Výsledky vyhledávání - "Helle K Johansen"

Akademický článek

Effect of long-term voluntary exercise wheel running on susceptibility to bacterial pulmonary infections in a mouse model.

Autor: Pauline B van de Weert-van Leeuwen, Angélica M M de Vrankrijker, Joachim Fentz, Oana Ciofu, Jørgen F P Wojtaszewski, Hubertus G M Arets, Hendrikus J Hulzebos, Cornelis K van der Ent, Jeffrey M Beekman, Helle K Johansen

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82869 (2013)

Regular moderate exercise has been suggested to exert anti-inflammatory effects and improve immune effector functions, resulting in reduced disease incidence and viral infection susceptibility. Whether regular exercise also affects bacterial infectio

Externí odkaz: https://doaj.org/article/084af9483f9647a793a589e1a43a9c64

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Akademický článek

Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams

Autor: Claudia A. Colque, Andrea G. albarracín Orio, Pablo E. Tomatis, Gina Dotta, Diego M. Moreno, Laura G. Hedemann, Rachel A. Hickman, Lea M. Sommer, Sofía Feliziani, Alejandro J. Moyano, Robert A. Bonomo, Helle K. Johansen, Søren Molin, Alejandro J. Vila, Andrea M. Smania

Publikováno v: mBio, Vol 13, Iss 5 (2022)

ABSTRACT Traditional studies on the evolution of antibiotic resistance development use approaches that can range from laboratory-based experimental studies, to epidemiological surveillance, to sequencing of clinical isolates. However, evolutionary tr

Externí odkaz: https://doaj.org/article/70924af419ec406b88dabded5e47d448

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Akademický článek

Gene Loss and Acquisition in Lineages of Pseudomonas aeruginosa Evolving in Cystic Fibrosis Patient Airways

Autor: Migle Gabrielaite, Helle K. Johansen, Søren Molin, Finn C. Nielsen, Rasmus L. Marvig

Publikováno v: mBio, Vol 11, Iss 5 (2020)

ABSTRACT Genome analyses have documented that there are differences in gene repertoire between evolutionary distant lineages of the same bacterial species; however, less is known about microevolutionary dynamics of gene loss and acquisition within ba

Externí odkaz: https://doaj.org/article/84197cb71d2e4dbe9d2b7c9247d203e5

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Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease

Publikováno v: Eklöf, J, Misiakou, M A, Sivapalan, P, Armbruster, K, Browatzki, A, Nielsen, T L, Lapperre, T S, Andreassen, H F, Janner, J, Ulrik, C S, Gabrielaite, M, Johansen, H K, Jensen, A, Nielsen, T V, Hertz, F B, Ghathian, K, Calum, H, Wilcke, T, Seersholm, N, Jensen, J U S & Marvig, R L 2022, ' Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease ', Clinical Microbiology and Infection, vol. 28, no. 7, pp. 990-995 . https://doi.org/10.1016/j.cmi.2022.01.017

Objectives: It is unclear whether recurrent sputum culture with Pseudomonas aeruginosa from patients with chronic obstructive pulmonary disease (COPD) is caused by intermittent airway carriage by different P. aeruginosa lineages or persistent carriag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afe1ef377c6cb2ede85866c97993d68
https://doi.org/10.1016/j.cmi.2022.01.017

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Transmission and Antibiotic Resistance of

Autor: Migle, Gabrielaite, Jennifer A, Bartell, Niels, Nørskov-Lauritsen, Tacjana, Pressler, Finn C, Nielsen, Helle K, Johansen, Rasmus L, Marvig

Publikováno v: Journal of Clinical Microbiology

Achromobacter species are increasingly being detected in patients with cystic fibrosis (CF), and this emerging pathogen is associated with antibiotic resistance and more-severe disease outcomes. Nonetheless, little is known about the extent of transm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::061b40ab9b2d911d5f4a4aefae4fae84
https://pubmed.ncbi.nlm.nih.gov/33472899

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Transmission and antibiotic resistance ofAchromobacterin cystic fibrosis

Autor: Migle Gabrielaite, Jennifer A. Bartell, Niels Nørskov-Lauritsen, Tacjana Pressler, Finn C. Nielsen, Helle K. Johansen, Rasmus L. Marvig

Achromobacterspecies are increasingly being detected in patients with cystic fibrosis (CF), and this emerging pathogen is associated with antibiotic resistance and more severe disease outcomes. Nonetheless, little is known about the extent of transmi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f69a038dc582a92c55b82afddb6b04ff
https://doi.org/10.1101/2020.08.04.235952

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Antibiotic resistance in

Autor: Lea M, Sommer, Helle K, Johansen, Søren, Molin

Publikováno v: Microbial Genomics

Antibiotic resistance has become a serious threat to human health (WHO Antibacterial Agents in Clinical Development: an Analysis of the Antibacterial Clinical Development Pipeline, Including Tuberculosis. Geneva: World Health Organization; 2017), and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3201798636ee39dafad09bb7ec76e818
https://pubmed.ncbi.nlm.nih.gov/32375975

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Primary ciliary dyskinesia patients have the same

Autor: Elisabeth, Arndal, Helle K, Johansen, Janus A J, Haagensen, Jennifer A, Bartell, Rasmus L, Marvig, Mikkel, Alanin, Kasper, Aanæs, Niels, Høiby, Kim G, Nielsen, Vibeke, Backer, Christian, von Buchwald

Publikováno v: The European respiratory journal. 55(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3af3c9e89855c8db9b823ff625a065dc
https://pubmed.ncbi.nlm.nih.gov/31558658

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The Small RNA ErsA of Pseudomonas aeruginosa Contributes to Biofilm Development and Motility through Post-transcriptional Modulation of AmrZ

Autor: Marilena Falcone, Silvia Ferrara, Elio Rossi, Helle K. Johansen, Søren Molin, Giovanni Bertoni

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)

The small RNA ErsA of Pseudomonas aeruginosa was previously suggested to be involved in biofilm formation via negative post-transcriptional regulation of the algC gene that encodes the virulence-associated enzyme AlgC, which provides sugar precursors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::56f8095fc4e7ceb82dae90d433b29529
http://journal.frontiersin.org/article/10.3389/fmicb.2018.00238/full

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Akademický článek

Diversity, Prevalence, and Longitudinal Occurrence of Type II Toxin-Antitoxin Systems of Pseudomonas aeruginosa Infecting Cystic Fibrosis Lungs

Autor: Sandra B. Andersen, Melanie Ghoul, Ashleigh S. Griffin, Bent Petersen, Helle K. Johansen, Søren Molin

Publikováno v: Frontiers in Microbiology, Vol 8 (2017)

Type II toxin-antitoxin (TA) systems are most commonly composed of two genes encoding a stable toxin, which harms the cell, and an unstable antitoxin that can inactivate it. TA systems were initially characterized as selfish elements, but have recent

Externí odkaz: https://doaj.org/article/2977ecacb7db43668c181be36c325f85

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