010893 (2023)
In settings with high tuberculosis (TB) endemicity, distinct genotypes of the Mycobacterium tuberculosis complex (MTBC) often differ in prevalence. However, the factors leading to these differences remain poorly understood. Here we studied the MTBC p
Externí odkaz:
https://doaj.org/article/ba4d547f4bca4dfbb5d867e96b99308e
Autor:
Hellen Hiza, Jerry Hella, Ainhoa Arbués, Beatrice Magani, Mohamed Sasamalo, Sebastien Gagneux, Klaus Reither, Damien Portevin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract CD4 T cell phenotyping-based blood assays have the potential to meet WHO target product profiles (TPP) of non-sputum-biomarker-based tests to diagnose tuberculosis (TB). Yet, substantial refinements are required to allow their implementation
Externí odkaz:
https://doaj.org/article/04efe1c3328540c29aa3a11fea40f034
Autor:
Hellen Hiza, Jerry Hella, Ainhoa Arbués, Mohamed Sasamalo, Veronica Misana, Jacques Fellay, Sébastien Gagneux, Klaus Reither, Damien Portevin
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
T cell activation markers (TAM) expressed by antigen-specific T cells constitute promising candidates to attest the presence of an active infection by Mycobacterium tuberculosis (Mtb). Reciprocally, their modulation may be used to assess antibiotic t
Externí odkaz:
https://doaj.org/article/29c22cb010bb4c4a9ef4bd8f4e67f9cd
Autor:
Zhi Ming Xu, Sina Rüeger, Michaela Zwyer, Daniela Brites, Hellen Hiza, Miriam Reinhard, Liliana Rutaihwa, Sonia Borrell, Faima Isihaka, Hosiana Temba, Thomas Maroa, Rastard Naftari, Jerry Hella, Mohamed Sasamalo, Klaus Reither, Damien Portevin, Sebastien Gagneux, Jacques Fellay
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 1, p e1009628 (2022)
Genome-wide association studies rely on the statistical inference of untyped variants, called imputation, to increase the coverage of genotyping arrays. However, the results are often suboptimal in populations underrepresented in existing reference p
Externí odkaz:
https://doaj.org/article/8e617648b5514944a890955364868275
Autor:
Monica R. Ticlla, Jerry Hella, Hellen Hiza, Mohamed Sasamalo, Francis Mhimbira, Liliana K. Rutaihwa, Sara Droz, Sarah Schaller, Klaus Reither, Markus Hilty, Inaki Comas, Christian Beisel, Christoph D. Schmid, Lukas Fenner, Sebastien Gagneux
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Each day, approximately 27,000 people become ill with tuberculosis (TB), and 4,000 die from this disease. Pulmonary TB is the main clinical form of TB, and affects the lungs with a considerably heterogeneous manifestation among patients. Immunomodula
Externí odkaz:
https://doaj.org/article/ec7167d45e2a4ea1b99fd86b2ac09c1f
Autor:
Fabrizio Menardo, Liliana K. Rutaihwa, Michaela Zwyer, Sonia Borrell, Iñaki Comas, Emilyn Costa Conceição, Mireia Coscolla, Helen Cox, Moses Joloba, Horng-Yunn Dou, Julia Feldmann, Lukas Fenner, Janet Fyfe, Qian Gao, Darío García de Viedma, Alberto L. Garcia-Basteiro, Sebastian M. Gygli, Jerry Hella, Hellen Hiza, Levan Jugheli, Lujeko Kamwela, Midori Kato-Maeda, Qingyun Liu, Serej D. Ley, Chloe Loiseau, Surakameth Mahasirimongkol, Bijaya Malla, Prasit Palittapongarnpim, Niaina Rakotosamimanana, Voahangy Rasolofo, Miriam Reinhard, Klaus Reither, Mohamed Sasamalo, Rafael Silva Duarte, Christophe Sola, Philip Suffys, Karla Valeria Batista Lima, Dorothy Yeboah-Manu, Christian Beisel, Daniela Brites, Sebastien Gagneux
Publikováno v:
F1000Research, Vol 10 (2021)
Background: Lineage 1 (L1) and 3 (L3) are two lineages of the Mycobacterium tuberculosis complex (MTBC) causing tuberculosis (TB) in humans. L1 and L3 are prevalent around the rim of the Indian Ocean, the region that accounts for most of the world’
Externí odkaz:
https://doaj.org/article/aad2fd7b8e904efa971f77b2e792f962
Autor:
Fabrizio Menardo, Liliana K. Rutaihwa, Michaela Zwyer, Sonia Borrell, Iñaki Comas, Emilyn Costa Conceição, Mireia Coscolla, Helen Cox, Moses Joloba, Horng-Yunn Dou, Julia Feldmann, Lukas Fenner, Janet Fyfe, Qian Gao, Darío García de Viedma, Alberto L. Garcia-Basteiro, Sebastian M. Gygli, Jerry Hella, Hellen Hiza, Levan Jugheli, Lujeko Kamwela, Midori Kato-Maeda, Qingyun Liu, Serej D. Ley, Chloe Loiseau, Surakameth Mahasirimongkol, Bijaya Malla, Prasit Palittapongarnpim, Niaina Rakotosamimanana, Voahangy Rasolofo, Miriam Reinhard, Klaus Reither, Mohamed Sasamalo, Rafael Silva Duarte, Christophe Sola, Philip Suffys, Karla Valeria Batista Lima, Dorothy Yeboah-Manu, Christian Beisel, Daniela Brites, Sebastien Gagneux
Publikováno v:
F1000Research, Vol 10 (2021)
Background: Lineage 1 (L1) and 3 (L3) are two lineages of the Mycobacterium tuberculosis complex (MTBC) causing tuberculosis (TB) in humans. L1 and L3 are prevalent around the rim of the Indian Ocean, the region that accounts for most of the world’
Externí odkaz:
https://doaj.org/article/4d5dfdfc4781497ab344ec1aa3eac2c4
Autor:
Hellen Hiza, Basra Doulla, Mohamed Sasamalo, Jerry Hella, Lujeko Kamwela, Francis Mhimbira, Klaus Reither, Sebastien Gagneux, Levan Jugheli, Lukas Fenner
Publikováno v:
BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-6 (2017)
Abstract Background Culture contamination with environmental bacteria is a major challenge in tuberculosis (TB) laboratories in hot and humid climate zones. We studied the effect of cetylpyridinium chloride (CPC) preservation on culture results and p
Externí odkaz:
https://doaj.org/article/6b23ec9623de438cac83b907d4500c27