Výsledky vyhledávání - "Helios T. Leung"

Cytotoxic T Lymphocyte-associated Molecule-4, a High Avidity Receptor for CD80 and CD86, Contains an Intracellular Localization Motif in Its Cytoplasmic Tail

Autor: Helios T. Leung, Jeff Bradshaw, Jeffrey S. Cleaveland, Peter S. Linsley

Publikováno v: Journal of Biological Chemistry. 270:25107-25114

CD28 and CTLA-4, T cell receptors for B7-1 (CD80) and B7-2 (CD86) molecules on antigen-presenting cells, transmit costimulatory signals important for optimal T cell activation. Despite sharing sequence homology and common ligands, these receptors hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af31b4abb39caa80f18c7ed0bade7cc8
https://doi.org/10.1074/jbc.270.42.25107

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Binding Stoichiometry of the Cytotoxic T Lymphocyte-associated Molecule-4 (CTLA-4)

Autor: Gina Leytze, Steven G. Nadler, Alison R. Malacko, Peter S. Linsley, Helios T. Leung, Jeff Bradshaw, Mark R. Stebbins, Robert J. Peach, Hans Marquardt, William E. Brady, Shyh Yu Shaw, Jürgen Bajorath, Julie Rogers

Publikováno v: Journal of Biological Chemistry. 270:15417-15424

CD28 and CTLA-4 are homologous T cell receptors of the immunoglobulin (Ig) superfamily, which bind B7 molecules (CD80 and CD86) on antigen-presenting cells and transmit important costimulatory signals during T cell activation. Here we have investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c68c4aa830c35118d5d4e5df81b8543e
https://doi.org/10.1074/jbc.270.25.15417

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[21]Extrachromosomal substrates to study immunoglobulin heavy chain class switch recombination in mammalian B cells

Autor: Ming Jie Li, Helios T. Leung, Nancy Maizels

Publisher Summary This chapter discusses the use of extrachromosomal substrates to study immunoglobulin heavy chain class switch recombination in mammalian B cells. Immunoglobulin heavy chain class switch recombination is a regulated recombination ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::587e42d2046caa7fa4f710a52d94e355
https://doi.org/10.1016/s1067-2389(96)80054-9

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Targeting and Regulation of Immunoglobulin Gene Somatic Hypermutation and lsotype Switch Recombination

Autor: Markus Hengstschläger, Helios T. Leung, Nancy Maizels

Publikováno v: Progress in Nucleic Acid Research and Molecular Biology ISBN: 9780125400503

Publisher Summary This chapter discusses some of the recent work that has addressed the mechanisms of these two processes, with particular emphasis on the use of engineered constructs, to identify genetic elements critical to activation or targeting.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::122ee2df93db182ea3800c945183777b
https://doi.org/10.1016/s0079-6603(08)60811-9

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Copper(II) as a probe of the active centers of alkaline phosphatase

Autor: Claudio Luchinat, Joseph E. Coleman, Helios T. Leung, Ivano Bertini, Lucia Banci, Seymour H. Koenig, Maria Silvia Viezzoli

Publikováno v: Inorganic Chemistry. 28:352-358

Etude de l'alcaline phosphatase et des interactions avec le cuivre III, par mesure en spectrometrie RPE, de la susceptibilite magnetique, et de la dispersion RMN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8cc5b72130dc249eac8f1f2900817b47
https://doi.org/10.1021/ic00301a040

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