Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Helia B. Schonthaler"'
Autor:
Elisabeth Glitzner, Ana Korosec, Patrick M Brunner, Barbara Drobits, Nicole Amberg, Helia B Schonthaler, Tamara Kopp, Erwin F Wagner, Georg Stingl, Martin Holcmann, Maria Sibilia
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 10, Pp 1312-1327 (2014)
Abstract Several subtypes of APCs are found in psoriasis patients, but their involvement in disease pathogenesis is poorly understood. Here, we investigated the contribution of Langerhans cells (LCs) and plasmacytoid DCs (pDCs) in psoriasis. In human
Externí odkaz:
https://doaj.org/article/0deedda89e6943ffb42d4008249c2cbb
Autor:
Dirk A Kleinjan, Ruth M Bancewicz, Philippe Gautier, Ralf Dahm, Helia B Schonthaler, Giuseppe Damante, Anne Seawright, Ann M Hever, Patricia L Yeyati, Veronica van Heyningen, Pedro Coutinho
Publikováno v:
PLoS Genetics, Vol 4, Iss 2, p e29 (2008)
Gene duplication is a major driver of evolutionary divergence. In most vertebrates a single PAX6 gene encodes a transcription factor required for eye, brain, olfactory system, and pancreas development. In zebrafish, following a postulated whole-genom
Externí odkaz:
https://doaj.org/article/9a26fc9a624447109c3148e66075d9ac
Autor:
María Abad, H Li, Adelaida R. Palla, Manuel Serrano, Helia B. Schonthaler, Erwin F. Wagner, Orlando Domínguez, Daniela Piazzolla
Publikováno v:
Oncogene
NANOG is a key transcription factor for pluripotency in embryonic stem cells. The analysis of NANOG in human cells is confounded by the presence of multiple and highly similar paralogs. In particular, there are three paralogs encoding full-length pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adefb50ba74d43cb9d257f6437c78f0
https://doi.org/10.1038/onc.2013.196
https://doi.org/10.1038/onc.2013.196
Autor:
Juan Guinea-Viniegra, Helia B. Schonthaler, Maria Sibilia, Latifa Bakiri, Harald Scheuch, Erwin F. Wagner, Denes Hnisz, Martin Holcmann, Rainer Zenz
Publikováno v:
Genes & Development. 23:2663-2674
Inducible epidermal deletion ofJunBandc-Junin adult mice causes a psoriasis-like inflammatory skin disease. Increased levels of the proinflammatory cytokine TNFα play a major role in this phenotype. Here we define the underlying molecular mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286cb1df55cdb343d171f3007176ea45
https://doi.org/10.1101/gad.543109
https://doi.org/10.1101/gad.543109
Publikováno v:
Acta Ophthalmologica. 86:655-665
Purpose: Collagen fibrils and proteoglycans are the main components of the corneal extracellular matrix and corneal transparency depends crucially on their proper arrangement. In the present study, we investigated the formation of collagen fibrils an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89684da65f2da989bf6f1e948601ec13
https://doi.org/10.1111/j.1600-0420.2007.01135.x
https://doi.org/10.1111/j.1600-0420.2007.01135.x
Autor:
Lukas Kenner, Helia B. Schonthaler, Harald Scheuch, Erwin F. Wagner, Rainer Zenz, Josef M. Penninger, Arabella Meixner
Publikováno v:
Nature Cell Biology. 10:1003-1011
Mice that lack JunB in epidermal cells are born with normal skin; however, keratinocytes hyperproliferate in vitro and on TPA treatment in vivo. Loss of JunB expression in the epidermis of adult mice affects the skin, the proliferation of haematopoie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd0c49d48d901dff8cae8deaabf40f7
https://doi.org/10.1038/ncb1761
https://doi.org/10.1038/ncb1761
Autor:
Oliver Biehlmaier, Yuri V. Makhankov, Heinz Schwarz, Helia B. Schonthaler, Oliver Rinner, Robert Geisler, Stephan C.F. Neuhauss, Ralf Dahm, Valerie C. Fleisch, Ronja Bahadori
Publikováno v:
Development. 135:387-399
The trafficking of intracellular vesicles is essential for a number of cellular processes and defects in this process have been implicated in a wide range of human diseases. We identify the zebrafish mutant lbk as a novel model for such disorders. lb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed376472db25a603c403a1ea6949817a
https://doi.org/10.1242/dev.006098
https://doi.org/10.1242/dev.006098
Autor:
Johannes von Lintig, Andrea Isken, Andreas Mader, Vitus Oberhauser, Stephan C.F. Neuhauss, Helia B. Schonthaler, Marcin Golczak, Oliver Rinner, Matthias Gesemann, Johanna M. Lampert, Krzysztof Palczewski, Oliver Biehlmaier
Publikováno v:
European Journal of Neuroscience. 26:1940-1949
An enzyme-based cyclic pathway for trans to cis isomerization of the chromophore of visual pigments (11-cis-retinal) is intrinsic to vertebrate cone and rod vision. This process, called the visual cycle, is mostly characterized in rod-dominated retin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f77dccf53445426d61f9fc215cc4b982
https://doi.org/10.1111/j.1460-9568.2007.05801.x
https://doi.org/10.1111/j.1460-9568.2007.05801.x
Autor:
Raquel Navarro, Erwin Tschachler, Esteban Daudén, M.J. Concha-Garzón, Erwin F. Wagner, Helia B. Schonthaler, Juan Guinea-Viniegra, Yolanda Delgado, Susanna Obad, Maria Jimenez
Publikováno v:
Science Translational Medicine
Psoriasis is a common inflammatory skin disease with limited treatment options that is characterized by a complex interplay between keratinocytes, immune cells, and inflammatory mediators. MicroRNAs (miRNAs) are regulators of gene expression and play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6938f8e15ff2747054b20b8c4a9b4003
https://doi.org/10.1126/scitranslmed.3008089
https://doi.org/10.1126/scitranslmed.3008089
Autor:
Raquel Navarro, Erwin F. Wagner, Juan Guinea-Viniegra, Ana Guío-Carrión, Helia B. Schonthaler, Isabel Ruppen, Pilar Ximénez-Embún, Keith Ashman, Stefanie K. Wculek, Nancy Hogg
Publikováno v:
Immunity
SummaryPsoriasis is a common heterogeneous inflammatory skin disease with a complex pathophysiology and limited treatment options. Here we performed proteomic analyses of human psoriatic epidermis and found S100A8-S100A9, also called calprotectin, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc091caa429bf3695b6fc4ebd4f2788