Zobrazeno 1 - 10 of 156 pro vyhledávání: '"Helge Refsum"'
1
Age Impacts Olanzapine Exposure Differently During Use of Oral Versus Long-Acting Injectable Formulations
Autor: Christoph U. Correll, Marit Tveito, Gudrun Høiseth, Espen Molden, Cecilie B. Hartberg, Robert Løvsletten Smith, Tore Haslemo, Helge Refsum
Publikováno v: Journal of Clinical Psychopharmacology. 38:570-576
PURPOSE Olanzapine is a commonly prescribed antipsychotic available as oral and long-acting injectable (LAI) formulations. Data are lacking on the use and safety of olanzapine-LAI in older patients. The aim of this study was to investigate the effect
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db8a9b997e175bf0ff1745d69dfd4da
https://doi.org/10.1097/jcp.0000000000000961
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2
A five-year follow-up study of antioxidants, oxidative stress and polyunsaturated fatty acids in schizophrenia
Autor: Ole A. Andreassen, Håvard Bentsen, Helge Refsum, Dag Kristen Solberg
Publikováno v: Acta neuropsychiatrica. 31(4)
Objective:Oxidative stress and dysregulated antioxidant defence may be involved in the pathophysiology of schizophrenia. In the present study, we investigated changes in antioxidants and oxidative stress from an acute to a later stable phase. We hypo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3455c58c671be070991d41d6019f329f
https://pubmed.ncbi.nlm.nih.gov/31178002
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5
Impact of age, gender and CYP2C9/2C19 genotypes on dose-adjusted steady-state serum concentrations of valproic acid—a large-scale study based on naturalistic therapeutic drug monitoring data
Autor: Tore Haslemo, Robert Løvsletten Smith, Helge Refsum, Espen Molden
Publikováno v: European Journal of Clinical Pharmacology. 72:1099-1104
Valproic acid (VPA) has an extensive interindividual pharmacokinetic variability. Published data regarding the impact of gender, age, and CYP2C9/2C19 genetics on VPA variability are conflicting, and the purpose of present study is to clarify the effe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3c45ff2ac169a5fed83432c51b8399
https://doi.org/10.1007/s00228-016-2087-0
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6
Clinically Relevant Effect of UGT1A4*3 on Lamotrigine Serum Concentration Is Restricted to Postmenopausal Women-A Study Matching Therapeutic Drug Monitoring and Genotype Data From 534 Patients
Autor: Tore Haslemo, Espen Molden, Helge Refsum, Robert Løvsletten Smith, Hilde F. Chan
Publikováno v: Therapeutic drug monitoring. 40(5)
Previous studies have reported inconsistent findings regarding the impact of the UGT1A4*3 variant allele on lamotrigine (LTG) exposure. As no studies have controlled for nongenetic factors, the aim of this study was to compare serum concentrations of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a6051b108071ce837490ec92688124
https://pubmed.ncbi.nlm.nih.gov/30086088
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7
Correlates of major medication side effects interfering with daily performance: results from a cross-sectional cohort study of older psychiatric patients
Autor: Bernhard Lorentzen, Marit Tveito, Helge Refsum, Gudrun Høiseth, Christoph U. Correll, Knut Engedal, Jørgen G. Bramness
Publikováno v: International Psychogeriatrics. 28:331-340
Background:Polypharmacy is common among older persons who are also vulnerable to side effects. We aimed to characterize patients who on admission to a geriatric psychiatric hospital had major medication side effects interfering with daily performance
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca94ae81782ba44695516075bb1c73f
https://doi.org/10.1017/s1041610215001544
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9
Psychotropic medication in geriatric psychiatric patients: use and unreported use in relation to serum concentrations
Autor: Marit Tveito, Gudrun Høiseth, Jørgen G. Bramness, Knut Engedal, Bernhard Lorentzen, Helge Refsum
Publikováno v: European Journal of Clinical Pharmacology. 70:1139-1145
The aim of this observational study was to describe the type, number, and serum concentration levels of psychotropic drugs in elderly patients, on admission to a geriatric psychiatric inpatient unit. We further wanted to investigate the use and unrep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd6a4a1e23c01a698780a576f59a3cf
https://doi.org/10.1007/s00228-014-1720-z
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10
A Clinical Study of the Cognitive Effects of Benzodiazepines in Psychogeriatric Patients
Autor: Marit Tveito, Lars Tanum, Kari Midtbø Kristiansen, Jørgen G. Bramness, K Kvande, Gudrun Høiseth, Helge Refsum, Bernhard Lorentzen
Publikováno v: Pharmacopsychiatry. 46:209-213
Previous studies have shown cognitive impairment in long-term benzodiazepine users compared to non-users. However, little is known about such effects in a population of geriatric psychiatry patients. The aim of this study was to identify differences
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44685cae6a85c6416bc3d0c454363f6a
https://doi.org/10.1055/s-0033-1349131
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