Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Helin Sertkaya"'
Autor:
Helin Sertkaya, Laura Hidalgo, Mattia Ficarelli, Dorota Kmiec, Adrian W. Signell, Sadfer Ali, Hannah Parker, Harry Wilson, Stuart J.D. Neil, Michael H. Malim, Conrad A. Vink, Chad M. Swanson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 147-157 (2021)
The antiviral protein ZAP binds CpG dinucleotides in viral RNA to inhibit replication. This has likely led to the CpG suppression observed in many RNA viruses, including retroviruses. Sequences added to retroviral vector genomes, such as internal pro
Externí odkaz:
https://doaj.org/article/f3e41db9b0604b7a84a4efc502459f51
Autor:
Helin Sertkaya, Mattia Ficarelli, Nathan P. Sweeney, Hannah Parker, Conrad A. Vink, Chad M. Swanson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Many lentiviral vectors used for gene therapy are derived from HIV-1. An optimal vector genome would include only the viral sequences required for transduction efficiency and gene expression to minimize the amount of foreign sequence inserte
Externí odkaz:
https://doaj.org/article/9e4cd1425eb842c698f1446a5655b4b4
Autor:
Maria Jose Lista, Pedro M Matos, Thomas J A Maguire, Kate Poulton, Elena Ortiz-Zapater, Robert Page, Helin Sertkaya, Ana M Ortega-Prieto, Edward Scourfield, Aoife M O'Byrne, Clement Bouton, Ruth E Dickenson, Mattia Ficarelli, Jose M Jimenez-Guardeño, Mark Howard, Gilberto Betancor, Rui Pedro Galao, Suzanne Pickering, Adrian W Signell, Harry Wilson, Penelope Cliff, Mark Tan Kia Ik, Amita Patel, Eithne MacMahon, Emma Cunningham, Katie Doores, Monica Agromayor, Juan Martin-Serrano, Esperanza Perucha, Hannah E Mischo, Manu Shankar-Hari, Rahul Batra, Jonathan Edgeworth, Mark Zuckerman, Michael H Malim, Stuart Neil, Rocio Teresa Martinez-Nunez
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256813 (2021)
There is a worldwide need for reagents to perform SARS-CoV-2 detection. Some laboratories have implemented kit-free protocols, but many others do not have the capacity to develop these and/or perform manual processing. We provide multiple workflows f
Externí odkaz:
https://doaj.org/article/3f12b4eed48146f8a3869115c7009c11
Autor:
Hannah Parker, Sadfer Ali, Chad M. Swanson, Dorota Kmiec, Conrad A. Vink, Michael H. Malim, Laura Hidalgo, Harry Wilson, Mattia Ficarelli, Stuart J. D. Neil, Adrian W. Signell, Helin Sertkaya
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 147-157 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
The antiviral protein ZAP binds CpG dinucleotides in viral RNA to inhibit replication. This has likely led to the CpG suppression observed in many RNA viruses, including retroviruses. Sequences added to retroviral vector genomes, such as internal pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371e288c4ea5f5d7a8619a9f4d672c34
http://www.sciencedirect.com/science/article/pii/S2329050121001340
http://www.sciencedirect.com/science/article/pii/S2329050121001340
Autor:
Deborah J. Hart, Neophytos Kouphou, Michael H. Malim, Philippa M. Wells, Kate Poulton, Thomas J. A. Maguire, Ruth C. E. Bowyer, Myra O. McClure, Sebastien Ourselin, Carolina Rosadas, Helin Sertkaya, Rocio Martinez Nunez, Maria Jose Lista, Joan Capedevilla-pujol, Katie J. Doores, Richard S. Tedder, Sam Acors, Ruth E Dickenson, Jeffrey Seow, Carl Graham, Jonathan Wolf, Pedro M. Matos, Oliver Hemmings, Matthew A. Brown, Stuart J. D. Neil, Kathryn J. A. Steel, Edward J. Scourfield, Claire J. Steves, Simon Couvreur, Aoife M O'Byrne, Tim D. Spector
Publikováno v:
Journal of Infection
The Journal of Infection
The Journal of Infection
BackgroundUnderstanding of the true asymptomatic rate of infection of SARS-CoV-2 is currently limited, as is understanding of the population-based seroprevalence after the first wave of COVID-19 within the UK. The majority of data thus far come from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ade4283ae1641a5d59d8226ac405983
https://doi.org/10.1101/2020.07.29.20162701
https://doi.org/10.1101/2020.07.29.20162701
Autor:
Gilberto Betancor, Mark Zuckerman, Adrian W. Signell, Ana Maria Ortega-Prieto, Aoife M O'Byrne, Mark Tan Kia Ik, Hannah E. Mischo, Ruth E Dickenson, Mark Howard, Robert Page, Eithne MacMahon, Pedro M. Matos, Michael H. Malim, Clement Bouton, Amita Patel, Helin Sertkaya, Suzanne Pickering, Emma J. A. Cunningham, Jose M. Jimenez-Guardeño, Elena Ortiz-Zapater, Edward J. Scourfield, Harry Wilson, Thomas J. A. Maguire, Esperanza Perucha, Mattia Ficarelli, Stuart J. D. Neil, Jonathan D. Edgeworth, Katie J. Doores, Juan Martin-Serrano, Kate Poulton, Penelope R. Cliff, Manu Shankar-Hari, Rocio T. Martinez-Nunez, Monica Agromayor, Rahul Batra, Maria Jose Lista, Rui Pedro Galão
Publikováno v:
PLoS ONE
medRxiv
article-version (status) pre
article-version (number) 4
PLoS ONE, Vol 16, Iss 9, p e0256813 (2021)
medRxiv
article-version (status) pre
article-version (number) 4
PLoS ONE, Vol 16, Iss 9, p e0256813 (2021)
There is a worldwide shortage of reagents to perform detection of SARS-2. Many clinical diagnostic laboratories rely on commercial platforms that provide integrated end-to-end solutions. While this provides established robust pipelines, there is a cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203e18ccaa0354301a9769b49a2eeb16
https://doi.org/10.1101/2020.04.22.20074351
https://doi.org/10.1101/2020.04.22.20074351