Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hella L. Aberson"'
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a grim disease with high mortality rates. Increased macrophage influx in PDAC is a common hallmark and associated with poor prognosis. Macrophages have high cellular plasticity, which can
Externí odkaz:
https://doaj.org/article/73d1e99142ce41bc93e5c3bcd4de4616
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 219 (2022)
Treatment of pancreatic ductal adenocarcinoma (PDAC), a dismal disease with poor survival rates, is hampered by the high prevalence of chemotherapy resistance. Resistance is accompanied by macrophage infiltration into the tumor microenvironment, and
Externí odkaz:
https://doaj.org/article/1c8065e6b82f41c1bf4788f4fc6063fc
Publikováno v:
Cells, Vol 10, Iss 9, p 2233 (2021)
CCAAT/enhancer-binding protein delta (C/EBPδ) is a member of the C/EBP family of transcription factors. According to the current paradigm, C/EBPδ potentiates cytokine production and modulates macrophage function thereby enhancing the inflammatory r
Externí odkaz:
https://doaj.org/article/7ab27c72921a40d9a26295346fef8aea
Publikováno v:
Cells
Volume 10
Issue 9
Cells, 10(9):2233. MDPI Multidisciplinary Digital Publishing Institute
Cells, Vol 10, Iss 2233, p 2233 (2021)
Volume 10
Issue 9
Cells, 10(9):2233. MDPI Multidisciplinary Digital Publishing Institute
Cells, Vol 10, Iss 2233, p 2233 (2021)
CCAAT/enhancer-binding protein delta (C/EBPδ) is a member of the C/EBP family of transcription factors. According to the current paradigm, C/EBPδ potentiates cytokine production and modulates macrophage function thereby enhancing the inflammatory r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d4eb8cf1b2197677271393c1437630
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
Background Pancreatic ductal adenocarcinoma (PDAC) is a grim disease with high mortality rates. Increased macrophage influx in PDAC is a common hallmark and associated with poor prognosis. Macrophages have high cellular plasticity, which can differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b268298f05bc9eabb436647e94aff146
https://doi.org/10.1186/s12885-020-07697-1
https://doi.org/10.1186/s12885-020-07697-1
Autor:
Maikel P. Peppelenbosch, Kan Chen, Gerrit K. J. Hooijer, Leonie Hartl, Joris J. T. H. Roelofs, C. Arnold Spek, Hella L. Aberson, JanWillem Duitman, Pratika Y. Hernanda, Ton Boerman, Mark P. G. Dings, Olivier R. Busch, Marc G. Besselink, Frederike Dijk, Maarten F. Bijlsma, Qiunwei Pan
Publikováno v:
Cancers, 12(9):2546, 1-21. Multidisciplinary Digital Publishing Institute (MDPI)
Hartl, L, Duitman, J, Aberson, H L, Chen, K, Dijk, F, Roelofs, J J T H, Dings, M P G, Hooijer, G K J, Hernanda, P Y, Pan, Q, Busch, O R, Besselink, M G H, Boerman, T, Peppelenbosch, M P, Bijlsma, M F & Spek, C A 2020, ' Ccaat/enhancer-binding protein delta (C/ebpδ) : A previously unrecognized tumor suppressor that limits the oncogenic potential of pancreatic ductal adenocarcinoma cells ', Cancers, vol. 12, no. 9, 2546, pp. 1-21 . https://doi.org/10.3390/cancers12092546
Cancers, Vol 12, Iss 2546, p 2546 (2020)
Cancers
Volume 12
Issue 9
Hartl, L, Duitman, J, Aberson, H L, Chen, K, Dijk, F, Roelofs, J J T H, Dings, M P G, Hooijer, G K J, Hernanda, P Y, Pan, Q, Busch, O R, Besselink, M G H, Boerman, T, Peppelenbosch, M P, Bijlsma, M F & Spek, C A 2020, ' Ccaat/enhancer-binding protein delta (C/ebpδ) : A previously unrecognized tumor suppressor that limits the oncogenic potential of pancreatic ductal adenocarcinoma cells ', Cancers, vol. 12, no. 9, 2546, pp. 1-21 . https://doi.org/10.3390/cancers12092546
