A microsporidian impairs Plasmodium falciparum transmission in Anopheles arabiensis mosquitoes

Autor: Jeremy K. Herren, Lilian Mbaisi, Enock Mararo, Edward E. Makhulu, Victor A. Mobegi, Hellen Butungi, Maria Vittoria Mancini, Joseph W. Oundo, Evan T. Teal, Silvain Pinaud, Mara K. N. Lawniczak, Jordan Jabara, Godfrey Nattoh, Steven P. Sinkins

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)

Mircobial symbionts of mosquitoes can affect transmission of human pathogens. Here, Herren et al. identify a microsporidian symbiont in Anopheles gambiae that impairs transmission without affecting mosquito fecundity or survival.

Externí odkaz: https://doaj.org/article/0fa0d0f941944f2ca631820247f5217a

The fungus Leptosphaerulina persists in Anopheles gambiae and induces melanization.

Autor: Godfrey Nattoh, Joel L Bargul, Gabriel Magoma, Lilian Mbaisi, Hellen Butungi, Enock Mararo, Evan Teal, Jeremy Keith Herren

Publikováno v: PLoS ONE, Vol 16, Iss 2, p e0246452 (2021)

Anopheles mosquitoes are colonized by diverse microorganisms that may impact on host biology and vectorial capacity. Eukaryotic symbionts such as fungi have been isolated from Anopheles, but whether they are stably associated with mosquitoes and tran

Externí odkaz: https://doaj.org/article/3636b143495d4ce09ae29bd778cd8725

A microsporidian impairs Plasmodium falciparum transmission in Anopheles arabiensis mosquitoes

Autor: Edward Edmond Makhulu, Mara K. N. Lawniczak, Maria Vittoria Mancini, Lilian Mbaisi, Joseph Wang’ang’a Oundo, Silvain Pinaud, Victor A. Mobegi, Jeremy K. Herren, Hellen Butungi, Steven P. Sinkins, Enock Mararo, Jordan Jabara, Evan Teal, Godfrey Nattoh

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Herren, J K, Mbaisi, L, Mararo, E, Makhulu, E E, Mobegi, V A, Butungi, H, Mancini, M V, Oundo, J W, Teal, E T, Pinaud, S, Lawniczak, M K N, Jabara, J, Nattoh, G & Sinkins, S P 2020, ' A microsporidian impairs Plasmodium falciparum transmission in Anopheles arabiensis mosquitoes ', Nature Communications, vol. 11, no. 1, 2187, pp. 1-10 . https://doi.org/10.1038/s41467-020-16121-y
Nature Communications

A possible malaria control approach involves the dissemination in mosquitoes of inherited symbiotic microbes to block Plasmodium transmission. However, in the Anopheles gambiae complex, the primary African vectors of malaria, there are limited report

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52cf5c3ed1c2f3776533b846986dcb6
http://link.springer.com/article/10.1038/s41467-020-16121-y

Prevalence of asymptomatic

Autor: Abdoulie O, Touray, Victor A, Mobegi, Fred, Wamunyokoli, Hellen, Butungi, Jeremy K, Herren

Publikováno v: Wellcome Open Research

Background: Asymptomatic Plasmodium falciparum gametocyte carriers are reservoirs for sustaining transmission in malaria endemic regions. Gametocyte presence in the host peripheral blood is a predictor of capacity to transmit malaria. However, it doe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b2151065f0e4bf30e09a2a97c4c69e43
https://pubmed.ncbi.nlm.nih.gov/33959684

A Microsporidian blocksPlasmodium falciparumtransmission inAnopheles arabiensismosquitoes

Autor: Maria Vittoria Mancini, Steven P. Sinkins, Lilian Mbaisi, Hellen Butungi, Edward Edmond Makhulu, Jeremy K. Herren, Jordan Jabara, Joseph Wang’ang’a Oundo, Enock Mararo, Victor A. Mobegi

Malaria imposes an enormous burden on sub-Saharan Africa, and evidence that incidence could be starting to increase again1suggests the limits of currently applied control strategies have now been reached. A possible novel control approach involves th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bac26f30d040d8f45dd07d65b48aa5a