Výsledky vyhledávání - "Hella Bosteels"

Optimised mammalian expression through the coupling of codon adaptation with gene amplification: Maximum yields with minimum effort

Autor: George Stephen, Pamela Pegman, James D. Faulkner, Yuen-Ting Chim, Mark Uden, Hella Bosteels, Ekaterini Kotsopoulou, Susannah I. Thornhill

Publikováno v: Journal of Biotechnology. 146:186-193

Gene amplification methodologies are frequently employed for the generation of large quantities of recombinant proteins in mammalian cells. Although they usually guarantee very high yields, they are very time consuming. In addition, due to the large

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6e67b5d3cc45fbfe0aa93900dae20d
https://doi.org/10.1016/j.jbiotec.2010.02.004

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Cell line selection using the Duetz Microflask system

Autor: Jai Patel, Hella Bosteels, Sharon L White, Steve R. C. Warr, Yuen-Ting Chim

Publikováno v: BMC Proceedings, Vol 5, Iss Suppl 8, p P15 (2011)
BMC Proceedings

The identification of a small number of monoclonal antibody (mAb) producing candidate cell lines from the large number of clones generated post transfection is one of the bottlenecks of cell line development. Clone numbers are reduced significantly d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f7a6aa404b293f568655d9ee6c5074
https://doaj.org/article/4a8609477fc4429db1632c6f8b26361b

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