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pro vyhledávání: '"Helge Nickel"'
Autor:
Kim Ohl, Helge Nickel, Halima Moncrieffe, Patricia Klemm, Anja Scheufen, Dirk Föll, Viktor Wixler, Angela Schippers, Norbert Wagner, Lucy R. Wedderburn, Klaus Tenbrock
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 16, Iss 1, Pp 1-9 (2018)
Abstract Background Inflammatory effector T cells trigger inflammation despite increased numbers of Treg cells in the synovial joint of patients suffering from juvenile idiopathic arthritis (JIA). The cAMP response element (CREM)α is known to play a
Externí odkaz:
https://doaj.org/article/5e072fbd3fc54050b8bb98a7a51a0503
Autor:
Patricia Klemm, Dirk Föll, Anja Scheufen, Viktor Wixler, Lucy R. Wedderburn, Halima Moncrieffe, Klaus Tenbrock, Angela Schippers, Norbert Wagner, Helge Nickel, Kim Ohl
Publikováno v:
Pediatric Rheumatology Online Journal
Pediatric Rheumatology Online Journal, Vol 16, Iss 1, Pp 1-9 (2018)
Pediatric rheumatology 16(1), 39 (2018). doi:10.1186/s12969-018-0253-x
Pediatric Rheumatology Online Journal, Vol 16, Iss 1, Pp 1-9 (2018)
Pediatric rheumatology 16(1), 39 (2018). doi:10.1186/s12969-018-0253-x
Background Inflammatory effector T cells trigger inflammation despite increased numbers of Treg cells in the synovial joint of patients suffering from juvenile idiopathic arthritis (JIA). The cAMP response element (CREM)α is known to play a major ro
Publikováno v:
The Journal of Immunology. 192:177.1-177.1
The cAMP response element (CRE) modulator (CREM)α binds to genes promoters with CREs and regulates transcription via a chromatin-dependent mechanism. CREMα is important for the T cell pathophysiology of SLE suppressing IL-2 and CD3ζ transcription,
Publikováno v:
Pediatric Rheumatology Online Journal
The cAMP response element (CRE) modulator (CREM)α binds to promoters of genes with CREs and regulates transcription via a chromatin-dependent mechanism. CREMα is important for the T cell pathophysiology of SLE by suppression of IL-2 and CD3ζ but e