Organization and biology of the porcine serum amyloid A (SAA) gene cluster: isoform specific responses to bacterial infection.

Autor: Helle G Olsen, Kerstin Skovgaard, Ole L Nielsen, Páll S Leifsson, Henrik E Jensen, Tine Iburg, Peter M H Heegaard

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e76695 (2013)

Serum amyloid A (SAA) is a prominent acute phase protein. Although its biological functions are debated, the wide species distribution of highly homologous SAA proteins and their uniform behavior in response to injury or inflammation in itself sugges

Externí odkaz: https://doaj.org/article/fd2918055dbc445891c6c56816d7fd60

The impact of Staphylococcus aureus concentration on the development of pulmonary lesions and cytokine expression after intravenous inoculation of pigs

Autor: Bent Aalbæk, Ole L. Nielsen, Kerstin Skovgaard, Peter M. H. Heegaard, Bo Wiinberg, Tine Iburg, Annemarie T. Kristensen, Helle G Olsen, Mads Kjelgaard-Hansen, Henrik Jeldtoft Jensen, Pall S. Leifsson, K. E. Soerensen

Publikováno v: Sørensen, K E, Skovgaard, K, Heegaard, P M H, Jensen, H E, Nielsen, O L, Leifsson, P S, Olsen, H G, Aalbæk, B, Kristensen, A T, Kjelgaard-Hansen, M, Wiinberg, B & Iburg, T M 2012, ' The impact of Staphylococcus aureus concentration on the development of pulmonary lesions and cytokine expression after intravenous inoculation of pigs ', Veterinary Pathology, vol. 49, no. 6, pp. 950-962 . https://doi.org/10.1177/0300985812439726

Acute respiratory distress syndrome is a common complication in severe sepsis. In pigs, the lungs play an important role in clearing systemic bacterial infections due to pulmonary intravascular macrophages found specifically in pigs. However, this in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9baa3f13e06fcbd956526bb8751e853d
https://curis.ku.dk/ws/files/44175921/Veterinary_Pathology_2012_Soerensen_1.pdf

Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified?

Autor: Pall S. Leifsson, Tine Iburg, Pernille Tveden-Nyborg, Malene M. Birck, Bent Aalbæk, Peter M. H. Heegaard, Karsten Pharao Hammelev, Helle G Olsen, Ole L. Nielsen, Mads Kjelgaard-Hansen, Andreas Vegge, Henrik Jeldtoft Jensen

Publikováno v: Olsen, H G, Kjeldgaard-Hansen, M, Tveden-Nyborg, P, Birck, M M, Hammelev, K P, Vegge, A, Aalbæk, B, Leifsson, P S, Jensen, H E, Iburg, T, Heegaard, P M H & Nielsen, O L 2016, ' Modelling severe Staphylococcus aureus sepsis in conscious pigs : are implications for animal welfare justified? ', BMC Research Notes, vol. 9, 99, pp. 1-10 . https://doi.org/10.1186/s13104-016-1888-7
Olsen, H G, Kjelgaard-Hansen, M, Tveden-Nyborg, P, Birck, M M, Hammelev, K P, Vegge, A, Aalbæk, B, Leifsson, P S, Jensen, H E, Moesgaard Iburg, T, Heegaard, P M H & Nielsen, O L 2016, ' Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified? ', BMC Research Notes, vol. 9, no. 1, 99 . https://doi.org/10.1186/s13104-016-1888-7
BMC Research Notes

Background A porcine model of haematogenous Staphylococcus aureus sepsis has previously been established in our research group. In these studies, pigs developed severe sepsis including liver dysfunction during a 48 h study period. As pigs were awake

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6e9a3d984463390ac04630b7eb9a8f