Evidence for a two-metal-ion mechanism in the cytidyltransferase KdsB, an enzyme involved in lipopolysaccharide biosynthesis.

Autor: Helgo Schmidt, Jeroen R Mesters, Jing Wu, Ronald W Woodard, Rolf Hilgenfeld, Uwe Mamat

Publikováno v: PLoS ONE, Vol 6, Iss 8, p e23231 (2011)

Lipopolysaccharide (LPS) is located on the surface of Gram-negative bacteria and is responsible for maintaining outer membrane stability, which is a prerequisite for cell survival. Furthermore, it represents an important barrier against hostile envir

Externí odkaz: https://doaj.org/article/45058fedffa54cddafc403b8013a07f5

In vitro characterization of the full-length human dynein-1 cargo adaptor BicD2

Autor: Robert Fagiewicz, Corinne Crucifix, Torben Klos, Célia Deville, Bruno Kieffer, Yves Nominé, Johan Busselez, Paola Rossolillo, Helgo Schmidt

SUMMARYCargo adaptors are crucial in coupling motor proteins with their respective cargos and regulatory proteins. BicD2 is a prominent example within the cargo adaptor family. BicD2 is able to recruit the microtubule motor dynein to RNA, viral parti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e380a4b9be5bf7d92e4479a5c04f5773
https://doi.org/10.1101/2022.01.05.474964

Review: Structure and mechanism of the dynein motor ATPase

Autor: Helgo Schmidt, Andrew P. Carter

Publikováno v: Biopolymers

Dyneins are multiprotein complexes that move cargo along microtubules in the minus end direction. The largest individual component of the dynein complex is the heavy chain. Its C‐terminal 3500 amino‐acid residues form the motor domain, which hydr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8294c18c67a3b5deb4a0978b7babf2e1
https://doi.org/10.1002/bip.22856

Author response: The CryoEM structure of the Saccharomyces cerevisiae ribosome maturation factor Rea1

Autor: J. Busselez, P. Sosnowski, R. Fagiewicz, Gabor Papai, Andreas Boland, Helgo Schmidt, Linas Urnavicius

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4590c7eb6053f9dddaa42ac4fbca794a
https://doi.org/10.7554/elife.39163.045

List of Contributors

Autor: Adam W. Avery, Gordon K. Chan, Anudariya B. Dean, Paurav B. Desai, Ian R. Gibbons, Thomas S. Hays, Edward H. Hinchcliffe, Yuqing Hou, Emily L. Hunter, Juyeon Hwang, Takashi Ishikawa, Rupam Jha, Ritsu Kamiya, Stephanie A. Ketcham, K. Kevin Pfister, Stephen M. King, Cody W. Lewis, Min-Gang Li, Richard J. McKenney, David R. Mitchell, Amanda L. Neisch, Mary E. Porter, Winfield S. Sale, Trina A. Schroer, Chikako Shingyoji, Thomas Surrey, Noriko Ueki, Richard B. Vallee, Kevin T. Vaughan, Ken-ichi Wakabayashi, Bill Wickstead, Maureen Wirschell, George B. Witman, Xin Xiang, Toshiki Yagi, Lionel Berthoux, Andrew P. Carter, Amrita Dawn, David J. Doobin, Mike Fainzilber, Elizabeth M.C. Fisher, Ken’ya Furuta, Veikko F. Geyer, Steven P. Gross, William O. Hancock, Kent L. Hill, Erika L.F. Holzbaur, Jonathon Howard, Simon Imhof, Kazuo Inaba, Frank Jülicher, Tarun M. Kapoor, Sandip Koley, Christine M. Lightcap, Niki T. Loges, Miroslav P. Milev, Hannah M. Mitchison, Armen J. Moughamian, Andrew J. Mouland, Kazuhiro Oiwa, Heymut Omran, Stephen H. Pilder, Michael Price, Babu J.N. Reddy, Hitoshi Sakakibara, Pablo Sartori, Helgo Schmidt, Miriam Schmidts, Amanda E. Siglin, Joseph H. Sisson, Jonathan B. Steinman, George T. Shubeita, Marco Terenzio, John B. Vincent, John C. Williams, Fan Yang, Xaojian Yao, Ahmet Yildiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a4fc3e596df0e76a7b86db619d9e001
https://doi.org/10.1016/b978-0-12-809471-6.01002-0