In-depth cell-free DNA sequencing reveals genomic landscape of Hodgkin's lymphoma and facilitates ultrasensitive residual disease detection

Autor: Peter Borchmann, Stefanie Kreissl, Esther E.E. Drees, Roland T. Ullrich, Sarah Reinke, Elena Gerhard-Hartmann, Anton Hagenbeek, Sophia Sobesky, Josée M. Zijlstra, Andreas Rosenwald, Bastian von Tresckow, Wolfram Klapper, D.M. Pegtel, Melita Cirillo, Jonathan Weiss, Janine Altmüller, Paul J Bröckelmann, Margaretha G.M. Roemer, Laman Mammadova, Stephanie Sasse, Helge Dörr, Julia Mattlener, Andreas Engert, Sven Borchmann, Zhiyuan Shi, Peter Nürnberg

Publikováno v: Sobesky, S, Mammadova, L, Cirillo, M, Drees, E E E, Mattlener, J, Dörr, H, Altmüller, J, Shi, Z, Bröckelmann, P J, Weiss, J, Kreissl, S, Sasse, S, Ullrich, R T, Reinke, S, Klapper, W, Gerhard-Hartmann, E, Rosenwald, A, Roemer, M G M, Nürnberg, P, Hagenbeek, A, Zijlstra, J M, Pegtel, D M, Engert, A, Borchmann, P, von Tresckow, B & Borchmann, S 2021, ' In-depth cell-free DNA sequencing reveals genomic landscape of Hodgkin's lymphoma and facilitates ultrasensitive residual disease detection ', Med, vol. 2, no. 10, pp. 1171-1193.e11 . https://doi.org/10.1016/j.medj.2021.09.002
Med (New York, N.Y.), 2(10), 1171-1193.e11. Cell Press
Med, 2(10), 1171-1193.e11. Cell Press

Summary Background Individualization of treatment in Hodgkin’s lymphoma is necessary to improve cure rates and reduce treatment side effects. Currently, it is hindered by a lack of genomic characterization and sensitive molecular response assessmen

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https://research.vumc.nl/en/publications/8da398e7-192c-412f-b985-e71916868ffd