Zobrazeno 1 - 10 of 388 pro vyhledávání: '"Helleberg H"'
1
Akademický článek
Enhanced disulphide bond stability contributes to the once-weekly profile of insulin icodec.
Autor: Hubálek F; Novo Nordisk A/S, Maaloev, Denmark. FHUB@novonordisk.com., Cramer CN; Novo Nordisk A/S, Maaloev, Denmark., Helleberg H; Novo Nordisk A/S, Maaloev, Denmark., Johansson E; Novo Nordisk A/S, Maaloev, Denmark., Nishimura E; Novo Nordisk A/S, Maaloev, Denmark., Schluckebier G; Novo Nordisk A/S, Maaloev, Denmark., Steensgaard DB; Novo Nordisk A/S, Maaloev, Denmark., Sturis J; Novo Nordisk A/S, Maaloev, Denmark., Kjeldsen TB; Novo Nordisk A/S, Maaloev, Denmark.
Publikováno v: Nature communications [Nat Commun] 2024 Jul 20; Vol. 15 (1), pp. 6124. Date of Electronic Publication: 2024 Jul 20.
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2
Akademický článek
Comparison of the Tissue Distribution of a Long-Circulating Glucagon-like Peptide-1 Agonist Determined by Positron Emission Tomography and Quantitative Whole-Body Autoradiography.
Autor: Fernandes EFA; Global Drug Discovery, Novo Nordisk A/S, Novo Nordisk Park 1, DK-2760 Måløv, Denmark., Wilbs J; Global Research Technologies, Novo Nordisk A/S, Novo Nordisk Park 1, DK-2760 Måløv, Denmark., Raavé R; Radboudumc, Department of Medical Imaging - Nuclear Medicine, Radboud Institute for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands., Jacobsen CB; Isotope Chemistry, CMC Development, Novo Nordisk A/S, Novo Nordisk Park 1, DK-2760 Måløv, Denmark., Toftelund H; Global Drug Discovery, Novo Nordisk A/S, Novo Nordisk Park 1, DK-2760 Måløv, Denmark., Helleberg H; Global Drug Discovery, Novo Nordisk A/S, Novo Nordisk Park 1, DK-2760 Måløv, Denmark., Boswinkel M; Radboudumc, Department of Medical Imaging - Nuclear Medicine, Radboud Institute for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands., Heskamp S; Radboudumc, Department of Medical Imaging - Nuclear Medicine, Radboud Institute for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands., Gustafsson MBF; Global Research Technologies, Novo Nordisk A/S, Novo Nordisk Park 1, DK-2760 Måløv, Denmark., Bjørnsdottir I; Global Drug Discovery, Novo Nordisk A/S, Novo Nordisk Park 1, DK-2760 Måløv, Denmark.
Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2022 Jun 30; Vol. 5 (8), pp. 616-624. Date of Electronic Publication: 2022 Jun 30 (Print Publication: 2022).
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3
Akademický článek
Protein adducts: quantitative and qualitative aspects of their formation, analysis and applications
Autor: Törnqvist, M. ∗, Fred, C., Haglund, J., Helleberg, H., Paulsson, B., Rydberg, P.
Publikováno v: In Journal of Chromatography B 2002 778(1):279-308
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4
Akademický článek
Structure identification of circulating metabolites from somapacitan, a long-acting growth hormone derivative, and pharmacokinetics after single and multiple subcutaneous dosing in rats.
Autor: Helleberg H; Global Discovery & Development Sciences, Novo Nordisk A/S, Måløv, Denmark. Electronic address: hhll@novonordisk.com., Lindecrona RH; Global Discovery & Development Sciences, Novo Nordisk A/S, Måløv, Denmark., Thygesen P; Global Discovery & Development Sciences, Novo Nordisk A/S, Måløv, Denmark., Bjelke M; Global Discovery & Development Sciences, Novo Nordisk A/S, Måløv, Denmark.
Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2022 Jan 01; Vol. 168, pp. 106032. Date of Electronic Publication: 2021 Oct 02.
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5
Akademický článek
Absorption, metabolism and excretion of once-weekly somapacitan, a long-acting growth hormone derivative, after single subcutaneous dosing in human subjects.
Autor: Helleberg H; Global Discovery and Development Sciences, Novo Nordisk A/S, Måløv, Denmark. Electronic address: hhll@novonordisk.com., Bjelke M; Global Discovery and Development Sciences, Novo Nordisk A/S, Måløv, Denmark. Electronic address: msbp@novonordisk.com., Damholt BB; Stem Cell Development, Novo Nordisk A/S, Måløv, Denmark., Pedersen PJ; Isotope Chemistry, Novo Nordisk A/S, Bagsværd, Denmark. Electronic address: pjcp@novonordisk.com., Rasmussen MH; Stem Cell Development, Novo Nordisk A/S, Måløv, Denmark; Clinical Drug Development, Novo Nordisk A/S, Søborg, Denmark. Electronic address: mhr@novonordisk.com.
Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2021 Dec 01; Vol. 167, pp. 106030. Date of Electronic Publication: 2021 Oct 01.
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6
Akademický článek
A new group housing approach for non-human primate metabolism studies.
Autor: Stow R; Covance Laboratories Ltd., Harrogate, UK. Electronic address: ruth.stow@covance.com., Kendrick J; Covance Laboratories Ltd., Harrogate, UK. Electronic address: john.kendrick@covance.com., Ibbotson N; Covance Laboratories Ltd., Harrogate, UK. Electronic address: neil.ibbotson@covance.com., Adjin-Tettey G; Covance Laboratories Ltd., Harrogate, UK. Electronic address: georgina.adjin-tettey@covance.com., Murphy B; Covance Laboratories Ltd., Harrogate, UK. Electronic address: beverley.murphy@covance.com., Trojca R; Covance Laboratories Ltd., Harrogate, UK. Electronic address: richard.trojca@covance.com., Miller J; Covance Laboratories Ltd., Harrogate, UK. Electronic address: james.miller@covance.com., Konradsen G; Novo Nordisk A/S, Novo Nordisk Park, Denmark. Electronic address: saq@novonordisk.com., Øvlisen K; Novo Nordisk A/S, Novo Nordisk Park, Denmark. Electronic address: mefg@novonordisk.com., Helleberg H; Novo Nordisk A/S, Novo Nordisk Park, Denmark. Electronic address: hhll@novonordisk.com., Hansen JJ; Novo Nordisk A/S, Novo Nordisk Park, Denmark. Electronic address: jrjh@novonordisk.com.
Publikováno v: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2021 Jan-Feb; Vol. 107, pp. 106947. Date of Electronic Publication: 2021 Jan 09.
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7
Akademický článek
A novel welfare and scientific approach to conducting dog metabolism studies allowing dogs to be pair housed.
Autor: Kendrick J; Covance Laboratories Ltd, North Yorkshire, UK., Stow R; Covance Laboratories Ltd, North Yorkshire, UK., Ibbotson N; Covance Laboratories Ltd, North Yorkshire, UK., Adjin-Tettey G; Covance Laboratories Ltd, North Yorkshire, UK., Murphy B; Covance Laboratories Ltd, North Yorkshire, UK., Bailey G; Covance Laboratories Ltd, North Yorkshire, UK., Miller J; Covance Laboratories Ltd, North Yorkshire, UK., Helleberg H; Novo Nordisk A/S, Måløv, Denmark., Finderup Grove M; Novo Nordisk A/S, Måløv, Denmark., Øvlisen K; Novo Nordisk A/S, Måløv, Denmark., Hansen JJ; Novo Nordisk A/S, Måløv, Denmark.
Publikováno v: Laboratory animals [Lab Anim] 2020 Dec; Vol. 54 (6), pp. 588-598. Date of Electronic Publication: 2020 Feb 16.
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9
Akademický článek
Analytical methods based on liquid chromatography for the analysis of albumin adducts involved in retrospective biomonitoring of exposure to mustard agents.
Autor: Avigo, Lorenzo1,2 (AUTHOR), Hallez, Florine1 (AUTHOR), Combès, Audrey1 (AUTHOR), Desoubries, Charlotte3 (AUTHOR), Albaret, Christine3 (AUTHOR), Bossée, Anne3 (AUTHOR), Pichon, Valérie1,2 (AUTHOR) valerie.pichon@espci.fr
Publikováno v: Analytical & Bioanalytical Chemistry. Apr2024, Vol. 416 Issue 9, p2173-2188. 16p.
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10
Akademický článek
Bioluminescence imaging of Cyp1a1-luciferase reporter mice demonstrates prolonged activation of the aryl hydrocarbon receptor in the lung.
Autor: Veland, Nicolas1 (AUTHOR), Gleneadie, Hannah J.1 (AUTHOR), Brown, Karen E.1 (AUTHOR), Sardini, Alessandro2 (AUTHOR), Pombo, Joaquim3 (AUTHOR), Dimond, Andrew1,4 (AUTHOR), Burns, Vanessa1 (AUTHOR), Sarkisyan, Karen5 (AUTHOR), Schiering, Chris6 (AUTHOR), Webster, Zoe7 (AUTHOR), Merkenschlager, Matthias8 (AUTHOR), Fisher, Amanda G.1,4 (AUTHOR) amanda.fisher@bioch.ox.ac.uk
Publikováno v: Communications Biology. 4/10/2024, Vol. 7 Issue 1, p1-13. 13p.
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