Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Helisa H. Wippel"'
Publikováno v:
Chem Rev
Biological systems have evolved to utilize proteins to accomplish nearly all functional roles needed to sustain life. A majority of biological functions occur within the crowded environment inside cells and subcellular compartments where proteins exi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5491f6a9eed7dc0253f46819301cda
https://doi.org/10.1021/acs.chemrev.1c00223
https://doi.org/10.1021/acs.chemrev.1c00223
Publikováno v:
Molecular Omics. 17:503-516
RNA-binding proteins (RBPs) have conserved domains and consensus sequences that interact with RNAs and other proteins forming ribonucleoprotein (RNP) complexes. RNPs are involved in the regulation of several cellular processes, including transcriptio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81518806acf26eabef9f85a3988b77c5
https://doi.org/10.1039/d1mo00024a
https://doi.org/10.1039/d1mo00024a
Publikováno v:
Anal Chem
The study of protein structures and interactions is critical to understand their function. Chemical cross-linking of proteins with mass spectrometry (XL-MS) is a rapidly developing structural biology technique able to provide valuable insight into pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c614e283f8d6b34292860e3f5897b9
https://europepmc.org/articles/PMC8969885/
https://europepmc.org/articles/PMC8969885/
Publikováno v:
Anal Chem
Chemical cross-linking with mass spectrometry (XL-MS) has emerged as a useful technique for interrogating protein structures and interactions. When combined with quantitative proteomics strategies, protein conformational and interaction dynamics can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6f032c28fa5af00f81b8e2eac6f1cc
https://pubmed.ncbi.nlm.nih.gov/34882395
https://pubmed.ncbi.nlm.nih.gov/34882395
Autor:
Helisa H. Wippel, Juliane S. Malgarin, Lysangela R. Alves, Paulo C. Carvalho, Alexandre Haruo Inoue, Samuel Goldenberg, Felipe da Veiga Leprevost
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-12 (2019)
BMC Microbiology
BMC Microbiology
Background RNA-binding proteins (RBPs) are well known as key factors in gene expression regulation in eukaryotes. These proteins associate with mRNAs and other proteins to form mRNP complexes that ultimately determine the fate of target transcripts i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f6ff0840e17e0a39e46219ed39f38c
http://link.springer.com/article/10.1186/s12866-019-1505-8
http://link.springer.com/article/10.1186/s12866-019-1505-8
Publikováno v:
Curr Opin Chem Biol
Structural plasticity and dynamic protein–protein interactions are critical determinants of protein function within living systems. Quantitative chemical cross-linking with mass spectrometry (qXL-MS) is an emerging technology able to provide inform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4516526ab106543476aca26db982cd67
https://pubmed.ncbi.nlm.nih.gov/34393043
https://pubmed.ncbi.nlm.nih.gov/34393043
Publikováno v:
Protein Sci
Protein structure underpins functional roles in all biological processes; therefore, improved understanding of protein structures is of fundamental importance in nearly all biological and biomedical research areas. Traditional techniques such as X-ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd6b6918aca6b88531d3e4e2cd3a64d
https://europepmc.org/articles/PMC7980526/
https://europepmc.org/articles/PMC7980526/
Autor:
Tatiana de Arruda Campos Brasil de Souza, Juliana de Saldanha da Gama Fischer, Helisa H. Wippel, Paulo C. Carvalho, Rafaela Wassmandorf, Marlon D.M. Santos, Emanuella de Castro Andreassa
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics. 1869(2)
Apoptosis is a highly regulated process of cell death in metazoans. Therefore, understanding the biochemical changes associated with apoptosis-like death in Trypanosoma cruzi is key to drug development. PAC-1 was recently shown to induce apoptosis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73dd7e9047f37b1a5c9dbf1f5218f25
https://pubmed.ncbi.nlm.nih.gov/33285319
https://pubmed.ncbi.nlm.nih.gov/33285319
Autor:
Denildo César Amaral Veríssimo, Paulo C. Carvalho, Janaína M. Silva, Renata M. Santos, Marlon D.M. Santos, Gustavo A. R. Passos, Luis A.B. Borba, Juliana de Saldanha da Gama Fischer, Sergio Luiz Sprengel, Helisa H. Wippel, Fábio C. S. Nogueira
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Meningiomas are among the most common primary tumors of the central nervous system (CNS) and originate from the arachnoid or meningothelial cells of the meninges. Surgery is the first option of treatment, but depending on the location and invasion pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790f102e77bfe5f72c48ca2b56eeee10
https://doi.org/10.1038/s41598-020-67113-3
https://doi.org/10.1038/s41598-020-67113-3
Autor:
Lysangela R. Alves, Bruno Accioly Alves Romagnoli, Marlon D.M. Santos, Helisa H. Wippel, Newton Medeiros Vidal, Paulo C. Carvalho, Samuel Goldenberg, Bruna H. Marcon, Jimena Ferreira da Costa, Alexandre Haruo Inoue
Publikováno v:
RNA Biology. :1-13
Gene expression regulation in trypanosomes differs from other eukaryotes due to absence of transcriptional regulation for most of their genes. RNA-binding proteins (RBPs) associate with mRNAs and other regulatory proteins to form ribonucleoprotein co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef5f5c53468a23588f4d058a9dc514b
https://doi.org/10.1080/15476286.2018.1509660
https://doi.org/10.1080/15476286.2018.1509660