Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Helio K. Takahashi"'
Autor:
Erica V. De Castro Levatti, Marcos S. Toledo, Renata Watanabe Costa, Diana Bahia, Renato A. Mortara, Helio K. Takahashi, Anita H. Straus
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Inositol phosphorylceramide (IPC), the major sphingolipid in the genus Leishmania but not found in mammals, is considered a potentially useful target for chemotherapy against leishmaniasis. Leishmania (Viannia) braziliensis is endemic in Latin Americ
Externí odkaz:
https://doaj.org/article/82a8484b8a5b42cf907874ebbfecfac8
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 81, Iss 3, Pp 477-488 (2009)
Recently, glycosphingolipids have been attracting attention due to their role on biological systems as second messengers or modulators of signal transduction, affecting several events, which range from apoptosis to regulation of the cell cycle. In pa
Externí odkaz:
https://doaj.org/article/afff1393357047419f8f97eb2d342e6d
Autor:
Marcos S. Toledo, Steven B. Levery, Beau Bennion, Luciana L. Guimaraes, Sherry A. Castle, Rebecca Lindsey, Michelle Momany, Chaeho Park, Anita H. Straus, Helio K. Takahashi
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 8, Pp 1801-1824 (2007)
Acidic glycosphingolipid components were extracted from the opportunistic mycopathogen Aspergillus fumigatus and identified as inositol phosphorylceramide and glycosylinositol phosphorylceramides (GIPCs). Using nuclear magnetic resonance sppectroscop
Externí odkaz:
https://doaj.org/article/e5a2831ad9a74df58d1f7a5c5f7c9ae7
Autor:
Kelly A.G. Yoneyama, Ameria K. Tanaka, Thais G.V. Silveira, Helio K. Takahashi, Anita H. Straus
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 10, Pp 2171-2178 (2006)
Detergent-resistant membranes (DRMs) from Leishmania (Viannia) braziliensis promastigotes, insoluble in 1% Triton X-100 at 4°C, were fractionated by sucrose density gradient ultracentrifugation. They were composed of glycoinositolphospholipids (GIPL
Externí odkaz:
https://doaj.org/article/d32fa4b62fed41f1b040952dde5adcd2
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 5, Pp 797-806 (2000)
Major neutral glycosphingolipid components were extracted from Sporothrix schenckii, a dimorphic fungus exhibiting a hyphal saprophytic phase and a yeast parasitic phase responsible for chronic mycotic infections in mammalian hosts. These components,
Externí odkaz:
https://doaj.org/article/869add8d4ff444b68328a8a0d1e4ec13
Autor:
Larissa Vuitika, Andrea Senff-Ribeiro, Silvio Sanches Veiga, Olga Meiri Chaim, Daniele Chaves-Moreira, Raghuvir K. Arni, Helio K. Takahashi, Fernando Hitomi Matsubara, Mário T. Murakami, Marcos S. Toledo, Monika A. Coronado, Marcelo A. Lima, Helena B. Nader, Ícaro Putinhon Caruso
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1861:970-979
Brown spider phospholipases D from Loxosceles venoms are among the most widely studied toxins since they induce dermonecrosis, triggering inflammatory responses, increase vascular permeability, cause hemolysis, and renal failure. The catalytic (H12 a
Autor:
Marianna Boia-Ferreira, Dilza Trevisan-Silva, Silvio Sanches Veiga, Luiza Helena Gremski, Andrea Senff-Ribeiro, Fernando Hitomi Matsubara, Edgar J. Paredes-Gamero, Olga Meiri Chaim, M. M. Olivério, Aline Viana Bednaski, D. M. B. De Paula, Renan P. Cavalheiro, Helena B. Nader, Helio K. Takahashi, Marcos S. Toledo
Publikováno v:
Toxicon. 98:62-74
This is the first study on the hemolymph from a spider of the Loxosceles genus. These animals are responsible for a great number of envenomation cases worldwide. Several studies on Loxosceles venoms have been published, and the knowledge about the ve
Autor:
Diana Bahia, Renata Watanabe Costa, Anita H. Straus, Renato A. Mortara, Helio K. Takahashi, Erica Valadares de Castro Levatti, Marcos S. Toledo
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Frontiers in Microbiology
Frontiers in Microbiology
Inositol phosphorylceramide (IPC), the major sphingolipid expressed in the genus Leishmania but not expressed in mammals, is considered a potentially useful target for chemotherapy against leishmaniasis. Leishmania (Viannia) braziliensis is endemic i
Autor:
Marcos S. Toledo, Alberto José da Silva Duarte, Gil Benard, Vanessa Gomes Batista, Helio K. Takahashi, Maria José Soares Mendes-Giannini, Anita H. Straus
Publikováno v:
Mycopathologia. 178:153-162
Distinct glycolipid profiles are described in microorganisms, which have been shown to modulate the innate immune system. We tested the hypothesis that glycosphingolipids from Paracoccidioides brasiliensis have immunomodulatory properties on monocyte
Autor:
Paloma Korehisa Maza, Daisy Maria Bentes de Paula, Helio K. Takahashi, Erika Suzuki, Anita H. Straus, Priscila Oliveira, Marcos S. Toledo
Publikováno v:
Microbes and Infection. 14:1077-1085
Paracoccidioides brasiliensis is a pathogenic, dimorphic fungus that causes paracoccidioidomycosis, a systemic human mycosis that is highly prevalent in Latin America. In this study, we demonstrated that P. brasiliensis yeasts induced interleukin (IL