Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Hella S. Brönneke"'
Autor:
Johan Ruud, Jens Alber, Anna Tokarska, Linda Engström Ruud, Hendrik Nolte, Nasim Biglari, Rachel Lippert, Änne Lautenschlager, Przemysław E. Cieślak, Łukasz Szumiec, Martin E. Hess, Hella S. Brönneke, Marcus Krüger, Hans Nissbrandt, Tatiana Korotkova, Gilad Silberberg, Jan Rodriguez Parkitna, Jens C. Brüning
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3182-3198.e9 (2019)
Summary: Variations in the human FTO gene have been linked to obesity and altered connectivity of the dopaminergic neurocircuitry. Here, we report that fat mass and obesity-associated protein (FTO) in dopamine D2 receptor-expressing medium spiny neur
Externí odkaz:
https://doaj.org/article/a536d8e99e444152a3de8a1661f87a00
Autor:
Hella S. Brönneke, Randy J. Seeley, Bo-Yeong Jin, Dong Hoon Kim, Hye Jin Lee, Haifei Shi, Sang Hyun Choi
Publikováno v:
Journal of Endocrinology. 251:195-206
Vascular reactivity of adipose tissue (AT) is hypothesized to play an important role in the development of obesity. However, the exact role of vascular reactivity in the development of obesity remains unclear. In this study, we investigated the chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361e04d7faf7946d33aef29a59efa190
https://doi.org/10.1530/joe-21-0187
https://doi.org/10.1530/joe-21-0187
Autor:
Hella S. Brönneke, Jan Mauer, Joel Schmitz, Arne Dietrich, Jens C. Brüning, Motoharu Awazawa, Hayley T. Nicholls, Nadine Evers, Matthias Blüher
Publikováno v:
Molecular Metabolism, Vol 5, Iss 5, Pp 328-339 (2016)
Molecular Metabolism
Molecular Metabolism
Objective Obesity represents a major risk factor for the development of type 2 diabetes mellitus, atherosclerosis and certain cancer entities. Treatment of obesity is hindered by the long-term maintenance of initially reduced body weight, and it rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8e91472136cbd017372aeae25beaf8
http://www.sciencedirect.com/science/article/pii/S2212877815002318
http://www.sciencedirect.com/science/article/pii/S2212877815002318
Autor:
Hella S. Brönneke, Emilio Tarcitano, Markus Heine, Peter Frommolt, Nils R. Hansmeier, Trieu-My Van, Marta Pradas-Juni, Jan Mauer, George A. Garinis, Deniz Bartsch, Sajjad Khani, Susanne Brodesser, Catherina Baitzel, Matteo Oliverio, Marcelo A. Mori, Elena Schmidt, Jens C. Brüning, Hans Hilpert, Sandra Konieczka, Jan-Wilhelm Kornfeld, Jörg Heeren
Publikováno v:
Nature Cell Biology. 18:328-336
Activation of brown adipose tissue (BAT) controls energy homeostasis in rodents and humans and has emerged as an innovative strategy for the treatment of obesity and type 2 diabetes mellitus. Here we show that ageing- and obesity-associated dysfuncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed436f6b2bb396c40a0b415a3485d74e
https://doi.org/10.1038/ncb3316
https://doi.org/10.1038/ncb3316
Autor:
Jens C. Brüning, Jens Alber, Oliver Hahn, Celine E. Riera, Eva Tsaousidou, Jonathan Halloran, Kevin M. Tharp, Andreas Stahl, Hella S. Brönneke, Linda Engström Ruud, Courtney M. Anderson, Pereira Mma, Patricia Follett, Andrew Dillin, Brigitte Hampel, Filho Cdm
Publikováno v:
Yearbook of Paediatric Endocrinology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54fd13381a04640759d5e30ab950951c
https://doi.org/10.1530/ey.15.11.10
https://doi.org/10.1530/ey.15.11.10
Autor:
