Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Heli Tiensuu"'
Autor:
Pinja Tissarinen, Heli Tiensuu, Antti M. Haapalainen, Eveliina Ronkainen, Liisa Laatio, Marja Vääräsmäki, Hanna Öhman, Mikko Hallman, Mika Rämet
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Currently, there are no accurate means to predict spontaneous preterm birth (SPTB). Recently, we observed low expression of alpha-1 antitrypsin (AAT) in SPTB placentas. Present aim was to compare the concentrations of maternal serum AAT in p
Externí odkaz:
https://doaj.org/article/bf2b0d178d8d43c3b6ecda17d5dda599
Autor:
Anu Pasanen, Minna K Karjalainen, FinnGen, Ge Zhang, Heli Tiensuu, Antti M Haapalainen, Marja Ojaniemi, Bjarke Feenstra, Bo Jacobsson, Aarno Palotie, Hannele Laivuori, Louis J Muglia, Mika Rämet, Mikko Hallman
Publikováno v:
PLoS Genetics, Vol 19, Iss 10, p e1010982 (2023)
BackgroundPreterm birth (MethodsWe conducted a genome-wide meta-analysis of gestational duration and spontaneous preterm birth in 68,732 and 98,370 European mothers, respectively.ResultsThe meta-analysis detected 15 loci associated with gestational d
Externí odkaz:
https://doaj.org/article/f14300073a8b497a870ffbbe353c0e10
Human placental proteomics and exon variant studies link AAT/SERPINA1 with spontaneous preterm birth
Autor:
Heli Tiensuu, Antti M. Haapalainen, Pinja Tissarinen, Anu Pasanen, Tomi A. Määttä, Johanna M. Huusko, Steffen Ohlmeier, Ulrich Bergmann, Marja Ojaniemi, Louis J. Muglia, Mikko Hallman, Mika Rämet
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract Background Preterm birth is defined as live birth before 37 completed weeks of pregnancy, and it is a major problem worldwide. The molecular mechanisms that lead to onset of spontaneous preterm birth are incompletely understood. Prediction a
Externí odkaz:
https://doaj.org/article/04242490e6fe48ffa80aef8110c60e46
Autor:
Johanna M. Huusko, Heli Tiensuu, Antti M. Haapalainen, Anu Pasanen, Pinja Tissarinen, Minna K. Karjalainen, Ge Zhang, Kaare Christensen, Kelli K. Ryckman, Bo Jacobsson, Jeffrey C. Murray, Stephen F. Kingsmore, Mikko Hallman, Louis J. Muglia, Mika Rämet
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Heat shock proteins are involved in the response to stress including activation of the immune response. Elevated circulating heat shock proteins are associated with spontaneous preterm birth (SPTB). Intracellular heat shock proteins act as m
Externí odkaz:
https://doaj.org/article/f305df8cd6b34e51b15c496289d931fa
Autor:
Heli Tiensuu, Antti M Haapalainen, Minna K Karjalainen, Anu Pasanen, Johanna M Huusko, Riitta Marttila, Marja Ojaniemi, Louis J Muglia, Mikko Hallman, Mika Rämet
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008107 (2019)
Spontaneous preterm birth (SPTB) is the leading cause of neonatal death and morbidity worldwide. Both maternal and fetal genetic factors likely contribute to SPTB. We performed a genome-wide association study (GWAS) on a population of Finnish origin
Externí odkaz:
https://doaj.org/article/40722b32dea848e9ab80e286121da752
Autor:
Jeffrey C. Murray, Kaare Christensen, Johanna M. Huusko, Ge Zhang, Mika Rämet, Antti M. Haapalainen, Anu Pasanen, Mikko Hallman, Minna K. Karjalainen, Bo Jacobsson, Pinja Tissarinen, Heli Tiensuu, Kelli K. Ryckman, Louis J. Muglia, Stephen F. Kingsmore
Publikováno v:
Scientific Reports
Huusko, J M, Tiensuu, H, Haapalainen, A M, Pasanen, A, Tissarinen, P, Karjalainen, M K, Zhang, G, Christensen, K, Ryckman, K K, Jacobsson, B, Murray, J C, Kingsmore, S F, Hallman, M, Muglia, L J & Rämet, M 2021, ' Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth ', Scientific Reports, vol. 11, 17115 . https://doi.org/10.1038/s41598-021-96374-9
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Huusko, J M, Tiensuu, H, Haapalainen, A M, Pasanen, A, Tissarinen, P, Karjalainen, M K, Zhang, G, Christensen, K, Ryckman, K K, Jacobsson, B, Murray, J C, Kingsmore, S F, Hallman, M, Muglia, L J & Rämet, M 2021, ' Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth ', Scientific Reports, vol. 11, 17115 . https://doi.org/10.1038/s41598-021-96374-9
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Heat shock proteins are involved in the response to stress including activation of the immune response. Elevated circulating heat shock proteins are associated with spontaneous preterm birth (SPTB). Intracellular heat shock proteins act as multifunct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed011d2f316be5a08f0d88c3400f0a0b
https://hdl.handle.net/11250/2988984
https://hdl.handle.net/11250/2988984
