Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Heli Kukko"'
Purpose: Merkel cell carcinoma (MCC) is rare skin cancer that is often associated with Merkel cell polyomavirus (MCPyV) infection. Polyomaviruses repress tumor suppressor proteins, thus influencing cell-cycle progression, but the effect of MCPyV on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b6a956aab5855ada7869a7b99f88c0
https://doi.org/10.1158/1078-0432.c.6519617.v1
https://doi.org/10.1158/1078-0432.c.6519617.v1
Supplementary Data 3 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c57101311136c84d174b68e180cb705
https://doi.org/10.1158/1078-0432.22443020
https://doi.org/10.1158/1078-0432.22443020
Supplementary Data 2 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d64812a4df28c81ff8f7dff55abf1b8
https://doi.org/10.1158/1078-0432.22443023
https://doi.org/10.1158/1078-0432.22443023
Supplementary Data 1 from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2651701d6ae52a79db1b68033cb2389
https://doi.org/10.1158/1078-0432.22443026.v1
https://doi.org/10.1158/1078-0432.22443026.v1
Autor:
Heli Kukko, Tom Böhling, Virve Koljonen, Arun Pokhrel, Risto Sankila, Eero Pukkala, Caj Haglund, Erkki Tukiainen
Publikováno v:
European Journal of Cancer. 48:737-742
Background Merkel cell carcinoma (MCC) is a rare malignancy of the skin, and its incidence is reported to be rising. The purpose of this study was to calculate its incidence and survival ratios, and to describe the clinical characteristics of Merkel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef663e41e5fe77d3b242c4e664240f3
https://doi.org/10.1016/j.ejca.2011.06.001
https://doi.org/10.1016/j.ejca.2011.06.001
Autor:
Risto Sankila, Heikki Joensuu, Tom Böhling, Heli Kukko, Virve Koljonen, Harri Sihto, Marika Waltari
Publikováno v:
International Journal of Cancer. 129:619-628
Most Merkel cell carcinomas (MCCs) contain Merkel cell polyomavirus (MCPyV) DNA, and the virus likely has a pivotal role in tumor pathogenesis. p53 and the KIT receptor tyrosine kinase have also been implicated in MCC pathogenesis, but little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6381ca411bbff13352742aaad0a1b637
https://doi.org/10.1002/ijc.25720
https://doi.org/10.1002/ijc.25720
Publikováno v:
Modern Pathology. 23:1151-1156
This study investigated vascular and especially lymphovascular invasion in primary Merkel cell carcinoma and its value as a prognostic factor. Paraffin-embedded blocks prepared from tumor samples obtained from 126 patients diagnosed with Merkel cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d04448aa13895d93416fc2c6ba16371
https://doi.org/10.1038/modpathol.2010.100
https://doi.org/10.1038/modpathol.2010.100
Autor:
Erkki Tukiainen, Virve Koljonen, Heikki Joensuu, Heli Kukko, Harri Sihto, Helka Sahi, Tom Böhling
Publikováno v:
European Journal of Plastic Surgery. 33:349-353
Merkel cell carcinoma (MCC) is a rare neuroendocrine carcinoma typically affecting the elderly. Only 5% to 10% of the patients are younger than 50 years at the time of the diagnosis. The purpose of this study was to compare the tumour and disease cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72f03907015152497b0571f1800c8161
https://doi.org/10.1007/s00238-010-0429-1
https://doi.org/10.1007/s00238-010-0429-1
Autor:
Heikki Joensuu, Risto Sankila, Eero Pukkala, Virve Koljonen, Erkki Tukiainen, Heli Kukko, Tom Böhling, Harri Sihto
Publikováno v:
British Journal of Cancer
Background: Immunosuppression and Merkel-cell polyomavirus (MCPyV) infection may have a role in the pathogenesis of Merkel-cell carcinoma (MCC), a rare neuroendocrine carcinoma of the skin. Methods: We studied incidence of chronic lymphocytic leukaem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5e7759170f5246f89c2eb851651e34
https://doi.org/10.1038/sj.bjc.6605306
https://doi.org/10.1038/sj.bjc.6605306
Publikováno v:
University of Helsinki
Summary We present a 27-year-old pregnant woman with Merkel cell carcinoma on the forehead. In early pregnancy, the lesion was excised as an epidermal cyst. It was only after recurrence that a diagnosis of Merkel cell carcinoma was made. Sentinel-nod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cc3d1bf7097cd01de7da6191b76d00
https://doi.org/10.1016/j.bjps.2007.06.016
https://doi.org/10.1016/j.bjps.2007.06.016