Zobrazeno 1 - 10
of 682
pro vyhledávání: '"Helgi B. Schiöth"'
Long-term changes in adiposity markers during and after antidepressant therapy in a community cohort
Autor:
Jessica Mwinyi, Marie-Pierre F. Strippoli, Sofia H. Kanders, Helgi B. Schiöth, Chin B. Eap, Aurélie M. Lasserre, Pedro Marques-Vidal, Caroline L. Vandeleur, Martin Preisig
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Research on antidepressant-related weight changes over more than 12 months is scarce and adjustment for the effects of depressive episodes has rarely been applied. Accordingly, our aim was to assess the associations of the use of any antidep
Externí odkaz:
https://doaj.org/article/b1116ce266d74025abebd9e39f5aba3e
Autor:
Salahuddin Mohammad, Mélissa Gentreau, Manon Dubol, Gull Rukh, Jessica Mwinyi, Helgi B. Schiöth
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Previous research on autism spectrum disorders (ASD) have showed important volumetric alterations in the cerebellum and brainstem. Most of these studies are however limited to case-control studies with small clinical samples and including ma
Externí odkaz:
https://doaj.org/article/2a62513784754a00909ba7e176f81443
Autor:
Eugenia D. Namiot, Diana Smirnovová, Aleksandr V. Sokolov, Vladimir N. Chubarev, Vadim V. Tarasov, Helgi B. Schiöth
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Major depressive disorder (MDD), commonly known as depression, affects over 300 million people worldwide as of 2018 and presents a wide range of clinical symptoms. The international clinical trials registry platform (ICTRP) introduced by WHO
Externí odkaz:
https://doaj.org/article/b8df8f8d7cd54867b9542d7c81a07943
Autor:
Aleksandr V. Sokolov, Helgi B. Schiöth
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The causes of depression are complex, and the current diagnosis methods rely solely on psychiatric evaluations with no incorporation of laboratory biomarkers in clinical practices. We investigated the stability of blood DNA methylation depre
Externí odkaz:
https://doaj.org/article/a61203813d6c480fb611ce26ed8a9a6c
Autor:
Andrey D. Bondarev, Jörgen Jonsson, Vladimir N. Chubarev, Vadim V. Tarasov, Francisco Alejandro Lagunas-Rangel, Helgi B. Schiöth
Publikováno v:
Pharmacological Research, Vol 209, Iss , Pp 107431- (2024)
The nucleic acid topoisomerases (TOP) are an evolutionary conserved mechanism to solve topological problems within DNA and RNA that have been historically well-established as a chemotherapeutic target. During investigation of trends within clinical t
Externí odkaz:
https://doaj.org/article/378ffe8ffaa24923896eb52a6efbdfc2
Autor:
Shanshan Xiao, Håkan Fischer, Natalie C. Ebner, Gull Rukh, Junhua Dang, Lars Westberg, Helgi B. Schiöth
Publikováno v:
Comprehensive Psychoneuroendocrinology, Vol 20, Iss , Pp 100255- (2024)
Genetic variations in single nucleotide polymorphisms (SNPs) within oxytocin pathway genes have been linked to social behavior and neurodevelopmental conditions. However, the neurobiological mechanisms underlying these associations remain elusive. In
Externí odkaz:
https://doaj.org/article/11c54eae0ab343a7970242d380202653
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Subjective well-being (SWB) is associated with social support in cross-sectional studies. However, it remains unclear whether and how social support predicts SWB longitudinally, especially during the COVID-19 contingency. Methods
Externí odkaz:
https://doaj.org/article/1278481ae3684a87bac14f68043d6ebc
Autor:
Na Zhao, Xiaoyu Zhang, Xilong Wang, Zhipu Liu, Guixi Zheng, Xin Zhang, Helgi B. Schiöth, Chengxi Sun, Hongxing Wang, Yi Zhang
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
Liver metabolites are involved in the progression of rheumatoid arthritis (RA), indicating a connection between the liver and joints. However, the impact and mechanism of Hepatitis B virus (HBV), a hepatotropic virus, on RA are still unclear. We inve
Externí odkaz:
https://doaj.org/article/3399f117658941a9a0f3fa9b0920bc18
Autor:
Trishna A. Desai, Åsa K. Hedman, Marios Dimitriou, Mine Koprulu, Sandy Figiel, Wencheng Yin, Mattias Johansson, Eleanor L. Watts, Joshua R. Atkins, Aleksandr V. Sokolov, Helgi B. Schiöth, Marc J. Gunter, Konstantinos K. Tsilidis, Richard M. Martin, Maik Pietzner, Claudia Langenberg, Ian G. Mills, Alastair D. Lamb, Anders Mälarstig, Tim J. Key, Ruth C. Travis, Karl Smith-Byrne
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105168- (2024)
Summary: Background: Understanding the role of circulating proteins in prostate cancer risk can reveal key biological pathways and identify novel targets for cancer prevention. Methods: We investigated the association of 2002 genetically predicted ci
Externí odkaz:
https://doaj.org/article/1ace1755f8ce4d638c80b4c3f3d25968
Autor:
Mohamed H. Al-Sabri, Nourhane Ammar, Stanislava Korzh, Ahmed M. Alsehli, Kimia Hosseini, Robert Fredriksson, Jessica Mwinyi, Michael J. Williams, Hadi Boukhatmi, Helgi B. Schiöth
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Previously, we showed that fluvastatin treatment induces myofibrillar damage and mitochondrial phenotypes in the skeletal muscles of Drosophila. However, the sequential occurrence of mitochondrial phenotypes and myofibril damage remains elus
Externí odkaz:
https://doaj.org/article/f778552c72294911b629376c6860df04