Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Helge Rask-Andersen"'
Autor:
Wei Liu, Hao Li, Charlotta Kämpfe Nordström, Niklas Danckwardt-Lillieström, Sumit Agrawal, Hanif M. Ladak, Helge Rask-Andersen
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundDespite its location near infection-prone areas, the human inner ear demonstrates remarkable resilience. This suggests that there are inherent instruments deterring the invasion and spread of pathogens into the inner ear. Here, we combined
Externí odkaz:
https://doaj.org/article/b52cb74e416f4b5dbeb788142e5830f2
Autor:
Karin Hallin, Helge Rask-Andersen
Publikováno v:
Acta Oto-Laryngologica Case Reports, Vol 7, Iss 1, Pp 39-43 (2022)
We present a pitch discrimination test performed by five experienced adult auditory brainstem implant (ABI) users with neurofibromatosis type 2 (NF2). The ability to discriminate frequency/pitch from different channels on the implant may be an import
Externí odkaz:
https://doaj.org/article/b8d3888c43b2416c8b717de72a328a96
Autor:
Hao Li, Sumit Agrawal, Seyed Alireza Rohani, Ning Zhu, Daniela I. Cacciabue, Marcelo N. Rivolta, Douglas E. H. Hartley, Dan Jiang, Hanif M. Ladak, Gerard M. O’Donoghue, Helge Rask-Andersen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract The human inner ear contains minute three-dimensional neurosensory structures that are deeply embedded within the skull base, rendering them relatively inaccessible to regenerative therapies for hearing loss. Here we provide a detailed chara
Externí odkaz:
https://doaj.org/article/310d5f761a524f2aba9f4b36e30d57cb
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: An endocochlear potential (EP) exists in the mammalian cochlea generated by the stria vascularis and an associated fibrocyte network. It plays an essential role for sensory cell function and hearing sensitivity. In non-mammalian ectotherm
Externí odkaz:
https://doaj.org/article/6e25061521b74ad48384cb9c23ac29d5
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-23 (2021)
Abstract Background Sensorineural hearing loss is one of the most common sensory deficiencies. However, the molecular contribution to age-related hearing loss is not fully elucidated. Methods We performed genome-wide association studies (GWAS) for he
Externí odkaz:
https://doaj.org/article/524d03e479484351bc94aec5a516b972
Autor:
Wei Liu, Helge Rask-Andersen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
BackgroundGap junction (GJ) proteins, connexin26 and 30, are highly prevalent in the human cochlea (HC), where they are involved in transcellular signaling, metabolic supply, and fluid homeostasis. Their genes, GJB2 and GJB6, are both located at the
Externí odkaz:
https://doaj.org/article/329c23a2b64040d7aa8bd80b9abf6fca
Autor:
Claudia Steinacher, Lejo Johnson Chacko, Wei Liu, Helge Rask-Andersen, Werner Bader, Jozsef Dudas, Consolato M. Sergi, Tamilvendhan Dhanaseelan, Nadjeda Moreno, Rudolf Glueckert, Romed Hoermann, Anneliese Schrott-Fischer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundHuman inner ear contains macrophages whose functional role in early development is yet unclear. Recent studies describe inner ear macrophages act as effector cells of the innate immune system and are often activated following acoustic traum
Externí odkaz:
https://doaj.org/article/cc09affbb34c4a018b6d447b3052b1c3
Autor:
Christine Ölander, Jesper Edvardsson Rasmussen, Per Olof Eriksson, Göran Laurell, Helge Rask-Andersen, Jonas Bergquist
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The endolymphatic sac (ES) is the third part of the inner ear, along with the cochlea and vestibular apparatus. A refined sampling technique was developed to analyse the proteomics of ES endolymph. With a tailored solid phase micro-extractio
Externí odkaz:
https://doaj.org/article/6571bad6f4f64b12a083a15bfd7b8998
Autor:
Hao Li, Karin Staxäng, Monika Hodik, Karl-Gunnar Melkersson, Mathias Rask-Andersen, Helge Rask-Andersen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: In several non-mammalian species, auditory receptors undergo cell renewal after damage. This has raised hope of finding new options to treat human sensorineural deafness. Uncertainty remains as to the triggering mechanisms and whether hai
Externí odkaz:
https://doaj.org/article/9cdfb5e9558c4a2e921c0ef3884fc16c
Autor:
Hao Li, Luke Helpard, Jonas Ekeroot, Seyed Alireza Rohani, Ning Zhu, Helge Rask-Andersen, Hanif M. Ladak, Sumit Agrawal
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract The human cochlea transforms sound waves into electrical signals in the acoustic nerve fibers with high acuity. This transformation occurs via vibrating anisotropic membranes (basilar and tectorial membranes) and frequency-specific hair cell
Externí odkaz:
https://doaj.org/article/db803eafe12944599f1cbd5b4e42650e