Jens Alber, Johan Ruud, Jens C. Brüning, Hans Nissbrandt, Łukasz Szumiec, Hella S. Brönneke, Linda Engström Ruud, Anna Tokarska, Nasim Biglari, Jan Rodriguez Parkitna, Tatiana Korotkova, Änne Lautenschlager, Marcus Krüger, Gilad Silberberg, Hendrik Nolte, Przemysław Eligiusz Cieślak, Rachel N. Lippert, Martin E. Hess
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3182-3198.e9 (2019)
Summary: Variations in the human FTO gene have been linked to obesity and altered connectivity of the dopaminergic neurocircuitry. Here, we report that fat mass and obesity-associated protein (FTO) in dopamine D2 receptor-expressing medium spiny neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3184bbd69461558ca3f66a14eb7d379
https://pubmed.ncbi.nlm.nih.gov/31189104
https://pubmed.ncbi.nlm.nih.gov/31189104
Autor:
Barbara A. Pulido Guevara, Hella S. Brönneke, Claudia Dafinger, Jan-Robin Wagener, Thomas Benzing, Andras Bilkei-Gorzo, Andreas Zimmer, Martin Hoehne, Sabine Bertsch, Bernhard Schermer, Linus A. Völker, Barbara A. Maar, Heiko Schweizer
Publikováno v:
Genes, brain, and behavior. 17(8)
Adhesion molecules of the immunoglobulin superfamily (IgSF) are essential for neuronal synapse development across evolution and control various aspects of synapse formation and maturation. Neph2, also known as Kirrel3, is an IgSF adhesion molecule im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f59f6224ad92ff93b676bac3b4bf11
https://pubmed.ncbi.nlm.nih.gov/30133126
https://pubmed.ncbi.nlm.nih.gov/30133126
Autor:
Hella S. Brönneke, Eva Tsaousidou, Martin Pal, Claudia M. Wunderlich, Jens C. Brüning, Peter Kloppenburg, F. Thomas Wunderlich, Bengt F. Belgardt, Marc Schmidt-Supprian, Lars Paeger, Brigitte Hampel, Ursel Collienne
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1495-1506 (2014)
SummaryActivation of c-Jun N-terminal kinase 1 (JNK1)- and inhibitor of nuclear factor kappa-B kinase 2 (IKK2)-dependent signaling plays a crucial role in the development of obesity-associated insulin and leptin resistance not only in peripheral tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c786e1afc78e5592ac3e4610592612a5
http://www.sciencedirect.com/science/article/pii/S2211124714009140
http://www.sciencedirect.com/science/article/pii/S2211124714009140
Autor:
Roman-Ulrich Müller, Bernhard Schermer, Max C. Liebau, Heike Göbel, Volker Burst, Thomas Benzing, Martin Höhne, Linus A. Völker, Julia Heiss, Claudia Dafinger, Marc Albersmeyer, Malte P. Bartram, Hella S. Brönneke
Publikováno v:
Journal of Molecular Medicine. 91:739-748
MicroRNAs have emerged as essential regulators of gene expression and may play important roles in a variety of human disorders. To understand the role of microRNA-mediated gene regulation in the kidney, we deleted the microRNA-processing enzyme Dicer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd96b79511a458f8e1c5aee6d230d8d7
https://doi.org/10.1007/s00109-013-1000-x
https://doi.org/10.1007/s00109-013-1000-x
Autor:
Hella S. Brönneke, F. Thomas Wunderlich, Donald A. Morgan, Simon Hess, Sulay Tovar, Jens C. Brüning, A. Christine Hausen, P. Justus Ackermann, Nadine Evers, Hildegard Büning, Lars Paeger, Kamal Rahmouni, Brigitte Hampel, Peter Kloppenburg
Publikováno v:
Cell Metabolism
Cell Metabolism; Vol 18
Cell Metabolism; Vol 18
Summary Brown adipose tissue (BAT) is a critical regulator of glucose, lipid, and energy homeostasis, and its activity is tightly controlled by the sympathetic nervous system. However, the mechanisms underlying CNS-dependent control of BAT sympatheti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934d18372f98443178b69712222d0c6b