Cancers, Vol 12, Iss 2546, p 2546 (2020)
Cancers
Volume 12
Issue 9
CCAAT/enhancer-binding protein &delta
(C/EBP&delta
) is a transcription factor involved in growth arrest and differentiation, which has consequently been suggested to harbor tumor suppressive activities. However, C/EBP&delta
over-expre
(C/EBP&delta
) is a transcription factor involved in growth arrest and differentiation, which has consequently been suggested to harbor tumor suppressive activities. However, C/EBP&delta
over-expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abcbf74028076458d10282193c980be5
https://pure.amc.nl/en/publications/ccaatenhancerbinding-protein-delta-cebp-a-previously-unrecognized-tumor-suppressor-that-limits-the-oncogenic-potential-of-pancreatic-ductal-adenocarcinoma-cells(2f283c0e-a342-4377-9e15-5dbfefda0a35).html
https://pure.amc.nl/en/publications/ccaatenhancerbinding-protein-delta-cebp-a-previously-unrecognized-tumor-suppressor-that-limits-the-oncogenic-potential-of-pancreatic-ductal-adenocarcinoma-cells(2f283c0e-a342-4377-9e15-5dbfefda0a35).html
Autor:
Cynthia Waasdorp, Onno J. de Boer, Cansu Tekin, Gerrit K. J. Hooijer, Hella L. Aberson, C. Arnold Spek, Maarten F. Bijlsma, Frederike Dijk
Publikováno v:
Cellular Oncology (Dordrecht)
Cellular oncology, 43(6), 1161-1174. IOS Press
Cellular oncology, 43(6), 1161-1174. IOS Press
Purpose Targeting tumor-infiltrating macrophages limits progression and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma (PDAC). Protease-activated receptor (PAR)1 drives monocyte/macrophage recruitment, and stromal ablation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba59aeae43e5d34e8e3ef2cfeb509cd4
https://pubmed.ncbi.nlm.nih.gov/32809114
https://pubmed.ncbi.nlm.nih.gov/32809114
Autor:
Carel J. M. van Noesel, Karla C. S. Queiroz, JanWillem Duitman, Dick J. Richel, Kun Shi, Johanna W. Wilmink, Hella L. Aberson, C. Arnold Spek
Publikováno v:
International Journal of Cancer. 135:2294-2304
Protease activated receptor (PAR)-1 expression in tumor cells is associated with disease progression and overall survival in a variety of cancers of epithelial origin; however, the importance of PAR-1 in the tumor microenvironment remains unexplored.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c3e2ed78eb00a0ab9af2c96b271fac
https://doi.org/10.1002/ijc.28726
https://doi.org/10.1002/ijc.28726
Autor:
C. A. Spek, Hella L. Aberson, Maikel P. Peppelenbosch, Gwenny M. Fuhler, R R Ruela-de-Sousa, Carmen Veríssima Ferreira, Karla C. S. Queiroz
Publikováno v:
Oncogene, 29(48), 6314-6322. Nature Publishing Group
The development of resistance against chemotherapy remains one of the major challenges in the clinical management of leukemia. There is still limited insight into the molecular mechanisms that maintain the chemotherapy-resistant phenotype, despite th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ffd2e1ddbfeae7aca7e631787b3507
https://doi.org/10.1038/onc.2010.375
https://doi.org/10.1038/onc.2010.375
Autor:
Karla C S, Queiroz, Kun, Shi, JanWillem, Duitman, Hella L, Aberson, Johanna W, Wilmink, Carel J M, van Noesel, Dick J, Richel, C Arnold, Spek
Publikováno v:
International journal of cancer. 135(10)
Protease activated receptor (PAR)-1 expression in tumor cells is associated with disease progression and overall survival in a variety of cancers of epithelial origin; however, the importance of PAR-1 in the tumor microenvironment remains unexplored.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa061592dc0368f0fbae5d63464da9b0
https://pubmed.ncbi.nlm.nih.gov/24436106
https://pubmed.ncbi.nlm.nih.gov/24436106