Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Heli K Vari"'
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47121 (2012)
Sequence-specific RNA binding proteins can induce the degradation of mRNAs through their ability to recruit proteins that trigger transcript destabilization. For example, Vts1p, the S. cerevisiae member of the Smaug family of RNA binding proteins, is
Externí odkaz:
https://doaj.org/article/d7c3ffe5155142fd848d5f732e19c6e9
Autor:
Marja I. Roslund, Riikka Puhakka, Noora Nurminen, Sami Oikarinen, Nathan Siter, Mira Grönroos, Ondřej Cinek, Lenka Kramná, Ari Jumpponen, Olli H. Laitinen, Juho Rajaniemi, Heikki Hyöty, Aki Sinkkonen, Damiano Cerrone, Nan Hui, Iida Mäkelä, Anirudra Parajuli, Mika Saarenpää, Laura Soininen, Yan Sun, Heli K. Vari
Publikováno v:
Environment International, Vol 157, Iss , Pp 106811- (2021)
Background: In modern urban environments children have a high incidence of inflammatory disorders, including allergies, asthma, and type 1 diabetes. The underlying cause of these disorders, according to the biodiversity hypothesis, is an imbalance in
Externí odkaz:
https://doaj.org/article/7afe46d7bece4b6b8b96a3f9ecfc37c6
Autor:
Nan Hui, Anirudra Parajuli, Riikka Puhakka, Mira Grönroos, Marja I. Roslund, Heli K. Vari, Ville A.O. Selonen, Guoyang Yan, Nathan Siter, Noora Nurminen, Sami Oikarinen, Olli H. Laitinen, Juho Rajaniemi, Heikki Hyöty, Aki Sinkkonen
Publikováno v:
Environment International, Vol 132, Iss , Pp - (2019)
An agricultural environment and exposure to diverse environmental microbiota has been suggested to confer protection against immune-mediated disorders. As an agricultural environment may have a protective role, it is crucial to determine whether the
Externí odkaz:
https://doaj.org/article/6365181adf724582a52a5f5a4efcf476
Autor:
Nan Hui, Mira Grönroos, Marja I. Roslund, Anirudra Parajuli, Heli K. Vari, Laura Soininen, Olli H. Laitinen, Aki Sinkkonen, The ADELE Research Group
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Human activities typically lead to simplified urban diversity, which in turn reduces microbial exposure and increases the risk to urban dwellers from non-communicable diseases. To overcome this, we developed a microbial inoculant from forest and agri
Externí odkaz:
https://doaj.org/article/091d91df43564196b78c383a89802402
Autor:
Anirudra Parajuli, Mira Grönroos, Nathan Siter, Riikka Puhakka, Heli K. Vari, Marja I. Roslund, Ari Jumpponen, Noora Nurminen, Olli H. Laitinen, Heikki Hyöty, Juho Rajaniemi, Aki Sinkkonen
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Expanding urbanization is a major factor behind rapidly declining biodiversity. It has been proposed that in urbanized societies, the rarity of contact with diverse environmental microbiota negatively impacts immune function and ultimately increases
Externí odkaz:
https://doaj.org/article/9d2fcf5c94fb4b9fa15ae3661df31cdd
Autor:
Mira Grönroos, Anirudra Parajuli, Olli H. Laitinen, Marja I. Roslund, Heli K. Vari, Aki Sinkkonen, Riikka Puhakka, Heikki Hyöty
Publikováno v:
MicrobiologyOpen
Immune-mediated diseases have increased during the last decades in urban environments. The hygiene hypothesis suggests that increased hygiene level and reduced contacts with natural biodiversity are related to the increase in immune-mediated diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784b49dc25b7c5c44e4a5d09fe32d74c
http://hdl.handle.net/10138/238903
http://hdl.handle.net/10138/238903
Autor:
Heli K. Vari, Sami Oikarinen, Noora Nurminen, Jake Lin, Olli H. Laitinen, Hanna Viskari, Heikki Hyöty, Riikka Puhakka, Ondrej Cinek, Anirudra Parajuli, Aki Sinkkonen, Iiris Tyni, Lenka Kramna, Mira Grönroos, Marja I. Roslund
Publikováno v:
Future microbiology. 13
Aim: Current attempts to modulate the human microbiota and immune responses are based on probiotics or human-derived bacterial transplants. We investigated microbial modulation by soil and plant-based material. Materials & methods: We performed a pil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349511ca5384bfb96428672671e5e249
https://pubmed.ncbi.nlm.nih.gov/29771153
https://pubmed.ncbi.nlm.nih.gov/29771153
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e47121 (2012)
PLoS ONE, Vol 7, Iss 10, p e47121 (2012)
Sequence-specific RNA binding proteins can induce the degradation of mRNAs through their ability to recruit proteins that trigger transcript destabilization. For example, Vts1p, the S. cerevisiae member of the Smaug family of RNA binding proteins, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a384114c421d219bb247acf739a56566
https://pubmed.ncbi.nlm.nih.gov/23071728
https://pubmed.ncbi.nlm.nih.gov/23071728
Autor:
Heli K. Vari, Ramona L. Cooperstock, Craig A. Smibert, Hua Luo, Jennifer L. Semotok, Angelo Karaiskakis, Howard D. Lipshitz
SMAUG (SMG) is an RNA-binding protein that functions as a key component of a transcript degradation pathway that eliminates maternal mRNAs in the bulk cytoplasm of activated Drosophila melanogaster eggs. We previously showed that SMG destabilizes mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0df92c7d1aa877a5bae45e237c3e7ae
https://europepmc.org/articles/PMC2573300/
https://europepmc.org/articles/PMC2573300/
Autor:
Meryl R. Nelson, Heli K. Vari, Hua Luo, Craig A. Smibert, Henry M. Krause, Andrew J. Simmonds, Howard D. Lipshitz, Brian J. Cox
Publikováno v:
The Journal of biological chemistry. 282(47)
Modulating the efficiency of translation plays an important role in a wide variety of cellular processes and is often mediated by trans-acting factors that interact with cis-acting sequences within the mRNA. Here we show that a cis-acting element, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5609b68d03769d328ea53af96f868c
https://pubmed.ncbi.nlm.nih.gov/17890223
https://pubmed.ncbi.nlm.nih.gov/17890223