Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Helle Kristiansen"'
Publikováno v:
Kristiansen, H, Gad, H H, Larsen, S E, Despres, P & Hartmann, R 2011, ' The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities ', Journal of Interferon & Cytokine Research, vol. 31, no. 1, pp. 41-47 . https://doi.org/10.1089/jir.2010.0107
The 2'-5' oligoadenylate synthetases (OAS) are interferon-induced antiviral enzymes that recognize virally produced dsRNA and initiate RNA destabilization through activation of RNase L within infected cells. However, recent evidence points toward sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935fac1e9430a4e934375d05a141730a
https://doi.org/10.1089/jir.2010.0107
https://doi.org/10.1089/jir.2010.0107
Autor:
Thomas Kuri, Helle Kristiansen, Maralee Mcvean, Shawn P. Iadonato, Rune Hartmann, Friedemann Weber, Christina A. Scherer, Susanne Vends, Kristy A. Horan, Karthiga Thavachelvam, Thomas B. Steffensen, Søren R. Paludan
Publikováno v:
Kristiansen, H, Scherer, C A, McVean, M, Iadonato, S P, Vends, S, Thavachelvam, K, Steffensen, T B, Horan, K A, Kuri, T, Weber, F, Paludan, S R & Hartmann, R 2010, ' Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity ', Journal of Virology, vol. 84, no. 22, pp. 11898-904 . https://doi.org/10.1128/JVI.01003-10
The 2′-5′ oligoadenylate synthetase (OAS) proteins are traditionally considered intracellular antiviral proteins. However, several studies demonstrate a correlation between the concentration of freely circulating OAS protein in sera from hepatiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17db3240cca48a783e885e7786c1cbfc
https://pure.au.dk/portal/da/publications/extracellular-25-oligoadenylate-synthetase-stimulates-rnase-lindependent-antiviral-activity-a-novel-mechanism-of-virusinduced-innate-immunity(5b9d3f0e-2ac6-41b4-96d6-4655c5c02194).html
https://pure.au.dk/portal/da/publications/extracellular-25-oligoadenylate-synthetase-stimulates-rnase-lindependent-antiviral-activity-a-novel-mechanism-of-virusinduced-innate-immunity(5b9d3f0e-2ac6-41b4-96d6-4655c5c02194).html
Autor:
Johanna Rintahaka, Jesper Melchjorsen, Søren R. Paludan, Helle Kristiansen, Sampsa Matikainen, Rune Hartmann, Rune Christiansen
Publikováno v:
Melchjorsen, J, Kristiansen, H, Christiansen, R, Rintahaka, J, Matikainen, S, Paludan, S R & Hartmann, R 2009, ' Differential Regulation of the OASL and OAS1 Genes in Response to Viral Infections ', Journal of Interferon & Cytokine Research . https://doi.org/10.1089/jir.2008.0050
Udgivelsesdato: 2009-Feb-9 The 2'-5' oligoadenylate synthetase (OAS) family consist of three genes encoding active OAS enzymes (OAS1-3) and an OAS-Like (OASL) gene encoding an inactive protein. The transcription of all four members of this family is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7375498a3a4ca1ae8b6e5abf655cd055
https://pure.au.dk/portal/da/publications/differential-regulation-of-the-oasl-and-oas1-genes-in-response-to-viral-infections(c7efe670-fcd3-11dd-a987-000ea68e967b).html
https://pure.au.dk/portal/da/publications/differential-regulation-of-the-oasl-and-oas1-genes-in-response-to-viral-infections(c7efe670-fcd3-11dd-a987-000ea68e967b).html
Publikováno v:
Cytokine. 59:555
Introduction The 2′-5′ Oligoadenylate Synthetase (OAS) family of proteins consist of 4 genes in humans, classical they act via production of 2′-5′ linked Oligoadenylates (2-5A), which activate RNase L and lead to the degradation of cellular a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122f621443fb062888883390c31a353d
https://doi.org/10.1016/j.cyto.2012.06.201
https://doi.org/10.1016/j.cyto.2012.06.201
Publikováno v:
Cytokine. 56:55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2278755f06a77fe222696cc43f9e3442
https://doi.org/10.1016/j.cyto.2011.07.351
https://doi.org/10.1016/j.cyto.2011.07.351
Publikováno v:
Cytokine. 48:89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b27057267e1053638544b80298ded655
https://doi.org/10.1016/j.cyto.2009.07.322
https://doi.org/10.1016/j.cyto.2009.07.322
Autor:
Jesper Melchjorsen, Helle Kristiansen, Rune Christiansen, Johanna Rintahaka, Sampsa Matikainen, Søren R. Paludan, Rune Hartmann
Publikováno v:
Journal of Interferon & Cytokine Research; Apr2009, Vol. 29 Issue 4, p199-208, 10p