Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Heli Siljander"'
Autor:
Jelena Štšepetova, Kärt Simre, Aili Tagoma, Oivi Uibo, Aleksandr Peet, Heli Siljander, Vallo Tillmann, Mikael Knip, Reet Mändar, Raivo Uibo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The potential impact of the composition of maternal breast milk is poorly known in children who develop celiac disease (CD). The aim of our study was to compare the microbiota composition and the concentrations of immune markers in breast mi
Externí odkaz:
https://doaj.org/article/3e56ef89fd904d05b47e048afbb928f7
Autor:
Santosh Lamichhane, Heli Siljander, Marja Salonen, Terhi Ruohtula, Suvi M. Virtanen, Jorma Ilonen, Tuulia Hyötyläinen, Mikael Knip, Matej Orešič
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
BackgroundCurrent evidence suggests that the composition of infant formula (IF) affects the gut microbiome, intestinal function, and immune responses during infancy. However, the impact of IF on circulating lipid profiles in infants is still poorly u
Externí odkaz:
https://doaj.org/article/e9aeef66ed1d4f208641a12cb5a2e4e4
Autor:
Santosh Lamichhane, Heli Siljander, Daniel Duberg, Jarno Honkanen, Suvi M. Virtanen, Matej Orešič, Mikael Knip, Tuulia Hyötyläinen
Publikováno v:
Environment International, Vol 157, Iss , Pp 106855- (2021)
The composition of human breast milk is highly variable inter- and intra-individually. Environmental factors are suspected to contribute to such compositional variation, however, their impact on breast milk composition is currently poorly understood.
Externí odkaz:
https://doaj.org/article/0e81b88b49cf48e58d7f27213c5ce653
Publikováno v:
EBioMedicine, Vol 46, Iss , Pp 512-521 (2019)
The steep increase in the incidence of type 1 diabetes (T1D), in the Western world after World War II, cannot be explained solely by genetic factors but implies that this rise must be due to crucial interactions between predisposing genes and environ
Externí odkaz:
https://doaj.org/article/f2f9adbacf124246abd491f26c9992c0
Autor:
Jelena Štšepetova, Kärt Simre, Aili Tagoma, Oivi Uibo, Aleksandr Peet, Heli Siljander, Vallo Tillmann, Mikael Knip, Reet Mändar, Raivo Uibo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/12043e7518284325a662e8b88afa6419
Autor:
Terhi Ruohtula, Anita Kondrashova, Jussi Lehtonen, Sami Oikarinen, Anu-Maaria Hämäläinen, Onni Niemelä, Aleksandr Peet, Vallo Tillmann, Janne K. Nieminen, Jorma Ilonen, Mikael Knip, Outi Vaarala, Heikki Hyöty, the DIABIMMUNE Study Group, Taina Härkönen, Samppa Ryhänen, Heli Siljander, Katriina Koski, Matti Koski, Janne Nieminen, Anne Ormisson, Valentina Ulich, Elena Kuzmicheva, Sergei Mokurov, Svetlana Markova, Svetlana Pylova, Marina Isakova, Elena Shakurova, Vladimir Petrov, Natalya V. Dorshakova, Tatyana Karapetyan, Tatyana Varlamova, Minna Kiviniemi, Kristi Alnek, Helis Janson, Raivo Uibo, Tiit Salum, Erika von Mutius, Juliane Weber, Helena Ahlfors, Henna Kallionpää, Essi Laajala, Riitta Lahesmaa, Harri Lähdesmäki, Robert Moulder, Hanna Honkanen, Hermie J. M. Harmsen, Marcus C. De Goffau, Gjalt Welling, Kirsi Alahuhta, Suvi M. Virtanen
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Early childhood infections have been implicated in the development of immune-mediated diseases, such as allergies, asthma, and type 1 diabetes. We set out to investigate the immunomodulatory effects of early viral infections experienced before the ag
Externí odkaz:
https://doaj.org/article/ca21e7c29d554bd19737315e49f69bb8
Autor:
Aidan McGlinchey, Tim Sinioja, Santosh Lamichhane, Partho Sen, Johanna Bodin, Heli Siljander, Alex M. Dickens, Dawei Geng, Cecilia Carlsson, Daniel Duberg, Jorma Ilonen, Suvi M. Virtanen, Hubert Dirven, Hanne Friis Berntsen, Karin Zimmer, Unni C. Nygaard, Matej Orešič, Mikael Knip, Tuulia Hyötyläinen
Publikováno v:
Environment International, Vol 143, Iss , Pp 105935- (2020)
In the last decade, increasing incidence of type 1 diabetes (T1D) stabilized in Finland, a phenomenon that coincides with tighter regulation of perfluoroalkyl substances (PFAS). Here, we quantified PFAS to examine their effects, during pregnancy, on
Externí odkaz:
https://doaj.org/article/a57c59559b8749bc97a4d90ab4a1fb89
Autor:
Terhi Ruohtula, Marcus C. de Goffau, Janne K. Nieminen, Jarno Honkanen, Heli Siljander, Anu-Maaria Hämäläinen, Aleksandr Peet, Vallo Tillmann, Jorma Ilonen, Onni Niemelä, Gjalt W. Welling, Mikael Knip, Hermie J. Harmsen, Outi Vaarala
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Recent studies suggest that the cross-talk between the gut microbiota and human immune system during the first year of life is an important regulator of the later development of atopic diseases. We explored the changes in the gut microbiota, blood re
Externí odkaz:
https://doaj.org/article/22ada90bbffd451f87d1d20455941039
Autor:
Santosh Lamichhane, Linda Ahonen, Thomas Sparholt Dyrlund, Alex M. Dickens, Heli Siljander, Heikki Hyöty, Jorma Ilonen, Jorma Toppari, Riitta Veijola, Tuulia Hyötyläinen, Mikael Knip, Matej Oresic
Publikováno v:
Biomolecules, Vol 9, Iss 1, p 33 (2019)
Previous studies suggest that children who progress to type 1 diabetes (T1D) later in life already have an altered serum lipid molecular profile at birth. Here, we compared cord blood lipidome across the three study groups: children who progressed to
Externí odkaz:
https://doaj.org/article/6888fb5d551c43e3be7f319dce800a8d
Autor:
Katariina Koivusaari, Sari Niinistö, Jaakko Nevalainen, Jarno Honkanen, Terhi Ruohtula, Mirva Koreasalo, Suvi Ahonen, Mari Åkerlund, Heli Tapanainen, Heli Siljander, Maija E. Miettinen, Tapani Alatossava, Jorma Ilonen, Outi Vaarala, Mikael Knip, Suvi M. Virtanen
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition. 76:822-829