Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Helge Roider"'
Autor:
Helge Roider, Sami Ventelä, Arndt Schmitz, Oliver von Ahsen, Elke Schmid, Bastian Gebhart, Johannes Routila, Sami Sebastian Khaznadar, Martin Khan, Eva T Becker, Merja Perala, Thomas Krahn
Publikováno v:
Head & Neck. 42:625-635
Background MET has emerged as target in head and neck squamous cell carcinoma (HNSCC). However, clinical data on MET inhibition in HNSCC are limited. Methods HNSCC biopsies and cell lines were tested for MET activity. The response of cell lines to BA
Autor:
Helge Roider, Su-Yi Tseng, Sabine Hoff, Sandra Berndt, Katharina Filarski, Uwe Gritzan, Beatrix Stelte-Ludwig, Wiebke M. Nadler, Joanna Grudzinska-Goebel, Philipp Ellinger, Mark Trautwein, Matyas Gorjanacz
Publikováno v:
Cancer Research. 82:2866-2866
Regulatory T cells (Tregs) play an indispensable role in mediating peripheral tolerance to self-antigens. They can also promote tumor growth by suppressing the function of effector CD8+ and CD4+ T cells in the tumor microenvironment (TME). Furthermor
Autor:
Leena Halim, Antonella Adami, Balázs Győrffy, Lynsey M. Whilding, Benjamin Draper, Ana C. Parente-Pereira, Domenico Cozzetto, Chung-Yang Ricardo Joseph, Helge Roider, Chelsea A. Taylor, Jana Obajdin, Holger Hess-Stumpp, Jinger Xie, Ayesha Iqbal, Richard Beatson, Tomasz Zabinski, Fred Aswad, John Maher, Tom Hardiman, Jelmar Quist, Anette Sommer, Caroline M. Hull, Andrew Tutt, Daniela Achkova, Kim Ngan Luu Hoang, David M. Davies, Rafael Torres Martin de Rosales, Anita Grigoriadis, Francis Man
Publikováno v:
SSRN Electronic Journal.
Despite their role in cancer surveillance, adoptive immunotherapy using γδ T-cells has achieved limited efficacy. To enhance trafficking to bone marrow, circulating γδ T-cells were expanded in serum-free medium containing TGF-β1 and IL-2 (γδ[T
Autor:
Minghui Dong, Xueda Hu, Rui Xing, Lei Zhang, Helge Roider, Boxi Kang, Jintao Song, Qiming Zhang, Zhouzerui Liu, Guo Xinyi, Tiansheng Yan, Dennis Kirchhoff, Zemin Zhang, Chunhong Zheng, Xianwen Ren, Ranran Gao, Liangtao Zheng, Yuanyuan Zhang, Liang Jin
Publikováno v:
Nature Medicine. 24:978-985
Cancer immunotherapies have shown sustained clinical responses in treating non-small-cell lung cancer1–3, but efficacy varies and depends in part on the amount and properties of tumor infiltrating lymphocytes4–6. To depict the baseline landscape
Autor:
Ranran Gao, Tiansheng Yan, Zemin Zhang, Lei Zhang, Liang Jin, Liangtao Zheng, Yuanyuan Zhang, Jintao Song, Guo Xinyi, Qiming Zhang, Helge Roider, Boxi Kang, Minghui Dong, Zhouzerui Liu, Chunhong Zheng, Xianwen Ren, Xueda Hu, Rui Xing, Dennis Kirchhoff
Publikováno v:
Nature Medicine. 24:1628-1628
In the version of this article originally published, the P statistic described in Fig. 3d was incorrect. It was described as "P < 22 × 10-16". It should have been "P < 2.2 × 10-16". Also, the "CD8+ Treg" label in Fig. 4f was incorrect. It should ha
Autor:
Andrew Pow, Spencer Liang, Wolf-Dietrich Doecke, Helge Roider, Ofer Levy, Julia Huetter, John J. Hunter, Sven Golfier, Lars Roese, Zurit Levine, Uwe Gritzan, Ilona Gutcher, Ilan Vaaknin, Merlin Verena Luetke-Eversloh, Bertolt Kreft
Publikováno v:
Cancer Research. 78:2778-2778
ILDR2 is a type I transmembrane protein belonging to the B7 family of immunomodulatory receptors with 98 % sequence identity between the extracellular domains of human and murine orthologues. The exact physiological role of ILDR2 is still unclear, bu