Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Helgi Kuzmychova"'
Autor:
Emma Martell, Helgi Kuzmychova, Harshal Senthil, Esha Kaul, Chirayu R. Chokshi, Chitra Venugopal, Christopher M. Anderson, Sheila K. Singh, Tanveer Sharif
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Despite tremendous research efforts, successful targeting of aberrant tumor metabolism in clinical practice has remained elusive. Tumor heterogeneity and plasticity may play a role in the clinical failure of metabolism-targeting intervention
Externí odkaz:
https://doaj.org/article/6a8d4e7ad8b24e438bb93abf59e42c2c
Autor:
Emma Martell, Helgi Kuzmychova, Esha Kaul, Harshal Senthil, Subir Roy Chowdhury, Ludivine Coudière Morrison, Agnes Fresnoza, Jamie Zagozewski, Chitra Venugopal, Chris M. Anderson, Sheila K. Singh, Versha Banerji, Tamra E. Werbowetski-Ogilvie, Tanveer Sharif
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-26 (2023)
Abstract Group 3 medulloblastoma (G3 MB) carries the worst prognosis of all MB subgroups. MYC oncoprotein is elevated in G3 MB tumors; however, the mechanisms that support MYC abundance remain unclear. Using metabolic and mechanistic profiling, we pi
Externí odkaz:
https://doaj.org/article/5c5a7943a1a04bfc88a6392559029355