Remodeling of the brain angioarchitecture in experimental chronic neurodegeneration

Autor: Thomsen, Maj Schneider, Kostrikov, Serhii, Routhe, Lisa Greve, Johnsen, Kasper Bendix, Helgudóttir, Steinunn Sara, Gudbergsson, Johann Mar, Andresen, Thomas Lars, Moos, Torben

Publikováno v: In Neurobiology of Disease January 2025 204

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A novel strategy for delivering Niemann-Pick type C2 proteins across the blood-brain barrier using the brain endothelial-specific AAV-BR1 virus

Autor: Rasmussen, Charlotte Laurfelt Munch, Hede, Eva, Routhe, Lisa Juul, Körbelin, Jakob, Helgudottir, Steinunn Sara, Thomsen, Louiza Bohn, Schwaninger, Markus, Burkhart, Annette, Moos, Torben

Publikováno v: Rasmussen, C L M, Hede, E, Routhe, L J, Körbelin, J, Helgudottir, S S, Thomsen, L B, Schwaninger, M, Burkhart, A & Moos, T 2023, ' A novel strategy for delivering Niemann-Pick type C2 proteins across the blood-brain barrier using the brain endothelial-specific AAV-BR1 virus ', Journal of Neurochemistry, vol. 164, no. 1, pp. 6-28 . https://doi.org/10.1111/jnc.15621

Treating central nervous system (CNS) diseases is complicated by the incapability of numerous therapeutics to cross the blood–brain barrier (BBB), mainly composed of brain endothelial cells (BECs). Genetically modifying BECs into protein factories

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c174b638762f5934e1749e85a40b7ea9
https://vbn.aau.dk/da/publications/92d8a9c4-0a20-4ac1-b254-b2189e96e900

Expressional prerequisites for targeted drug delivery to the pathological brain

Autor: Helgudottir, Steinunn Sara

Publikováno v: Helgudottir, S S 2021, Expressional prerequisites for targeted drug delivery to the pathological brain . Aalborg Universitet. Det Sundhedsvidenskabelige Fakultet. Ph.D.-Serien, Aalborg Universitetsforlag . https://doi.org/10.54337/aau424058297

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2079ae3c185603d43a241ab826435c91
https://vbn.aau.dk/ws/files/424058297/PHD_SSH_E_pdf.pdf

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