Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Helka Goos"'
Autor:
Senem Merve Fred, Liina Laukkanen, Cecilia A Brunello, Liisa Vesa, Helka Goos, Iseline Cardon, Rafael Moliner, Tanja Maritzen, Markku Varjosalo, Plinio C Casarotto, Eero Castrén
The activation of TRKB (tropomyosin-related kinase B), the receptor for brain-derived neurotrophic factor (BDNF), is a crucial step in brain plasticity. Several antidepressant drugs are reported to activate TRKB, and animals with compromised BDNF or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8f441abdb699370914dee823d7e816
Autor:
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here the authors identify 6703 and 1536 protein–protein interactions for 109 different human TFs through BioID and AP-MS analyses, respec
Externí odkaz:
https://doaj.org/article/67c33cf493234878a8d14411ff4708ab
Autor:
Farhana Jahan, Jan Koski, Diana Schenkwein, Seppo Ylä-Herttuala, Helka Göös, Sini Huuskonen, Markku Varjosalo, Pilvi Maliniemi, Judith Leitner, Peter Steinberger, Hans-Jörg Bühring, Kim Vettenranta, Matti Korhonen
Publikováno v:
Frontiers in Molecular Medicine, Vol 3 (2023)
Background: T cells that are genetically modified with chimeric antigen receptor (CAR) hold promise for immunotherapy of cancer. Currently, there are intense efforts to improve the safety and efficacy of CAR T cell therapies against liquid and solid
Externí odkaz:
https://doaj.org/article/99b6cf95a3c24eb697aeaeaaf665b268
Autor:
Jan Koski, Farhana Jahan, Annu Luostarinen, Diana Schenkwein, Seppo Ylä-Herttuala, Helka Göös, Hector Monzo, Päivi M. Ojala, Pilvi Maliniemi, Matti Korhonen
Publikováno v:
Frontiers in Molecular Medicine, Vol 2 (2022)
Background: T cells equipped with chimeric antigen receptors (CAR) have shown remarkable efficacy in targeting B lineage malignancies. Improvement of the CAR structure is needed, however, with a view to developing flexibly modifiable spacers that are
Externí odkaz:
https://doaj.org/article/3970041dcbc24907a9291c98de9f005e