Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Helge Grunwald"'
Autor:
Dominique Klauer, Goetz Schlotterbeck, Mathias Wind, Arnaud Serafyn, Helge Grunwald, Michael Schleimer, Patrick Hargreaves, Klaus Gebhardt, Anne Schmitt-Hoffmann
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 85:138-144
A systematic comparison between two labeling approaches for the investigation of the in vitro metabolic pattern of pharmaceutical drugs was performed by examining the use of (i) radiolabeled drugs analyzed with LC-MS-offline radiodetection and (ii) s
Autor:
Anne Schmitt-Hoffmann, Dominique Klauer, Mathias Wind, Patrick Roussel, Helge Grunwald, Michael Schleimer, Pascal Fullhardt, Jochen Spickermann, Klaus Illig, Claude Nuoffer, Klaus Gebhardt
Publikováno v:
Journal of Chromatography A. 1216:3946-3953
The in vitro metabolic profile of BAL30630, an antifungal piperazine propanol derivative, which inhibits the 1,3-beta- d -glucansynthase, was investigated by incubation with microsomes of several species and with rat hepatocytes. For the spotting of
Autor:
Laurenz Kellenberger, Marc Muller, Massimiliano Donzelli, Jochen Spickermann, Anne Schmitt-Hoffmann, Pascal Fullhardt, Klaus Gebhardt, Michael Schleimer, Mathias Wind, Helge Grunwald
Publikováno v:
Rapid communications in mass spectrometry : RCM. 21(7)
The in vitro metabolic pattern of BAL19403, a novel macrolide antibiotic, was investigated by capillary liquid chromatography/quadrupole time-of-flight mass spectrometry (LC/QTOF-MS) in incubations with human microsomes. For the elucidation of the me