Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Helio C. Salgado"'
Autor:
Renata M. Lataro, Davi J. A. Moraes, Fabio N. Gava, Ana C. M. Omoto, Carlos A. A. Silva, Fernanda Brognara, Lais Alflen, Vânia Brazão, Rafaela Pravato Colato, José Clóvis do Prado, Anthony P. Ford, Helio C. Salgado, Julian F. R. Paton
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Despite medications, heart failure worsens with time with many patients dying within five years of diagnosis. Here the authors show that blocking purinergic receptors in the carotid body stops heart failure progression, improves its function, reduces
Externí odkaz:
https://doaj.org/article/e48a184e40354b858155e387d19d724e
Autor:
Mouzarllem B. Reis, Fernanda L. Rodrigues, Natalia Lautherbach, Alexandre Kanashiro, Carlos A. Sorgi, Alyne F. G. Meirelles, Carlos A. A. Silva, Karina F. Zoccal, Camila O. S. Souza, Simone G. Ramos, Alessandra K. Matsuno, Lenaldo B. Rocha, Helio C. Salgado, Luiz C. C. Navegantes, Ísis C. Kettelhut, Palmira Cupo, Luiz G. Gardinassi, Lúcia H. Faccioli
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Cardiac dysfunction is a major complication that precedes death after scorpion envenomation. Here, authors show that heart failure and mortality are caused by excessive acetylcholine release, which requires IL-1R-dependent PGE2 production. Dexamethas
Externí odkaz:
https://doaj.org/article/3824a55bb5ce42fc8ddfb1f913df0a2a
Autor:
Adriana B. Ribeiro, Camila B. de Araújo, Luiz Eduardo V. Silva, Rubens Fazan-Junior, Helio C. Salgado, Aline B. Ribeiro, Caroline V. Fortes, Frank L. Bueno, Viviane C. de Oliveira, Helena de F. O. Paranhos, Evandro Watanabe, Cláudia H. da Silva-Lovato
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Denture-related stomatitis (DS) is chronic multifactorial inflammation, strongly related to the presence of the biofilm that is the complex structure formed by microorganisms held together by a mucus-like matrix of carbohydrate th
Externí odkaz:
https://doaj.org/article/0fb716a928d7497f8680a26980f2403e
Autor:
Fernanda Machado Santos-Almeida, Gean Domingos-Souza, César A. Meschiari, Laura Campos Fávaro, Christiane Becari, Jaci A. Castania, Alexandre Lopes, Thiago M. Cunha, Davi J. A. Moraes, Fernando Q. Cunha, Luis Ulloa, Alexandre Kanashiro, Geisa C. S. V. Tezini, Helio C. Salgado
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Recent studies demonstrated a critical functional connection between the autonomic (sympathetic and parasympathetic) nervous and the immune systems. The carotid sinus nerve (CSN) conveys electrical signals from the chemoreceptors of the caro
Externí odkaz:
https://doaj.org/article/a23664769526447d8ebaae9047414149
Autor:
Fernanda P Prado, Daniele O Dos Santos, Valdecir Blefari, Carlos A Silva, Juliano Machado, Isis do Carmo Kettelhut, Simone G Ramos, Marcelo Dias Baruffi, Helio C Salgado, Cibele M Prado
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189469 (2017)
Hypertension causes cardiac hypertrophy, one of the most important risk factors for heart failure (HF). Despite the importance of cardiac hypertrophy as a risk factor for the development of HF, not all hypertrophied hearts will ultimately fail. Alter
Externí odkaz:
https://doaj.org/article/49989d8ff21f4f7d975406a3fe545151
Publikováno v:
The FASEB Journal. 36
Autor:
Rafael R. Santos, Thais M. Silva, Luiz E. V. Silva, Alan L. Eckeli, Helio C. Salgado, Rubens Fazan
Publikováno v:
The FASEB Journal. 36
Autor:
Diogo A. Guimarães, Nayara S. S. Aquino, Cibele Rocha-Resende, Itamar C. G. Jesus, Mario Morais Silva, Sérgio A. Scalzo, Roberta Cristelli Fonseca, Marina T. Durand, Vanessa Pereira, Geisa C. S. V. Tezini, André Oliveira, Vania F. Prado, Ivanita Stefanon, Helio C. Salgado, Marco Antônio Máximo Prado, Raphael E. Szawka, Silvia Guatimosim
Publikováno v:
American journal of physiology. Cell physiology. 322(4)
It is well known that cholinergic hypofunction contributes to cardiac pathology, yet, the mechanisms involved remain unclear. Our previous study has shown that genetically engineered model of cholinergic deficit, the vesicular acetylcholine transport
Autor:
João Paulo J. Sabino, Mauro de Oliveira, Humberto Giusti, Mogens Lesner Glass, Helio C. Salgado, Rubens Fazan Jr.
Publikováno v:
Clinics, Vol 68, Iss 3, Pp 395-399 (2013)
OBJECTIVE: Chemoreceptors play an important role in the autonomic modulation of circulatory and ventilatory responses to changes in arterial O2 and/or CO2. However, studies evaluating hemodynamic responses to hypoxia and hypercapnia in rats have show
Externí odkaz:
https://doaj.org/article/0bfa795920de4db781641b9fc915c41e
Autor:
Audrys G. Pauza, Pratik Thakkar, Tatjana Tasic, Igor Felippe, Paul Bishop, Michael P. Greenwood, Kristina Rysevaite-Kyguoliene, Julia Ast, Johannes Broichhagen, David J. Hodson, Helio C. Salgado, Dainius H. Pauza, Nina Japundzic-Zigon, Julian F.R. Paton, David Murphy
Publikováno v:
Circulation Research
Circ Res
Circ Res
Background: Aberrant sympathetic nerve activity exacerbates cardiovascular risk in hypertension and diabetes, which are common comorbidities, yet clinically sympathetic nerve activity remains poorly controlled. The hypertensive diabetic state is asso